Protein Alignment CG34393 and ralgds

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_005167239.1
• Gene: ralgds / 799483
• ZFINID: ZDB-GENE-081105-110
• Length: 837
• Species: Danio rerio
• Alignment Length: 886
• Identity: 158/886 - (17%)
• Similarity: 283/886 - (31%)
• Gaps: 346/886 - (39%)

  Fly    54 ISSNSSSTDSESADECGLELGESGA-------DSREAGAGGGAGLQVAQGGIFSLDPGHLTAETA 111
            |.|::......|.|    ||.||..       |..:.....|.|..|.......|||.....|::
Zfish     7 IQSDALGVKPTSLD----ELFESSTWRIKNIWDGVKLEIAAGDGCPVVLNSFTHLDPDLPMLESS 67

  Fly   112 L--LGGNIRYRRRHSAEQLSAYDLEMGFQQLELGTTISVGPK------NEDLVQYDVPKNPHKRS 168
            :  :|..:        |..:.|.:.:  ::::|..|.|.|.:      :..|..|:..|
Zfish    68 VQEIGEEV--------EDGAIYTITL--RKVQLHQTASKGQRWLGVETDSALSLYETCK------ 116

  Fly   169 QCDINFESSVLGSGGIMYINGR-IVSGPLDSLIETLLP----KDVVDLDKEFVFSFLLSCRLFLR 228
                                || |.:|.|:.|:|.::.    ||..     :|..||.:.|.|..
Zfish   117 --------------------GRTIKAGTLEKLVEYMVSAFKGKDYT-----YVTIFLCTYRAFAT 156

  Fly   229 PHELLGRLLD---SVPES-----------ECLESLVSLLAEWTMKFPYDY----RDERMMSHVKH 275
            ..::|..||:   .:|.|           |...::.|:|..|..::..|:    ..|.:.|.:.:
Zfish   157 TKQVLDLLLNRYAKLPASGKTKVSAEDHTELKNTVSSILGAWLDQYSEDFWSPPDHECLQSLISY 221

  Fly   276 IVARCSNSHLEAAVSQTLSALLKRLTDLERHEADLRACQTNDKSGPETPLNCPTATQYAQIVCRV 340
            :....|.|.||           :|..:|..|....:.|:...:.   ...:||.||.       .
Zfish   222 LQLNFSGSDLE-----------RRALNLLEHFQHRQQCEVEIEG---DLCSCPFATP-------E 265

  Fly   341 EKKLAKHIGGEEFLQCSSMILLDKQ--------KK----------WDQPSTSGAPPGAQDPKKT- 386
            |..|........|:..|..|:.::.        |:          |.|....|....|...:.|
Zfish   266 ESSLEDEFSPSHFMSFSPSIVAEQLTVMDAELFKRVVPYHCLGGIWSQRDKKGKEHLAPTIRATV 330

  Fly   387 --------CNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAIL 443
                    |.:.|.|| :..||.|            .|::.:|.|..||:.|.::.:::|..|||
Zfish   331 SQFNSVTNCVIATCLD-NRSLRPF------------QRAKRIEHWIEVARKCRILKSFSSLKAIL 382

  Fly   444 ESLESPAIARLKITWSKLQ----VTCQQLD---------------------------------CM 471
            .:|:|.||.||:..|..:.    .|.|:|.                                 ..
Zfish   383 SALQSNAIHRLRRAWDDVSRESYRTFQELSEIFSDDNNYSLSRELLIKEGTSKSAIVEINHKGAQ 447

  Fly   472 QRHAEGH---------------------------GHL---------------------------- 481
            :||.:..                           .||
Zfish   448 RRHQQQRDMGVVQGTIPYLGTFLTDLVMLDTAMKDHLEVGLINFEKRRKEFEVIAQIKLLQLTCN 512

  Fly   482 ------------WQKQAISLNEQQE-GLKTDKQAPKEPAAQ----------------GAAP---- 513
                        |.|:...|.|.:. .:..|.:.|.|...:                .||.
Zfish   513 YYNFSRNQRFIDWFKRVEKLTETESYSMSCDIEPPSESLCKKNGGIMKRMSEESGYSSAASHSKS 577

  Fly   514 -------------TQGAVAIAITTS----SDSDE--------------------KPSTSGRVAGI 541
                         ..||.::::|::    ||:||                    |.|::.....:
Zfish   578 FEQPRLSQFKDCFKDGADSLSLTSAGSSGSDADESLSLLNSPESGSQRTSTPTVKHSSTSETGEL 642

  Fly   542 AGISAATMESAPVP---VASGSN--VDAATAAAARTSTTAATTPLASSGKPNDWVVIPV--FADI 599
            ...|:..:..:|.|   .||||.  :::..:::..:|::::::..|.:|:..::....|  .:|.
Zfish   643 PSDSSTKLWESPTPSSLEASGSGLCLESGCSSSTSSSSSSSSSVSAFTGRTFNFHKRSVSGISDY 707

  Fly   600 VKLAL---GEREN--CLQRLA----NGH----INMAAFDRMAAIV-GAFTKHMQAMKAAQAPSSG 650
            ..|:|   .::.|  |:.|::    ||:    |.:.:.|:...:: .|..||     ......|.
Zfish   708 SSLSLPLYNQQANDCCIIRVSLDSENGNMYKSILVTSQDKTPGVIRKAMAKH-----NLDNDKSE 767

  Fly   651 EYEHFCRHMQQTTKLGEAELMMASFDCEEPNNAEKLMYDLN 691
            :||    .:|:.:|..|..:         |:|. .:.|.:|
Zfish   768 DYE----LLQRVSKHKELRI---------PDNG-NVFYAMN 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	26/125 (21%)
		RasGEF	334..>473	CDD:279011	38/202 (19%)
ralgds	XP_005167239.1	RasGEFN	116..240	CDD:214571	33/165 (20%)
		RasGEF	278..543	CDD:238087	44/277 (16%)
		RalGDS_RA	721..806	CDD:176351	19/93 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910