Protein Alignment CG34393 and Sos

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: NP_476597.2
• Gene: Sos / 34790
• FlyBaseID: FBgn0001965
• Length: 1596
• Species: Drosophila melanogaster
• Alignment Length: 622
• Identity: 111/622 - (17%)
• Similarity: 213/622 - (34%)
• Gaps: 204/622 - (32%)

  Fly   145 TISVGPKNEDLVQYDVP-KNPHKRSQCDINFESSVLGSGGIMYINGR-------IVSGPLDSLIE 201
            |.|:..::.|.:..|:. |:|.:....:| ::.:|..||..:.:..|       |....|..|||
  Fly   588 TKSMLDRHLDSILQDIERKHPLRMPSPEI-YKFAVPDSGDNIVLEERESAGVPMIKGATLCKLIE 651

  Fly   202 TLLPKDVVDLDKEFVFSFLLSCRLFLRPHELLGRLLD--SVPESECLES---------------- 248
            .|...  :..|..||.:||.:.|.|..|.:||..|::  ::|:...:..
  Fly   652 RLTYH--IYADPTFVRTFLTTYRYFCSPQQLLQLLVERFNIPDPSLVYQDTGTAGAGGMGGVGGD 714

  Fly   249 -------------------------LVSLLAEWTMKFPYDYRD-----ERMMSHVKHIVARCSNS 283
                                     ::::|..|.....||:..     |::::.::|:..:....
  Fly   715 KEHKNSHREDWKRYRKEYVQPVQFRVLNVLRHWVDHHFYDFEKDPMLLEKLLNFLEHVNGKSMRK 779

  Fly   284 HLEAAVSQTLSALLKRLTDLERHEADLRACQTNDKSGPETPLNCPT---------ATQYAQIVCR 339
            .:::.:.     :::|..:.|:....:.....:|....|..|:.|.         ..:.|:.:..
  Fly   780 WVDSVLK-----IVQRKNEQEKSNKKIVYAYGHDPPPIEHHLSVPNDEITLLTLHPLELARQLTL 839

  Fly   340 VEKKLAKHIGGEEFLQCSSMILLDKQKKWDQPSTSGAPPGAQDPK-KTCNLETYLDWSARLRLFV 403
            :|.::.|::...|.:                    |:|...:|.: |:.||...:..:..:..::
  Fly   840 LEFEMYKNVKPSELV--------------------GSPWTKKDKEVKSPNLLKIMKHTTNVTRWI 884

  Fly   404 CNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSATAILESLESPAIARLKIT-------WSKL 461
            ...|.::...|.|...::....|....|.:.|:|...:|:.::.:.::.||:.|       :.|.
  Fly   885 EKSITEAENYEERLAIMQRAIEVMMVMLELNNFNGILSIVAAMGTASVYRLRWTFQGLPERYRKF 949

  Fly   462 QVTCQQL--DCMQRHAE------------------------------------------------ 476
            ...|::|  |.::::.|
  Fly   950 LEECRELSDDHLKKYQERLRSINPPCVPFFGRYLTNILHLEEGNPDLLANTELINFSKRRKVAEI 1014

  Fly   477 -GHGHLWQKQAISLNEQQ------------EGLKTDKQ-------------------APKEP--- 506
             |....:|.|...|||:.            .|| :|||                   .||.|
  Fly  1015 IGEIQQYQNQPYCLNEESTIRQFFEQLDPFNGL-SDKQMSDYLYNESLRIEPRGCKTVPKFPRKW 1078

  Fly   507 -----AAQGAAPTQGAVAIAITTSSDSDEKPSTSGRVAGIAGISAAT-MESAPVPVASGSNV-DA 564
                 .:.|..|.:     ...|:|.|....|||...|..|..|.|| :.:|..|....|:: ||
  Fly  1079 PHIPLKSPGIKPRR-----QNQTNSSSKLSNSTSSVAAAAAASSTATSIATASAPSLHASSIMDA 1138

  Fly   565 ATAAAARTSTTAATTPLASSGKP-NDWVVIPVFADIV 600
            .|||||    .|.:..||....| ::.....|||.::
  Fly  1139 PTAAAA----NAGSGTLAGEQSPQHNPHAFSVFAPVI 1171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	23/151 (15%)
		RasGEF	334..>473	CDD:279011	25/148 (17%)
Sos	NP_476597.2	Histone	90..216	CDD:278551
		H2A	155..>196	CDD:305064
		RhoGEF	249..432	CDD:238091
		PH_SOS	476..586	CDD:269963
		PH	482..587	CDD:278594
		RasGEFN	637..791	CDD:214571	24/160 (15%)
		RasGEF	825..1062	CDD:238087	37/257 (14%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010