Protein Alignment CG34393 and rapgef6

DIOPT Version :9

• Sequence 1: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_017208494.2
• Gene: rapgef6 / 335032
• ZFINID: ZDB-GENE-030131-6972
• Length: 1546
• Species: Danio rerio
• Alignment Length: 548
• Identity: 121/548 - (22%)
• Similarity: 196/548 - (35%)
• Gaps: 159/548 - (29%)

  Fly     7 ASKISA------IACG--TRCKQTVLQKSRGQRDRDKCHHGHHQHHRRHHRRRCRISSNSSSTDS 63
            |||:..      |||.  .:|:|..||||                        ||.|....:...
Zfish   517 ASKMKGHLRLLNIACAAKAKCRQVTLQKS------------------------CRESPLMFNLQG 557

  Fly    64 ESADECGLELGESGADSREAGAGGGAGLQVAQ--GGIF-------SLD----PGH--LTAETAL- 112
            .|....|:.:.....:||.|.||...|.||.:  |..|       ::|    ..|  ||.:|.:
Zfish   558 GSERGFGIFIESVEPNSRAAEAGLKRGDQVLEINGQNFENISYTKAMDILKNNTHLSLTVKTNIF 622

  Fly   113 ----LGGNIRYRRRH-----------SAEQLSAYDL--EMGF------QQLELGTTISVGPKNE- 153
                |...:|:.:::           .:.:.|..||  :|.|      .:.....|:| |.:|:
Zfish   623 VFKELQSRMRHEKKNGGPHIPKIQERKSNRFSIPDLPGDMEFPTDSKSHKKMKANTVS-GGRNKI 686

  Fly   154 ----DLVQYDV-PKNPHKRSQCDINFESSVLG------SGGIMYINGRIVSGPLDSLIETLLPKD 207
                :..::.: |..|...|....:.:.|::|      |..||.|.|.:.|...|     ||...
Zfish   687 RKMLEKTRFSILPPKPFSDSGVCQSQDDSIVGTKQCRHSVAIMPIPGSLSSSSPD-----LLQPA 746

  Fly   208 VVDLDKEFVFSFLLSCRLFLRPHELLGRLLDSVPESECLESLVSLLAEWTMKFPYDYRDERMMSH 272
            ...||             |..|.::..::: .|.:::...:.:.:..:.|.|        .::||
Zfish   747 ATVLD-------------FSNPSDIPDQVI-RVFKADQQSAYIIISKDTTAK--------DVVSH 789

  Fly   273 VKH----IVARCSNSHLEAAVSQTLSALLKRLTDLERHEADLRACQTND----KSGPETPLNC-- 327
            |..    |.|..:.|..|.:||.......:||.|.....||  ..|.|.    |:..||...|
Zfish   790 VVSEFGLIAAAETYSLCEVSVSPEGVIKQRRLPDQLSKLAD--RIQLNGRYYLKNNMETETLCSD 852

  Fly   328 -----------------PTATQYAQIVCRVEKKLAKHIGGEEFLQCSSMILLDKQKKWDQPSTSG 375
                             .|....||:..| :..|.::|...|::  ..:..||       |...|
Zfish   853 EDAQDLLRESQISLLQLSTVEVAAQLSMR-DFSLFRNIESTEYV--DDLFKLD-------PGGGG 907

  Fly   376 APPGAQDPKKTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSGVAQYCLLVGNYNSAT 440
            .....:..::..|.||:  |       |..|||:......|.:|::.:..:|.:|....|:||..
Zfish   908 GAGHLKQFEEIINQETF--W-------VSTEILREPNAIKRMKTIKHFIKIALHCRECKNFNSMF 963

  Fly   441 AILESLESPAIARLKITWSKLQVTCQQL 468
            ||:..|....:|||:.||.||....::|
Zfish   964 AIISGLNLAPVARLRSTWEKLPSKYEKL 991

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34393	NP_001285578.1	REM	196..300	CDD:100121	19/107 (18%)
		RasGEF	334..>473	CDD:279011	36/135 (27%)
rapgef6	XP_017208494.2	CAP_ED	49..154	CDD:320730
		cNMP	290..405	CDD:197516
		RasGEFN	421..534	CDD:214571	6/16 (38%)
		PDZ_signaling	538..618	CDD:238492	24/103 (23%)
		UBQ	759..843	CDD:320785	20/94 (21%)
		RasGEF	866..1102	CDD:214539	37/145 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910