Protein Alignment gkt and tdp1

DIOPT Version :9

• Sequence 1: NP_523465.2
• Gene: gkt / 33530
• FlyBaseID: FBgn0260817
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: NP_001039242.1
• Gene: tdp1 / 734106
• XenbaseID: XB-GENE-950568
• Length: 597
• Species: Xenopus tropicalis
• Alignment Length: 600
• Identity: 206/600 - (34%)
• Similarity: 293/600 - (48%)
• Gaps: 98/600 - (16%)

  Fly     4 CPYGEKCYRK---NPIHFGEFSHAHLDAIYAKGNESGDYEIPANYSSEMIHTQLKLL-------- 57
            |....|...|   ||:.|.|.|...|              |||    :.|.|:.::.
 Frog    48 CSDARKASHKRKANPVKFKEMSKKEL--------------IPA----KKIKTETEVSGWCLSSSD 94

  Fly    58 EKLFPKQATNKEQEAHSSSSKPAVTAPVASGSSSSGSLDTN--PSGSSASGPAASQDTSNLAKKQ 120
            |:..|.|.   ||:.:..:.|..|..       .|..:..|  ........|:.||||.:|
 Frog    95 EESKPTQV---EQKGNIKADKIEVLV-------QSKKIQENIEVKQKKCKTPSDSQDTWDL---- 145

  Fly   121 KLNAKNIRDYIPVVIEKGGMAKKLERAAPYNMFLTAITDSKPTHSEPLSITLQEILDESLGEIES 185
                                   |:...|:..:||.:...||.::.. ::.:::||....|.:.|
 Frog   146 -----------------------LQAGEPFRFYLTKVMGIKPKYNSG-ALHIKDILSPLFGTLVS 186

  Fly   186 TVQINFMVDIGWLLGHYYFAGILDKPLLLLYGDESPELLSIGKFKQQVTAIRV---KMPTPFATS 247
            :.|.|:..||.||:..|. ....|||||:::|::......:.:.......||:   |:...|.|.
 Frog   187 SAQFNYCFDIKWLVKQYP-EEFRDKPLLIVHGEKRESKAKLHEDAHPYEHIRLCQAKLDIAFGTH 250

  Fly   248 HTKMMFLGYSDGSMRVVISTANLYEDDWHNRTQGLWISPKLPALPVDADTGAGESLTGFKQDLML 312
            |||||.|.|::| :||||.|:||..:||:.:|||:|:||..|.||..|...||||.|.|:.||:.
 Frog   251 HTKMMLLLYTEG-LRVVIHTSNLIHEDWYQKTQGIWLSPLYPRLPEGASVSAGESSTNFRSDLVA 314

  Fly   313 YLVEYKISQLQPWIARIRNSDFSAINVFFLGSVPGGHREGSVRGHPWGHARLASLLAKH--AAPI 375
            ||..|....|:.|:..|:..|.|...|:.:||.| |..:|:.: ..|||.||..||.::  |||.
 Frog   315 YLASYNSPSLREWMDIIKQHDLSETRVYLIGSTP-GRFQGNDK-DKWGHFRLRKLLRENTSAAPG 377

  Fly   376 DDRIPVVCQSSSIGSLGANVQAWIQQDFVNSLKKDSTPVGK-LRQMP----PFKMIYPSYGNVAG 435
            .:..||:.|.|||||:|.:...|:..:|..||    |.:|| ::.:.    |..:||||..||..
 Frog   378 QETWPVIGQFSSIGSMGVDKTKWLCSEFTESL----TTLGKSIKSLQKTEIPLHLIYPSVDNVRT 438

  Fly   436 SHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSDRFRSRAMPHIKSYTRFNLEDQSVYWFVLTS 500
            |.:|...||.|||...|..|||||..|..:||:....||:||||||:|.|.:.:.|.:.||::||
 Frog   439 SLEGYPAGGSLPYSIQTAQKQPWLHSYFHKWKAETSRRSQAMPHIKTYMRLSPDSQHLAWFLVTS 503

  Fly   501 ANLSKAAWGCFNKNSNIQPCLRIANYEAGVLFLP-RFVTGEDTFPL-----GNNRDGVPAFPLPY 559
            |||||||||...||.   ..|.|.:||.|||||| .|.|  :||.:     .:|.....|||:||
 Frog   504 ANLSKAAWGSLEKNG---AQLFIRSYELGVLFLPSAFET--NTFNVKLNIYASNEPSSNAFPVPY 563

  Fly   560 DVPLTPYAPDDKPFL 574
            |:|...|...|:|::
 Frog   564 DLPPEHYGAKDRPWV 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gkt	NP_523465.2	zf-CCHH	2..23	CDD:287283	7/21 (33%)
		PLDc_mTdp1_1	149..317	CDD:197289	64/170 (38%)
		Tyr-DNA_phospho	153..567	CDD:283694	172/429 (40%)
		PLDc_mTdp1_2	339..534	CDD:197291	89/201 (44%)
tdp1	NP_001039242.1	PLDc_mTdp1_1	150..319	CDD:197289	64/171 (37%)
		Tyr-DNA_phospho	153..571	CDD:283694	172/431 (40%)
		PLDc_mTdp1_2	341..534	CDD:197291	89/201 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	287	1.000	Domainoid score	I1565
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5424
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58389
OrthoDB	1	1.010	-	-		D1295967at2759
OrthoFinder	1	1.000	-	-		FOG0003245
OrthoInspector	1	1.000	-	-		otm49295
Panther	1	1.100	-	-	LDO	PTHR12415
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3767
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.030