Protein Alignment gkt and gkt

DIOPT Version :10

• Sequence 1: NP_523465.2
• Gene: gkt / 33530
• FlyBaseID: FBgn0260817
• Length: 580
• Species: Drosophila melanogaster
• Sequence 2: XP_061515583.1
• Gene: gkt / 1275307
• VectorBaseID: AGAMI1_013383
• Length: 635
• Species: Anopheles gambiae
• Alignment Length: 625
• Identity: 326/625 - (52%)
• Similarity: 415/625 - (66%)
• Gaps: 56/625 - (8%)

  Fly     2 KECPYGEKCYRKNPIHFGEFSHAHLDAIYAKGNESGDYEIP--ANYSSEMIHTQLKLLEKLFPK- 63
            |||.||..|||.||:||.|::|.|::.:..|.......|||  ...:..:...|||::..|||.
Mosquito    15 KECQYGGDCYRVNPVHFREYAHPHIEKLLVKAASLSMVEIPDDVKVNKSVFTEQLKIVSSLFPHL 79

  Fly    64 --QATNKE----QEAHSSSSKPAVTAPVASGSSSSGSL-DTNPSGSSA----------------- 104
              .:||.|    ||..:|...|.|   .::|:..|||: ..||..|||
Mosquito    80 SCDSTNPEKKPKQEPTTSKPPPVV---ASAGAVPSGSVPKANPKPSSADNKNSIEALFAERRAKM 141

  Fly   105 -----SGPA------ASQD--------TSNLA--KKQKLNAKNIRDYIPVVIEKGGMAKKLERAA 148
                 |.||      |.|:        |||..  ..||...::|..|.|||..:|.||:||..||
Mosquito   142 QATQQSKPAPESVVPAKQETYTPNRPTTSNNTGISLQKALPRDINSYFPVVAPRGQMAQKLAAAA 206

  Fly   149 PYNMFLTAITDSKPTHSEPLSITLQEILDESLGEIESTVQINFMVDIGWLLGHYYFAGILDKPLL 213
            |||.|||.||.|||||:||||:|.||:||.||||:|.:||:||||||||||.||:|||..:.|||
Mosquito   207 PYNFFLTTITASKPTHAEPLSVTFQELLDSSLGELECSVQMNFMVDIGWLLAHYFFAGYENVPLL 271

  Fly   214 LLYGDESPELLSIGKFKQQVTAIRVKMPTPFATSHTKMMFLGYSDGSMRVVISTANLYEDDWHNR 278
            :|||||:|||..:.:.|..|||::|::.|||...||||...||.|||:|||:|||||||||||||
Mosquito   272 ILYGDETPELRMVSQKKPNVTAVKVEIKTPFGVHHTKMGLYGYRDGSIRVVVSTANLYEDDWHNR 336

  Fly   279 TQGLWISPKLPALPVDADTGAGESLTGFKQDLMLYLVEYKISQLQPWIARIRNSDFSAINVFFLG 343
            ||||||||:|||:|..:||..|||.:.|:..|:.||..||:.|||||:||||.:|||.:.||.:.
Mosquito   337 TQGLWISPRLPAVPEGSDTTYGESRSDFRSSLLTYLDAYKLPQLQPWMARIRKTDFSDVKVFLVA 401

  Fly   344 SVPGGHREGSVRGHPWGHARLASLLAKHAAPIDDRIPVVCQSSSIGSLGANVQAWIQQDFVNSLK 408
            |||||| ..:.:|..|||.||..||::|||||||..|:|.|||||||||.:.::|:..:.:.|.:
Mosquito   402 SVPGGH-TNTAKGPLWGHPRLGYLLSQHAAPIDDSCPLVAQSSSIGSLGPSPESWVLGEIMASFR 465

  Fly   409 KDSTPVGKLRQMPPFKMIYPSYGNVAGSHDGMLGGGCLPYGKNTNDKQPWLKDYLQQWKSSDRFR 473
            |||.||| :|::|.|:|||||:.||..|||||:|||||||.::|:.||.|||||||||.|..|.|
Mosquito   466 KDSAPVG-IRRLPGFRMIYPSFSNVRQSHDGMMGGGCLPYVRSTHVKQEWLKDYLQQWCSRARHR 529

  Fly   474 SRAMPHIKSYTRFNLEDQSVYWFVLTSANLSKAAWGCFNKNSNIQPCLRIANYEAGVLFLPRFVT 538
            ::||||||:|.|::  .:.:|||:||||||||||||.:||....:..|||.:|||||||||:.:.
Mosquito   530 NKAMPHIKTYCRWS--HRGLYWFLLTSANLSKAAWGVYNKTGRFEKPLRINSYEAGVLFLPKLLL 592

  Fly   539 GEDTFPLGNNRDGVPAFPLPYDVPLTPYAPDDKPFLMDYL 578
            .|:.||:..|:.. |.||:|||||..||||:|.||.||||
Mosquito   593 DENFFPMEANKKH-PQFPMPYDVPTIPYAPEDTPFFMDYL 631

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gkt	NP_523465.2	zf-CCHH	3..25	CDD:463043	13/21 (62%)
		Tyr-DNA_phospho	152..567	CDD:461824	249/414 (60%)
gkt	XP_061515583.1	None