Protein Alignment Mad and gb:cr929477

DIOPT Version :9

• Sequence 1: NP_001259992.1
• Gene: Mad / 33529
• FlyBaseID: FBgn0011648
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_009299441.1
• Gene: gb:cr929477 / 794669
• ZFINID: ZDB-GENE-141211-39
• Length: 505
• Species: Danio rerio
• Alignment Length: 495
• Identity: 192/495 - (38%)
• Similarity: 258/495 - (52%)
• Gaps: 93/495 - (18%)

  Fly    98 VKKLLGWKQGDEEEKWAEKAVDSLVKKLKKRKGAIEELERALSCPG-QPSKCVTIPRSLDGRLQV 161
            |..|:..:||.|.|.::::|::|||||||::|..::.|..|::..| .|||||||.|:|||||||
Zfish    17 VHSLMCHRQGGESESFSKRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQV 81

  Fly   162 SHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRVESPVLP-PVLV- 224
            :.|||.|||||.|:||||||.. :|||.::.||:.|..|...||:|||||:||.||.:. .||.
Zfish    82 AGRKGFPHVIYARLWRWPDLHK-NELKHVKYCQFAFDLKCDNVCVNPYHYERVVSPSIDLSVLTL 145

  Fly   225 ------------------PRHSEFAPGHSMLQFNHVAEPSMPHNVSYSNSGFNSHSL-----STS 266
                              ..||....|||:....|.|.||.|.:.      |||..|     .||
Zfish   146 GGPGPSGELMVKEEFEGQSSHSAADGGHSIQTIQHTATPSAPPDT------FNSPVLLPPADHTS 204

  Fly   267 NTSVGSPSSVNSNP-NSPYDSLAGTPPPAYSPSEDGNSNN----PNDGGQLLDAQMGDVAQ---- 322
            :||..:.|::.:.| |:|.....|:..|...|.::|:..:    |:.|      |...|..
Zfish   205 STSTSAFSAMAAGPNNAPSSWPRGSSFPPSIPHQNGHLQHHPPLPHTG------QYWSVHNELAF 263

  Fly   323 ----VSYSEPAFWASIAYYELNCRVGEVFHCNNNS--VIVDGFTNPSNNSDRCCLGQLSNVNRNS 381
                .::..|.:|.||||:|::.:|||.|...:|.  |.|||:.:|| ..||.||||||||:|..
Zfish   264 QPPISTHPAPDYWCSIAYFEMDIQVGETFKVPSNCPVVTVDGYVDPS-GGDRFCLGQLSNVHRTE 327

  Fly   382 TIENTRRHIGKGVHLYYV-TGEVYAECLSDSAIFVQSRNCNYHHGFHP-STVCKIPPGCSLKIFN 444
            .||..|.||||||.|... .|:|:..||||.|:||||...:...|..| ..|.||.|...:|:|:
Zfish   328 AIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 392

  Fly   445 NQE-----------------------------------FAQLLSQSVNNGFEAVYELTKMCTIRM 474
            .::                                   .|..:|.|...|. .|.:|.::|.:||
Zfish   393 LRQCHRQMQQQAATAQAAAAAQADAVAGNIPGPGSVGGIAPAISLSAAAGI-GVDDLRRLCILRM 456

  Fly   475 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 514
            |||||||.:|.||.:..||||||||||..||.||:||..|
Zfish   457 SFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLHTM 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mad	NP_001259992.1	MH1_SMAD_1_5_9	93..216	CDD:199814	64/118 (54%)
		MH2_SMAD_1_5_9	325..525	CDD:199822	94/229 (41%)
gb:cr929477	XP_009299441.1	MH1_SMAD_4	11..135	CDD:199816	64/118 (54%)
		MH2_SMAD_4	273..494	CDD:199823	92/222 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910