DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment Mad and tmem54

DIOPT Version :10

Sequence 1:	NP_001259992.1	Gene:	Mad / 33529	FlyBaseID:	FBgn0011648	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_002940070.3	Gene:	tmem54 / 100485545	XenbaseID:	XB-GENE-490434	Length:	221	Species:	Xenopus tropicalis

Alignment Length:	25	Identity:	11/25 - (44%)
Similarity:	14/25 - (56%)	Gaps:	4/25 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   501 HGPLQWLDKVLTQMGSPHNAISSVS 525
            |.||:|...||..:    |||.||:
Frog    86 HVPLRWTVLVLGII----NAILSVA 106

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mad	NP_001259992.1	MH1_SMAD_1_5_9	93..216	CDD:199814
Mad	NP_001259992.1	MH2_SMAD_1_5_9	325..525	CDD:199822	10/23 (43%)
tmem54	XP_002940070.3	BCLP	17..192	CDD:463527	11/25 (44%)
Blue background indicates that the domain is not in the aligned region.

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