DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment FASN1 and AT4G21580

DIOPT Version :9

Sequence 1:	NP_001137778.2	Gene:	FASN1 / 33524	FlyBaseID:	FBgn0283427	Length:	2540	Species:	Drosophila melanogaster
Sequence 2:	NP_193889.1	Gene:	AT4G21580 / 828243	AraportID:	AT4G21580	Length:	325	Species:	Arabidopsis thaliana

Alignment Length:	339	Identity:	91/339 - (26%)
Similarity:	139/339 - (41%)	Gaps:	58/339 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly  1565 VKGDLASLKWIEAA--QADTAATVDKNLETCTVYYAPINFRDVMLTSGKLAADALPGDLAEQDCV 1627
            ||.|...::.:..|  :|||       |:...:|..|                  ||    ....
plant    25 VKDDEVLIRVLATALNRADT-------LQRLGLYNPP------------------PG----SSPY 60

  Fly  1628 LGLEFAG----------RDTQGRRVMAMVPAKSLATTCVASKRMMWQIPEKWTMEEASTVPCVYS 1682
            ||||.:|          |...|.:|.|::.....|.........::.||...::::|:..|.|..
plant    61 LGLECSGTIESVGKGVSRWKVGDQVCALLSGGGYAEKVSVPAGQIFPIPAGISLKDAAAFPEVAC 125

  Fly  1683 TVYYALVVRGQMKKGEKILIHAGSGGVGQAAISVALAHGLTVFTTVGSKEKREFLLKRFPKLQER 1747
            ||:..:.:.|::..||..|||.||.|:|..||.:|...|:.||.|.||.||    |....:|...
plant   126 TVWSTVFMMGRLSVGESFLIHGGSSGIGTFAIQIAKHLGVRVFVTAGSDEK----LAACKELGAD 186

  Fly  1748 NIGNSRDTSFEQLVLRETKGRGVDLVLNSLSEEKLQASIRCLGLNGRFLEIGKFDLSNNSPLGMS 1812
            ...|.:...|...|..||.|:|||::|:.:....||.::..|..:||...||... ..|:.:.:|
plant   187 VCINYKTEDFVAKVKAETDGKGVDVILDCIGAPYLQKNLDSLNFDGRLCIIGLMG-GANAEIKLS 250

  Fly  1813 VFL--KNTSFHGILLDSVMEGEEEMQNQVVSLVAEGIKTGAVVP-----LPTSVFNDQQVEQAFR 1870
            ..|  :.|.....|.....|.:..:..:|...|...|:.|.|.|     ||.|     |..:...
plant   251 SLLPKRLTVLGAALRPRSPENKAVVVREVEKNVWPAIEAGKVKPVIYKYLPLS-----QAAEGHS 310

  Fly  1871 FMASGKHIGKVVIK 1884
            .|.|..||||::::
plant   311 LMESSNHIGKILLE 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
FASN1	NP_001137778.2	PksD	137..1142	CDD:225858
		PKS	140..544	CDD:238429
		KAsynt_C_assoc	502..612	CDD:292814
		Acyl_transf_1	633..950	CDD:298668
		hot_dog	990..1234	CDD:294345
		NADB_Rossmann	1358..>1550	CDD:304358
		PKS_ER	1593..1883	CDD:214840	83/306 (27%)
		enoyl_red	1595..1883	CDD:176179	83/304 (27%)
		KR_1_FAS_SDR_x	<1901..2141	CDD:187657
		PKS_PP	2154..>2206	CDD:214834
		Abhydrolase	2286..2535	CDD:304388
AT4G21580	NP_193889.1	p53_inducible_oxidoreductase	1..323	CDD:176180	91/336 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	47	1.000	Domainoid score	I4520
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1090
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910