DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17221 and YIM1

DIOPT Version :9

Sequence 1:	NP_001259984.1	Gene:	CG17221 / 33521	FlyBaseID:	FBgn0031500	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_013872.1	Gene:	YIM1 / 855183	SGDID:	S000004760	Length:	365	Species:	Saccharomyces cerevisiae

Alignment Length:	378	Identity:	85/378 - (22%)
Similarity:	145/378 - (38%)	Gaps:	98/378 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 NECLVRIRATAVNPIDLAMLRGYGATVLNKMRCQPGDGIEFPLILGREFCGELVQTGMGVS--LP 143
            :|.::.:.|.|:||||....:...:.:..|          :|....|::.|.:::.|..|.  ..
Yeast    36 DEVVIEVHAAALNPIDFITHQLCNSYIFGK----------YPKTYSRDYSGVIIKAGKDVDNRWK 90

  Fly   144 LGSRVWGVVP-LQATIGSHAEYVA------VPSYCLAPAPKELDD------YEAASVLYAGLTAW 195
            :|.:|.|:.. :....|:...|:.      ||...:...||:.:|      |.||..|..| ||:
Yeast    91 VGDKVNGMYSHIYGERGTLTHYLILNPAKDVPITHMVEVPKDENDPYDDFVYAAAWPLTFG-TAF 154

  Fly   196 SGLYITGGLGGPCGATTASGGGAHKRVLVLGGSGGVGTLAIQILKS--QKVQVLATCSENAIEMV 258
            |.||           .......:..:|||:|.|..|....:.|.|:  ....|:..||:|:||..
Yeast   155 STLY-----------DFKKDWTSDSKVLVIGASTSVSYAFVHIAKNYFNIGTVVGICSKNSIERN 208

  Fly   259 RNLGADLVVDYNNPQAMEELCKYA-------PYDIVLDCAGQ----------------------- 293
            :.||.|.:|.|:....:|.:.|..       .:|::.|..|.
Yeast   209 KKLGYDYLVPYDEGSIVENVKKLKQSVLENDKFDMIFDSVGNHDFFPVIDQFLKPKAKNSFYVTI 273

  Fly   294 -GGQKAAESKYDFRQYITFSSPLLANIDKQGLGVGALKNVFDLFQTNVRSVTQRGGLVKWGFFSP 357
             |..||......:|.:::.||.|.|            .|.|..:              .|.|..|
Yeast   274 AGNNKADYKNISWRDFVSLSSILKA------------INPFKKY--------------NWRFGHP 312

  Fly   358 APQG--IQFLQKLVEQRKLMPLIDSSYGFSELPKAFEKMKSGHLRGKIVVKLR 408
            .|..  |:...:::::....|.|||.|.|.:..:|.:::.|...:||:|||::
Yeast   313 YPPNNFIEVGNEMIKKGTYKPPIDSVYEFDQYKEAIDRLMSNRAKGKVVVKMK 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17221	NP_001259984.1	RTN4I1	52..406	CDD:176210	83/374 (22%)
CG17221	NP_001259984.1	Qor	52..406	CDD:223677	83/374 (22%)
YIM1	NP_013872.1	AST1_like	8..364	CDD:176209	84/375 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345874
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0604
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I1716
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001925
OrthoInspector	1	1.000	-	-		oto100181
orthoMCL	1	0.900	-	-		OOG6_100491
Panther	1	1.100	-	-	LDO	PTHR11695
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3553
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780