Protein Alignment CG17221 and RTN4IP1

DIOPT Version :9

• Sequence 1: NP_001259984.1
• Gene: CG17221 / 33521
• FlyBaseID: FBgn0031500
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_116119.2
• Gene: RTN4IP1 / 84816
• HGNCID: 18647
• Length: 396
• Species: Homo sapiens
• Alignment Length: 379
• Identity: 138/379 - (36%)
• Similarity: 206/379 - (54%)
• Gaps: 35/379 - (9%)

  Fly    45 TSKSADKMRGWQLHNYGDIDELQLSEMLKIPQIRCSNECLVRIRATAVNPIDLAMLRGYGATVLN 109
            ||..:..|..|.:..||..:.|:.::.:.:|.|...||.:|::.|.:|||||:.|..|||||.||
Human    36 TSPRSTVMPAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSGYGATALN 100

  Fly   110 KMRCQP----GDGIEFPLILGREFCGELVQTGMGVS-LPLGSRVWGVVP--LQATIGSHAEYVAV 167
             |:..|    ..|.||||.|||:..|.:::.|:.|. ...|..||..||  .|.|:   :|:|.|
Human   101 -MKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPWKQGTL---SEFVVV 161

  Fly   168 PSYCLAPAPKELDDYEAASVLYAGLTAWSGLYITGGLGGPCGATTASGGGAHKRVLVLGGSGGVG 232
            ....::..||.|...:|||:.|..|||||.:...|||..    ...:|    ||||:||.|||||
Human   162 SGNEVSHKPKSLTHTQAASLPYVALTAWSAINKVGGLND----KNCTG----KRVLILGASGGVG 218

  Fly   233 TLAIQILKSQKVQVLATCSENAIEMVRNLGADLVVDYNNPQAMEELCKYAPYDIVLDCAGQGGQK 297
            |.|||::|:....|.|.||::|.|:||.||||.|:||.:....|:|....|:|.:||..|...:.
Human   219 TFAIQVMKAWDAHVTAVCSQDASELVRKLGADDVIDYKSGSVEEQLKSLKPFDFILDNVGGSTET 283

  Fly   298 AAE---SKYDFRQYITFSSPLLANIDKQGLGVGALKNVFDLFQTNVRSVTQ------RGGLVKWG 353
            .|.   .|:....|:|..:|.|.|:|:.|:..|.|       ||.|...::      :|...:|.
Human   284 WAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGML-------QTGVTVGSKALKHFWKGVHYRWA 341

  Fly   354 FFSPAPQGIQFLQKLVEQRKLMPLIDSSYGFSELPKAFEKMKSGHLRGKIVVKL 407
            ||..:...:..:.:||:..|:.|:|:.::.||::|:||.|::.||.|||.|:.:
Human   342 FFMASGPCLDDIAELVDAGKIRPVIEQTFPFSKVPEAFLKVERGHARGKTVINV 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17221	NP_001259984.1	RTN4I1	52..406	CDD:176210	136/369 (37%)
		Qor	52..406	CDD:223677	136/369 (37%)
RTN4IP1	NP_116119.2	RTN4I1	43..394	CDD:176210	136/369 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158308
Domainoid	1	1.000	82	1.000	Domainoid score	I8470
eggNOG	1	0.900	-	-		E1_COG0604
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13105
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3609
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53549
OrthoDB	1	1.010	-	-		D558414at33208
OrthoFinder	1	1.000	-	-		FOG0001925
OrthoInspector	1	1.000	-	-		oto91323
orthoMCL	1	0.900	-	-		OOG6_100491
Panther	1	1.100	-	-	LDO	PTHR11695
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3553
SonicParanoid	1	1.000	-	-		X3759
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800