Protein Alignment SerRS and SARS2

DIOPT Version :9

• Sequence 1: NP_001259982.1
• Gene: SerRS / 33518
• FlyBaseID: FBgn0031497
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_001139373.1
• Gene: SARS2 / 54938
• HGNCID: 17697
• Length: 520
• Species: Homo sapiens
• Alignment Length: 478
• Identity: 132/478 - (27%)
• Similarity: 219/478 - (45%)
• Gaps: 98/478 - (20%)

  Fly    78 SEDLPADVT--KDLTEI-------------VAETLQPLTVNQ----IKQLRV------------- 110
            |.||||.::  ::|.::             |.|.::.|..||    ::|:|:
Human    83 SADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQVRLDPGAGSIFGPTFL 147

  Fly   111 -------LIDDAMTENQ---KSLELAEQTRNTSLREVGNHLHESVPVSNDEDENRVERTFGD--- 162
                   |:.:|..|.|   ::|:|..||            |..||| .||.:.||....||
Human   148 PFPGQLSLLVEAQLEEQFYLQALKLPNQT------------HPDVPV-GDESQARVLHMVGDKPV 199

  Fly   163 --CEKRGKYSHVDLIVMIDGMNAEKGAVVSGGRGYFLTGAAVFLEQALIQHALHLLYARDYVPLY 225
              .:.||   |:::...:|.:..::.:.|||.|.|:|.||...|:..|:....:.|..|.:.|:.
Human   200 FSFQPRG---HLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMT 261

  Fly   226 TPFFMRKEVMQ--------EVAQLSQFDEELYKVVGKGSEKAEEVGIDEKYLIATSEQPIAAYHR 282
            .|..:|..|.:        ..:|:...|...:|               :..|..|:|..:|.|..
Human   262 VPDLLRGAVFEGCGMTPNANPSQIYNIDPARFK---------------DLNLAGTAEVGLAGYFM 311

  Fly   283 DEWLPESSLPIKYAGLSTCFRQEVGSHGRDTRGIFRVHQFEKVEQFVLTSPHDNKSWEMMDEMIG 347
            |..:....||::....|||:|.|..: |::.||::|||.|.|||.|.:|.|...:|.::::|.:.
Human   312 DHTVAFRDLPVRMVCSSTCYRAETNT-GQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLS 375

  Fly   348 NAEQFCQSLGIPYRVVNIVSGALNHAASKKLDLEAWFGGSGAYRELVSCSNCLDYQARRLLVRFG 412
            ...:....||:.:||:::.:..|...|.:|.|:|||..|.|.:.|:.|.|||.|:|:|||.:.|
Human   376 LQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMF- 439

  Fly   413 QTKKMNAAVDYVHMLNATMCAATRVICAILETHQTETG-IKVPEPLKKYMPAKFQDEIPFVKPAP 476
            ||:.  ..:.:.|.:|||.||..|::.|:||::|.:.| :.||..|:.|:..   |.|    .||
Human   440 QTEA--GELQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPALQSYLGT---DRI----TAP 495

  Fly   477 IDLELAAAEKQKGKKEKTKKDPA 499
            ..:.|......:.:|......||
Human   496 THVPLQYIGPNQPRKPGLPGQPA 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerRS	NP_001259982.1	PLN02678	3..476	CDD:215364	126/453 (28%)
		Seryl_tRNA_N	3..111	CDD:280549	13/71 (18%)
		SerRS_core	153..461	CDD:238393	96/321 (30%)
SARS2	NP_001139373.1	PRK05431	58..495	CDD:235461	126/453 (28%)
		SerRS_core	187..487	CDD:238393	96/321 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0172
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S479
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D495094at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100275
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.670