Protein Alignment SerRS and sars-2

DIOPT Version :10

• Sequence 1: NP_608743.2
• Gene: SerRS / 33518
• FlyBaseID: FBgn0031497
• Length: 501
• Species: Drosophila melanogaster
• Sequence 2: NP_500549.1
• Gene: sars-2 / 177200
• WormBaseID: WBGene00005662
• Length: 441
• Species: Caenorhabditis elegans
• Alignment Length: 485
• Identity: 133/485 - (27%)
• Similarity: 211/485 - (43%)
• Gaps: 115/485 - (23%)

  Fly     3 LDLDLFRSDKGGNPDLVRENQKKRFKDVALVETVIAKDTEWRQCRHRADNLNKVKNVCSKVIGEK 67
            |:.:....:|  |.:.:|||...| |.|..::.|..|   |                  .||.:.
 Worm    45 LNFEFLLDEK--NLEAIRENILNR-KGVGDIDKVHKK---W------------------AVIQKM 85

  Fly    68 MK--KKEPVGAMSEDLPADVTKDLTEIVAETLQPLTVNQIKQL-RVLIDDAMTENQKSLELAEQT 129
            ||  :|:..||:||                       .:.||| ..|.|:|:.
 Worm    86 MKSGEKQTNGAVSE-----------------------QKYKQLWDELYDEAIL------------ 115

  Fly   130 RNTSLREVGNHLHESVPVSNDEDENRVERTFGDCEKRGKYSHVDLIVMIDGMNAEK--------- 185
                   :.|...:.|| ...||:.::...:|  |||..          :.:.|||
 Worm   116 -------IPNMTQDGVP-RGSEDQAKIVAEWG--EKRED----------ECLTAEKLVQTWRSLL 160

  Fly   186 -GAVVSGGRGYFLTGAAVFLEQALIQHALHLLYARDYVPLYTPFFMRKEVMQEVAQLSQFDEEL- 248
             ....||.|.|...||...||:||:.:|...:.|..:.|:..|..:..||.|....:.:.|..:
 Worm   161 HPTDASGQRSYVFLGALASLEKALLDYAHERVCALGFRPITVPDIVSGEVTQACGVMQRSDHPIQ 225

  Fly   249 YKVVGKGSEKAEEVGIDEKYLIATSEQPIAAYHRDEWLPESSLPIKYAGLSTCFRQEVGSHGRDT 313
            |.:.|:.|...         |..|:|..|||:.|.....:..|||:...||.|||.|:.....:.
 Worm   226 YTLAGEESHTK---------LSGTAEMGIAAFLRGRTFNQDQLPIRLVSLSRCFRTEISKSASEA 281

  Fly   314 RGIFRVHQFEKVEQFVLTSPHDNKSWEMMDEMIGNAEQFCQSLGIPYRVVNIVSGALNHAASKKL 378
            : ::|||:|.|||.||:::|  .:|...:|.::...:...|:||:..|.:.:.|..|..:|::|.
 Worm   282 K-LYRVHEFSKVEMFVVSTP--EQSAAELDYLVEVQKGTFQALGVHCRQLEMPSEELGASAARKF 343

  Fly   379 DLEAWFGGSGAYRELVSCSNCLDYQARRLLVRFGQTKKMNAAVDYVHMLNATMCAATRVICAILE 443
            |:|||..|...|.|:.|.|||.|:|:|||.:::   |..:....|.|..|.|..|:||.:.::||
 Worm   344 DIEAWMPGRKLYGEVSSASNCTDFQSRRLGIKY---KTADGTTKYAHTCNGTALASTRALISVLE 405

  Fly   444 THQTE-TGI-KVPEPLKKYM-----PAKFQ 466
            |.|.: .|: ::||||:|.:     |.:||
 Worm   406 TFQNDKKGLGELPEPLRKRVKQRGSPLRFQ 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SerRS	NP_608743.2	PLN02678	3..476	CDD:215364	133/485 (27%)
sars-2	NP_500549.1	class_II_aaRS-like_core	131..423	CDD:444800	97/318 (31%)