Protein Alignment CG17258 and LOC1277724

DIOPT Version :10

• Sequence 1: NP_608742.2
• Gene: CG17258 / 33517
• FlyBaseID: FBgn0031496
• Length: 876
• Species: Drosophila melanogaster
• Sequence 2: XP_317210.4
• Gene: LOC1277724 / 1277724
• VectorBaseID: AGAMI1_013197
• Length: 900
• Species: Anopheles gambiae
• Alignment Length: 932
• Identity: 301/932 - (32%)
• Similarity: 476/932 - (51%)
• Gaps: 115/932 - (12%)

  Fly     7 REKPSKETRWDRIRKRHLQANPLGLKTDAVRRLIETDYVGRRQERLLIEGEDS---------KQL 62
            |:..:||:||||||::||  |.|.:.:..|::.|..|:|...|.||::.||.:         ..|
Mosquito    21 RKARAKESRWDRIRRKHL--NNLTVTSKTVKKFINMDFVDENQLRLMMAGEGAGSGTPGNGKPML 83

  Fly    63 NPGLIMDMRHKMFQKIPHK------LPLATIAHDP--SNSLEATKAHNLEVEKRFIDNQLQKFRQ 119
            :|.|:||:||:|.::...|      .|..    ||  :..||..:.||..:|....:|:|.|||:
Mosquito    84 DPVLVMDIRHEMIRRKEEKGGETRTKPFI----DPVKAYQLENLENHNRSIELTLCENELNKFRK 144

  Fly   120 QLSRQ--FQRTKSHRVPPTKPDF------KLNNGPLVKSLAQAAQHIDNFYNTPVQALSQMAQMC 176
            ||...  ....|..:|...|...      |::||.:.:||.:..::..:||.:.::...|:.:
Mosquito   145 QLEHMGGAGNGKKAQVSTQKRSILYINIPKIDNGMIYESLEECERYTTHFYQSAIEGSEQLFE-- 207

  Fly   177 SETKSEATKSLIQQ---LRAEPEKEAEADMDCEWTEQEAQVVEIPAFIEEQVISFDALEYRNFTK 238
             |.:.|....|::|   :....|:|.:.|:     |:|:..|| |.|......|..|:||.....
Mosquito   208 -EIQDERPLGLVKQTATIEEIIEREEQEDI-----EKESATVE-PIFGALDGPSNGAVEYAPNGV 265

  Fly   239 QVQADESKA-------KLLRCRTPSPLT---STEEFFRPMRAAAERQMLHVRTVRHEEDLLQENK 293
            ..:.:|..|       |::|......:|   ....|........:...|.:.::..:.|...|.:
Mosquito   266 HHEPEEDPAEDQDEDSKIVRFGNTEVITFPADDSSFSLGSEYDFDDHDLFLESLDSDVDEFDETE 330

  Fly   294 ------------QAQQPEGEPSSLKRESSTCSNTSDGIDSVISDLAEE-----ALYELQLEAAEK 341
                        ..:...|:..||..:||.|. |...||:..|...|:     |.......|.|.
Mosquito   331 FQSTDSTADHSGANEDRSGKRDSLPTDSSECL-TISRIDTSHSGSKEDQDTSSAFSRRNRLAYEY 394

  Fly   342 ENEELDKELPVPPKLVQFQLPPKKSPTLTTHPVGDSEAEPEQEPLLIRRIELPKVVVKPKEPEL- 405
            ::||..:.|.:.|.                     :|...:.:|:::|:.:|...      .||
Mosquito   395 DDEEESELLEIAPA---------------------AEKLSKADPIVVRKCDLKDY------SELC 432

  Fly   406 ---KQPSSSSEDESDVEPTHEKQKIIEQLFQA--RANTQLVVMRKYFLKWIHFTTMEKIEREQGQ 465
               .:|.|.:..:..||.|.|.:|:|....:.  ..|....|:::||.||:.:|.:|||.:..|.
Mosquito   433 VTNYRPDSGAAKDDRVELTEESRKLISNALKEGYLQNHDRAVLKQYFFKWLQYTILEKISKGAGV 497

  Fly   466 SCQARDTRVQKINAFLDKVRQEKRRQRTETVAETSKTTQKSLEKREEAVKMAKQFKNKLKVQQDI 530
            : ..|:.::::||.|:..:|..:::....:...|..|.|.:..|        |:::::|||||||
Mosquito   498 T-STREQKLKRINDFISNIRHSRKKGALRSKPSTDSTGQPTSVK--------KEYEHRLKVQQDI 553

  Fly   531 IDLQRIKLERQERLIMQLKLSKLSDEAKEAREDLKQELKTVIRCGDPKAKAKAKCLQLIGNLR-- 593
            |:||::|||||||:|.:|||||.|:.:|.::.:::.||....|.|..:.:|||||:|::||::
Mosquito   554 IELQKLKLERQERIITELKLSKFSEASKISKAEIQSELLKAARTGHVRLRAKAKCIQIVGNIKAD 618

  Fly   594 DADDEEMDRLQGKALLQPRFLQHMQERATERSMRHEQARQRRAQAEAEREAAKLALEEAKRQEDE 658
            .::::||.:||.:.|:.|:||..||:||.|||.||::|::||.:.|.|||.||.|.|||||.|||
Mosquito   619 TSEEDEMRKLQAQGLMIPKFLAKMQQRALERSQRHQEAKERRMRMEKEREDAKQAAEEAKRHEDE 683

  Fly   659 EAKRLRMEVLKEKRRQEKMAKVLKERERQRFIENQRKAVEFSRKLLKRTGMEGFKRLLERKRENL 723
            ||::.|...::|||:.||:.|:::|:|||.:|.|.:.|.||....|||.||..||.||..:.||.
Mosquito   684 EARKRRYREMREKRKLEKLQKIIREQERQAWIANNQIAKEFRLLKLKRFGMHAFKLLLGIRHENE 748

  Fly   724 VKSEEFRCRLITKNSFSSWHSYSTYRQREKIIKAEICWHNILKRRALYAWILYVQNEKSKMLVAI 788
            .:|..:|.|...:..|..|...:......|...|:......|.|.|:..|.:|:..::.|:.|||
Mosquito   749 RRSIAYRRRYYKRKYFRKWWFLTNALWESKKALADGMHEYKLYRVAVRHWKMYMHEQRCKLQVAI 813

  Fly   789 DWHALRSMEHWFARWHKYSTHCRMIEDSKTRQAISHHEWHLKWKVLDCWRRLPQILKIEKETEER 853
            ||:.:|..|...:.|...:....||...|...|.||:||.|||||.:.|:||..||:||||||.|
Mosquito   814 DWYEVRMAEKVISIWIGKTKQSLMILHGKMSHAASHYEWQLKWKVFERWQRLHIILRIEKETEMR 878

  Fly   854 RQRWRMKIWELLPDYKPREDSL 875
            |||||||||||||||||.|:.:
Mosquito   879 RQRWRMKIWELLPDYKPIEEDI 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17258	NP_608742.2	DUF5401	<395..>733	CDD:375164	134/345 (39%)
LOC1277724	XP_317210.4	None