DRSC/TRiP Functional Genomics Resources

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Protein Alignment GABPI and ZDHHC18

DIOPT Version :9

Sequence 1:NP_608741.1 Gene:GABPI / 33516 FlyBaseID:FBgn0031495 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_115659.1 Gene:ZDHHC18 / 84243 HGNCID:20712 Length:388 Species:Homo sapiens


Alignment Length:385 Identity:87/385 - (22%)
Similarity:122/385 - (31%) Gaps:140/385 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    88 LPWRGGAKRISPAA-----------VAPA----------------------------------FI 107
            ||...||:|..|||           .|||                                  |.
Human    16 LPASPGARRPGPAASPTPGPGPAPPAAPAPPRWSSSGSGSGSGSGSLGRRPRRKWEVFPGRNRFY 80

  Fly   108 VPLMLGLATLNSKTAIVLMLTLVGFTIWGMELAKRTATRTNFFLSWLVFSVFYMIIIFEFQVPLL 172
            ....|.||......|:.|:|.|               |.|..|   .||...|:.......:|::
Human    81 CGGRLMLAGHGGVFALTLLLIL---------------TTTGLF---FVFDCPYLARKLTLAIPII 127

  Fly   173 ELAPEENYALMFFSCAALYCLYSAKALSPLNLVSAQYGTTPKDELPGIAEASSGEEQAEAQTTLQ 237
            .       |::||  ..:.||.......|        |..|:   ..:.||::.|:|.       
Human   128 A-------AILFF--FVMSCLLQTSFTDP--------GILPR---ATVCEAAALEKQI------- 165

  Fly   238 MESVLSLDDDEVGDM----DTAERSGLMHGQP---NICEICRKVTPRRAYHCPVCGTCVKRRDHH 295
                     |..|..    ....|..|::||.   ..|..|:...|.|..||.||..||:|.|||
Human   166 ---------DNTGSSTYRPPPRTREVLINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHH 221

  Fly   296 SYWLNCCIGERNY-VWYIVGLALSEIALLLGA----NLTLTSICHPFMVVRPLGYPVLLPDDCSE 355
            ..|:..|:|.||| .:|...|:||.:...:.|    :|||.:....|:..        |.:..:.
Human   222 CPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLRAQGSNFLST--------LKETPAS 278

  Fly   356 VFEGFDLGISFVVACYALLISSYIAFILARQAYLWWKGSTLHEYKRTSNAAGRNRIWSNW 415
            |.|        :|.|:..:.|     ||....:        |.|...||......|..:|
Human   279 VLE--------LVICFFSIWS-----ILGLSGF--------HTYLVASNLTTNEDIKGSW 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GABPINP_608741.1 zf-DHHC 262..399 CDD:279823 40/144 (28%)
ZDHHC18NP_115659.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..67 11/50 (22%)
zf-DHHC 191..314 CDD:279823 41/151 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 364..388
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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