DRSC/TRiP Functional Genomics Resources

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Protein Alignment GABPI and Zdhhc17

DIOPT Version :9

Sequence 1:NP_608741.1 Gene:GABPI / 33516 FlyBaseID:FBgn0031495 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_001034429.1 Gene:Zdhhc17 / 366889 RGDID:1595790 Length:622 Species:Rattus norvegicus


Alignment Length:316 Identity:67/316 - (21%)
Similarity:119/316 - (37%) Gaps:105/316 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   106 FIVPLMLG-LATLNSKTAIVLMLTLVGFTIW-----------------GMELAKRTATRTNFFLS 152
            |:|..::| :|.||..:.::..|...|  :|                 .:.|....||:...:::
  Rat   301 FLVIWLVGFIADLNIDSWLIKGLMYGG--VWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVT 363

  Fly   153 WLVFSVFYMIIIF-EFQVPLLELAPEENYALMFFSCAALYCLYSAKALSPLNLVSAQYGTTPKDE 216
            |  |..|:..:.| ...:|.|     .|...:|::                      :|.:.|.:
  Rat   364 W--FFWFWNDLSFLSIHLPFL-----ANSVALFYN----------------------FGKSWKSD 399

  Fly   217 LPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRAYH 281
             |||.:|:   |:.:.:|.:::.        |.|.:|.:          ..|..|....|.|:.|
  Rat   400 -PGIIKAT---EEQKKKTIVELA--------ETGSLDLS----------IFCSTCLIRKPVRSKH 442

  Fly   282 CPVCGTCVKRRDHHSYWL-NC-CIGERNY-VWYIVGLALSEIALLLGANLTLTSICHPFMVVRPL 343
            |.||..|:.:.|||..|: || |.|...| :.|:..|              |..||  :|:...:
  Rat   443 CGVCNRCIAKFDHHCPWVGNCVCAGNHRYFMGYLFFL--------------LFMIC--WMIYGCV 491

  Fly   344 GYPVLLPDDCSEVF--EGFDLGISFVVAC----YALLISS-----YIAFILARQAY 388
            .|..|   .|...:  :||...|:.:..|    :.:.::|     ::|.:|..|.|
  Rat   492 SYWGL---HCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFMWVAVLLMCQMY 544

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GABPINP_608741.1 zf-DHHC 262..399 CDD:279823 36/141 (26%)
Zdhhc17NP_001034429.1 Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000250|UniProtKB:Q80TN5 1..295
Ank_4 <60..100 CDD:290365
ANK 77..192 CDD:238125
ANK repeat 79..110 CDD:293786
Ank_2 84..177 CDD:289560
ANK repeat 112..144 CDD:293786
ANK 143..267 CDD:238125
ANK repeat 146..177 CDD:293786
Ank_2 151..245 CDD:289560
ANK repeat 179..211 CDD:293786
ANK repeat 214..245 CDD:293786
zf-DHHC 428..558 CDD:279823 36/136 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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