DRSC/TRiP Functional Genomics Resources

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Protein Alignment GABPI and Zdhhc17

DIOPT Version :9

Sequence 1:NP_608741.1 Gene:GABPI / 33516 FlyBaseID:FBgn0031495 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_766142.2 Gene:Zdhhc17 / 320150 MGIID:2445110 Length:632 Species:Mus musculus


Alignment Length:310 Identity:63/310 - (20%)
Similarity:111/310 - (35%) Gaps:113/310 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   125 LMLTLVGFT-----------------IW-----------------GMELAKRTATRTNFFLSWLV 155
            |::.||||.                 :|                 .:.|....||:...:::|  
Mouse   312 LVIWLVGFIADLDIDSWLIKGLMYGGVWATVQFLSKSFFDHSMHSALPLGIYLATKFWMYVTW-- 374

  Fly   156 FSVFYMIIIFEF-QVPLLELAPEENYALMFFSCAALYCLYSAKALSPLNLVSAQYGTTPKDELPG 219
            |..|:..:.|.| .:|.|     .|...:|::                      :|.:.|.: ||
Mouse   375 FFWFWNDLNFLFIHLPFL-----ANSVALFYN----------------------FGKSWKSD-PG 411

  Fly   220 IAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRAYHCPV 284
            |.:|:   |:.:.:|.:::.        |.|.:|.:          ..|..|....|.|:.||.|
Mouse   412 IIKAT---EEQKKKTIVELA--------ETGSLDLS----------IFCSTCLIRKPVRSKHCGV 455

  Fly   285 CGTCVKRRDHHSYWLNCCIGERNYVWYIVGLALSEIALLLGANLTLTSICHPFMVVRPLGYPVLL 349
            |..|:.:.|||..|:..|:|..|: .|.:|...          ..|..||  :|:...:.|..| 
Mouse   456 CNRCIAKFDHHCPWVGNCVGAGNH-RYFMGYLF----------FLLFMIC--WMIYGCVSYWGL- 506

  Fly   350 PDDCSEVF--EGFDLGISFVVAC----YALLISS-----YIAFILARQAY 388
              .|...:  :||...|:.:..|    :.:.::|     ::|.:|..|.|
Mouse   507 --HCETTYTKDGFWTYITQIATCSPWMFWMFLNSVFHFLWVAVLLMCQLY 554

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GABPINP_608741.1 zf-DHHC 262..399 CDD:279823 34/138 (25%)
Zdhhc17NP_766142.2 Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000269|PubMed:25253725 11..305
ANK repeat 89..120 CDD:293786
PHA03095 100..>352 CDD:222980 6/39 (15%)
ANK repeat 122..154 CDD:293786
ANK repeat 156..187 CDD:293786
Ank_2 161..255 CDD:372319
ANK repeat 189..221 CDD:293786
ANK repeat 224..255 CDD:293786
DHHC 438..568 CDD:366691 34/133 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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