Protein Alignment GABPI and ZDHHC22

DIOPT Version :10

• Sequence 1: NP_608741.1
• Gene: GABPI / 33516
• FlyBaseID: FBgn0031495
• Length: 420
• Species: Drosophila melanogaster
• Sequence 2: NP_777636.2
• Gene: ZDHHC22 / 283576
• HGNCID: 20106
• Length: 263
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 66/270 - (24%)
• Similarity: 98/270 - (36%)
• Gaps: 70/270 - (25%)

  Fly   159 FYMIIIFEFQVPLLELAP---EENYALMFFSCA----ALYCLYSAKALSPLNLVSAQYGTTPKDE 216
            |..|.:..|.:.|....|   |:..|...||.|    ||:...||.||....||   ...:| |:
Human    15 FLCISLVTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLFLSANALGNYVLV---IQNSP-DD 75

  Fly   217 LPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRAYH 281
            |.....||:.:....:.:|                              :.|.:|.:||
Human    76 LGACQGASARKTPCPSPST------------------------------HFCRVCARVT------ 104

  Fly   282 CPVCGTCVKRRDHHSYWLNCCIGERNYVWYIVGLALSEIALL--LGANLTLTSICHPFMVVRPLG 344
                    .|.|||.::...|||.||...:::....:.:|.|  :.|.:...|.........||.
Human   105 --------LRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFAHPLA 161

  Fly   345 YPVLLPDDCSEVFEGFDLGIS-FVVACYALLISSYIAFILA------RQAYLWWKGSTLHEYKRT 402
            :..|||...|:.|.|..||.. ||:    |::..:.|..||      .|..|..:|.|.|:.::
Human   162 FLTLLPTSISQFFSGAVLGSEMFVI----LMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRK- 221

  Fly   403 SNAAGRNRIW 412
             ..|.|.|.|
Human   222 -GVAVRARPW 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GABPI	NP_608741.1	DHHC	262..399	CDD:396215	38/145 (26%)
ZDHHC22	NP_777636.2	DHHC	92..218	CDD:396215	38/173 (22%)