DRSC/TRiP Functional Genomics Resources

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Protein Alignment GABPI and ZDHHC22

DIOPT Version :9

Sequence 1:NP_608741.1 Gene:GABPI / 33516 FlyBaseID:FBgn0031495 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_001351101.1 Gene:ZDHHC22 / 283576 HGNCID:20106 Length:263 Species:Homo sapiens


Alignment Length:270 Identity:66/270 - (24%)
Similarity:98/270 - (36%) Gaps:70/270 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   159 FYMIIIFEFQVPLLELAP---EENYALMFFSCA----ALYCLYSAKALSPLNLVSAQYGTTPKDE 216
            |..|.:..|.:.|....|   |:..|...||.|    ||:...||.||....||   ...:| |:
Human    15 FLCISLVTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLFLSANALGNYVLV---IQNSP-DD 75

  Fly   217 LPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRAYH 281
            |.....||:.:....:.:|                              :.|.:|.:||      
Human    76 LGACQGASARKTPCPSPST------------------------------HFCRVCARVT------ 104

  Fly   282 CPVCGTCVKRRDHHSYWLNCCIGERNYVWYIVGLALSEIALL--LGANLTLTSICHPFMVVRPLG 344
                    .|.|||.::...|||.||...:::....:.:|.|  :.|.:...|.........||.
Human   105 --------LRHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYISAVLSISFAHPLA 161

  Fly   345 YPVLLPDDCSEVFEGFDLGIS-FVVACYALLISSYIAFILA------RQAYLWWKGSTLHEYKRT 402
            :..|||...|:.|.|..||.. ||:    |::..:.|..||      .|..|..:|.|.|:.:: 
Human   162 FLTLLPTSISQFFSGAVLGSEMFVI----LMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRK- 221

  Fly   403 SNAAGRNRIW 412
             ..|.|.|.|
Human   222 -GVAVRARPW 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GABPINP_608741.1 zf-DHHC 262..399 CDD:279823 38/145 (26%)
ZDHHC22NP_001351101.1 DHHC 92..218 CDD:366691 38/173 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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