DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GABPI and Zdhhc19

DIOPT Version :9

Sequence 1:	NP_608741.1	Gene:	GABPI / 33516	FlyBaseID:	FBgn0031495	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_955013.1	Gene:	Zdhhc19 / 245308	MGIID:	2682948	Length:	347	Species:	Mus musculus

Alignment Length:	253	Identity:	61/253 - (24%)
Similarity:	92/253 - (36%)	Gaps:	63/253 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 LSWLVFSVFYMIIIFEFQVPLLELAPEENYALMFFSCAALYCLYSAKALSP-----------LNL 204
            |||...|||     ..|.|.||..     .:.:||.....:.:.:.:...|           .:|
Mouse    22 LSWFPSSVF-----AAFNVTLLLF-----LSGLFFGFPCRWLVQNGEWAFPAITGPLFILTFFSL 76

  Fly   205 VSAQYGTTPKDELPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICE 269
            ||..:..      |||....|.:|                |...|..:...:|:..:..    |.
Mouse    77 VSLNFSD------PGILHRGSTKE----------------DPMTVHVVRVNQRAFRLEW----CP 115

  Fly   270 ICRKVTPRRAYHCPVCGTCVKRRDHHSYWLNCCIGERN---YVWYIVGLALSEIALLLGANLTLT 331
            .|....|.|.||||.|..||:..|||..|:|.|||.||   ::..::.|.|...|||:.....|.
Mouse   116 KCLFHRPPRTYHCPWCNICVEDFDHHCKWVNNCIGHRNFRLFMLLVLSLCLYSGALLVTCLTFLF 180

  Fly   332 SICH-PFMVVRPLGYPVLLPDDCSEVFEGFDLGISFVVACYALLISSYIAFILARQAY 388
            ...| ||.:.:.:...|.:|            ...|::..:.||:...::...|..:|
Mouse   181 RTRHLPFSLDKGMAILVAVP------------AAGFLIPLFLLLLIQALSVSRAESSY 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GABPI	NP_608741.1	zf-DHHC	262..399	CDD:279823	37/131 (28%)
Zdhhc19	NP_955013.1	DHHC	109..>181	CDD:366691	27/75 (36%)
Zdhhc19	NP_955013.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..347
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810