DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GABPI and Zdhhc5

DIOPT Version :9

Sequence 1:	NP_608741.1	Gene:	GABPI / 33516	FlyBaseID:	FBgn0031495	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	NP_659136.1	Gene:	Zdhhc5 / 228136	MGIID:	1923573	Length:	715	Species:	Mus musculus

Alignment Length:	249	Identity:	65/249 - (26%)
Similarity:	89/249 - (35%)	Gaps:	56/249 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 VFSVFYMIIIFEFQVPLLEL-----APEENYALMFFSCAALYCLYSAKALSPLNLVSAQYGTTPK 214
            :|.|....:.|.|..|.|.|     .|..| |:||....|.:.:                 .|..
Mouse    22 IFLVGATTLFFAFTCPGLSLNVSPAVPIYN-AIMFLFVLANFSM-----------------ATFM 68

  Fly   215 DELPGIAEASSGEEQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEICRKVTPRRA 279
            |  |||...:..:|..|             ||.......|.|..|: ..:...|..||...|.|.
Mouse    69 D--PGIFPRAEEDEDKE-------------DDFRAPLYKTVEIKGI-QVRMKWCATCRFYRPPRC 117

  Fly   280 YHCPVCGTCVKRRDHHSYWLNCCIGERNYVWYIVGLALSEIALLLGANLTLTSICHPFMVVRPLG 344
            .||.||..||:..|||..|:|.|||.|||.::.:.| ||..|.::|.                .|
Mouse   118 SHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFL-LSLTAHIMGV----------------FG 165

  Fly   345 YPVLLPDDCSEVFEGFDLGISFVVACYALLISSYIAFILARQAYLWWKGSTLHE 398
            :.:|......|...|....::..|.|.|.|....:|.:......|..:|.|.:|
Mouse   166 FGLLYVLYHIEELSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNE 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GABPI	NP_608741.1	zf-DHHC	262..399	CDD:279823	40/137 (29%)
Zdhhc5	NP_659136.1	zf-DHHC	99..224	CDD:279823	40/139 (29%)
Zdhhc5	NP_659136.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	289..715
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810