DRSC/TRiP Functional Genomics Resources

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Protein Alignment GABPI and dhhc-14

DIOPT Version :9

Sequence 1:NP_608741.1 Gene:GABPI / 33516 FlyBaseID:FBgn0031495 Length:420 Species:Drosophila melanogaster
Sequence 2:NP_001024514.2 Gene:dhhc-14 / 181109 WormBaseID:WBGene00044071 Length:565 Species:Caenorhabditis elegans


Alignment Length:356 Identity:79/356 - (22%)
Similarity:136/356 - (38%) Gaps:120/356 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 EYVAEDSRERSHILGCCCNCVDFDLVCTRLVTCRAID---RRNIDG---MLIAFQDRLRLPWRGG 93
            ||..:.|..........|....|.:...||:.....|   :.:..|   :.:|.|||        
 Worm   147 EYAKDISDNSGMTPAMMCAKRSFTMFPLRLIVRAGADLSLKEHFSGNTALHLAAQDR-------- 203

  Fly    94 AKRISPAAVAPAFIVPLMLGLATLN-----SKTAIVLMLTLVGFTIWGM--ELAKRT-ATRTN-- 148
                :.:||     :.|:.|.|.:|     |:|.:.:..|:....|..:  :.|:|. .:||:  
 Worm   204 ----NSSAV-----MELLEGNANVNIRNKQSETPLDMARTIKSPQILDLMEDAARRQGVSRTSCF 259

  Fly   149 --------------------FFLSWLVFS---------------VFYMIII-FEFQVPLLELAPE 177
                                ||:::|:|.               :|.|::| |::..|..:|.| 
 Worm   260 RRSFVPPISTYFFFLVPMFGFFMTYLLFKYLPLIIATFSTLISCIFLMVLIRFDYHDPTYKLLP- 323

  Fly   178 ENYA-------LMFFSCAAL---YCLYSAKALSPLNLVSAQY-----GTTPKDELPGIAEASSGE 227
              |.       ||..|.:|.   |..:.|:.|..|::::..:     ||..    ||:..|:...
 Worm   324 --YGVTIAEAILMVLSWSAYAHWYVPWWAQMLFVLSVLALAFTLFRIGTLD----PGVVRAAKNC 382

  Fly   228 EQAEAQTTLQMESVLSLDDDEVGDMDTAERSGLMHGQPNICEIC--RKVTPRRAYHCPVCGTCVK 290
            .|            |.:::.|         :|:.| |...|..|  ||:...:  ||.|||.||.
 Worm   383 HQ------------LFVNEAE---------AGIQH-QQKYCFTCFIRKMDHTK--HCAVCGFCVN 423

  Fly   291 RRDHHSYWLNCCIGERN---YVWYIVGLALS 318
            ..|||..|||.|:..||   ::.:::.:::|
 Worm   424 NFDHHCPWLNSCVTRRNMREFIMFVISVSVS 454

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GABPINP_608741.1 zf-DHHC 262..399 CDD:279823 23/62 (37%)
dhhc-14NP_001024514.2 ANK 19..143 CDD:238125
Ank_2 30..120 CDD:289560
ANK repeat 55..87 CDD:293786
ANK repeat 89..120 CDD:293786
Ank_2 94..222 CDD:289560 19/91 (21%)
ANK 117..244 CDD:238125 23/113 (20%)
ANK repeat 190..222 CDD:293786 11/48 (23%)
PulO <261..>367 CDD:224900 20/108 (19%)
zf-DHHC 394..521 CDD:279823 23/64 (36%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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