Protein Alignment Prp40 and URN1

DIOPT Version :10

• Sequence 1: NP_608738.1
• Gene: Prp40 / 33513
• FlyBaseID: FBgn0031492
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_015478.1
• Gene: URN1 / 856275
• SGDID: S000006356
• Length: 465
• Species: Saccharomyces cerevisiae
• Alignment Length: 505
• Identity: 99/505 - (19%)
• Similarity: 176/505 - (34%)
• Gaps: 159/505 - (31%)

  Fly    55 EWTEHKAPDGRPYYYNQNTKQSSWEKPEALMTPAELLHNQCPWKEYRSDT--------------- 104
            ||.|.|.|.|:.||||:|||||.||||. |...:.|..|....:..|..|
Yeast     4 EWQEFKTPAGKKYYYNKNTKQSRWEKPN-LKKGSNLESNAKESQTERKPTFSLELVNGWHLIIYN 67

  Fly   105 -GKVYYHNVATKETCWEPPPEYVDMKAKAKAEEAAAAAKAVAAMTSSSLAGMVPPAA-------- 160
             |...|.|..:||           .|.....|:.:.....:.::....|..::..|.
Yeast    68 DGTKLYFNDDSKE-----------FKNDISQEDDSRCRSLIESLDKEKLVLLIGVARGYTMREED 121

  Fly   161 LASILPAALPVAPRLPTPEIH-----------------------SPLTPS-----SNENSSSAMD 197
            :..||.:.        ..|||                       |||..|     |...|||..
Yeast   122 IDKILESC--------NEEIHLFKRNQDEVERKDEISEEAGDVKSPLQESHTGLVSGYGSSSGE- 177

  Fly   198 QAMAATLAAIEVPQQNAKKDDKSESAVVFKDKREAIESFKELLRDRNVPSNANWDQCVKIISKDP 262
                      |..:::.::|:::|..:|.:|    |....:|.|                |..|
Yeast   178 ----------EDEEEDEEEDEENEEQIVNQD----ISIIDDLNR----------------IDTD- 211

  Fly   263 RYAAFKNLNERKQTFNAYKTQKIKDEREESRLKAKKAKEDLEQFLMSSDKMNSQMKYFRCEEVFA 327
                  :::||...|..:...|: |:.....|::||.:.|.:.:.:..|.:...:     .|.:.
Yeast   212 ------DIDERNIFFELFDRYKL-DKFSTWSLQSKKIENDPDFYKIRDDTVRESL-----FEEWC 264

  Fly   328 GTRTWTA-VPEPDRRDIYEDCIFNLAKREKEEARLLKKRNMKVLGELLESMTSINHATTWSEAQ- 390
            |.|:..| ..|.|..|..||           ::.:|:......|.:::.:..:|...|...:.:
Yeast   265 GERSGNATAEESDSEDNSED-----------DSEVLEPTKYHYLAQIVANAGTIAPDTIPQDIRK 318

  Fly   391 --------VMLLDNVAFKNDVTLLGMDKEDALIVFEEHIRTLEKEEDEE------REREKK---- 437
                    ..:.:.:..|.|     .||..:.::|  :.:|.:.|:.:|      |:.|:.
Yeast   319 QQKALYKAYKIKEYIPSKRD-----QDKFVSQLLF--YYKTFDLEQRKEIFCDCLRDHERDFTGA 376

  Fly   438 -RMKRQQRKNRDSFLALLDSLHEEGKLTSMSLWVE----LYPIISADLRF 482
             ...||.::..|.:..||.:..:...:..:.|.:|    :.||:..:.|:
Yeast   377 VESLRQDKELIDRWQTLLKAPADSSSIEDILLSIEHRCCVSPIVVTEPRY 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp40	NP_608738.1	PRP40	54..634	CDD:227435	99/505 (20%)
URN1	NP_015478.1	PRP40	2..>88	CDD:227435	30/95 (32%)
		WW	5..30	CDD:459800	16/24 (67%)
		FF	219..263	CDD:426471	9/49 (18%)