Protein Alignment Prp40 and PRP40A

DIOPT Version :10

• Sequence 1: NP_608738.1
• Gene: Prp40 / 33513
• FlyBaseID: FBgn0031492
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: NP_175113.2
• Gene: PRP40A / 841057
• AraportID: AT1G44910
• Length: 958
• Species: Arabidopsis thaliana
• Alignment Length: 891
• Identity: 272/891 - (30%)
• Similarity: 422/891 - (47%)
• Gaps: 135/891 - (15%)

  Fly     2 NVPPSVGNGGAPPGRGIGYTPPGAIVPQFPPPGF----------GAPP----------------- 39
            |.||..|...:.|.....||...:..||..|...          |.||
plant    98 NAPPMTGFATSGPPFSSPYTFVPSSYPQQQPTSLVQPNSQMHVAGVPPAANTWPVPVNQSTSLVS 162

  Fly    40 PPELAAAFGVMATST-----------EWTEHKAPDGRPYYYNQNTKQSSWEKPEALMTPAELLHN 93
            |.:.......:|.||           :|.||.:.|||.||||:.||||:||||..||||.|....
plant   163 PVQQTGQQTPVAVSTDPGNLTPQSASDWQEHTSADGRKYYYNKRTKQSNWEKPLELMTPLERADA 227

  Fly    94 QCPWKEYRSDTGKVYYHNVATKETCWEPPPEYVDMK----------AKAKAEEAAAAAKAVAAMT 148
            ...|||:.:..||.||:|..|||:.|..|.   |:|          .|....||.:...:..|.:
plant   228 STVWKEFTTPEGKKYYYNKVTKESKWTIPE---DLKLAREQAQLASEKTSLSEAGSTPLSHHAAS 289

  Fly   149 SSSLA-----GMVPPAALASILPAALPVAPRLPTPEIH----SPLTPSS--------------NE 190
            ||.||     .:||..:.|....::.|:...|..|...    :|:||:|              |.
plant   290 SSDLAVSTVTSVVPSTSSALTGHSSSPIQAGLAVPVTRPPSVAPVTPTSGAISDTEATTIKGDNL 354

  Fly   191 NSSSAMDQAMAATLAAIEVPQQ----NAKKD-----DKS--ESAVVFKDKREAIESFKELLRDRN 244
            :|..|.|....||....|...:    |.|.:     ||:  |..:|:..|:||..:||.||...|
plant   355 SSRGADDSNDGATAQNNEAENKEMSVNGKANLSPAGDKANVEEPMVYATKQEAKAAFKSLLESVN 419

  Fly   245 VPSNANWDQCVKIISKDPRYAAFKNLNERKQTFNAYKTQKIKDEREESRLKAKKAKEDLEQFLMS 309
            |.|:..|:|.:|.|..|.||.|.:.|.||||.||.|..|:.|.|.||.|.:.|||:|:..:.|..
plant   420 VHSDWTWEQTLKEIVHDKRYGALRTLGERKQAFNEYLGQRKKVEAEERRRRQKKAREEFVKMLEE 484

  Fly   310 SDKMNSQMKYFRCEEVFAGTRTWTAVPEP-DRRDIYEDCIFNLAKREKEEARLLKKRNMKVLGEL 373
            .::::|.:|:.:...:|...:.:.||..| ||.|::::.|..|.::|:|:|....::.|....:.
plant   485 CEELSSSLKWSKAMSLFENDQRFKAVDRPRDREDLFDNYIVELERKEREKAAEEHRQYMADYRKF 549

  Fly   374 LESMTSINHATTWSEAQVMLLDNVAFKNDVTLLGMDKEDALIVFEEHIRTLEKEEDEEREREKKR 438
            ||:...|...|.|.:.|..|.|      |.....::|.|.||.|||:|..|||||:|.:..||:.
plant   550 LETCDYIKAGTQWRKIQDRLED------DDRCSCLEKIDRLIGFEEYILDLEKEEEELKRVEKEH 608

  Fly   439 MKRQQRKNRDSFLALLDSLHEEGKLTSMSLWVELYPIISADL-RFSAMLGQ-SGSTPLDLFKFYV 501
            ::|.:|||||:|..||:.....|.||:.:.|:: |.|...|| ::.|:... |||||.|||:...
plant   609 VRRAERKNRDAFRTLLEEHVAAGILTAKTYWLD-YCIELKDLPQYQAVASNTSGSTPKDLFEDVT 672

  Fly   502 ENLKARFHDEKKIIREILKEKAFVVQAKTSFEDFATVVCEDKRSASLDAGNVKLTYNSLLEKAEA 566
            |.|:.::|::|..:::.:|.:...:.:...||||.:.:.||..:..:...|:||.|:.|:.:.
plant   673 EELEKQYHEDKSYVKDAMKSRKISMVSSWLFEDFKSAISEDLSTQQISDINLKLIYDDLVGRV-- 735

  Fly   567 IEKERMKEEVRRLRKLENEIKNEWLEA--NVSVAEPYESAKKLVEHLEAFALYEKEIGVEKI--- 626
              ||:.::|.|:|::|..|..| .|..  .::||..:|.:|:|||..:.:    :.||.|.:
plant   736 --KEKEEKEARKLQRLAEEFTN-LLHTFKEITVASNWEDSKQLVEESQEY----RSIGDESVSQG 793

  Fly   627 -WEDFV-----KESEDACSHHHSRSRKSK-KNKKHKKRVRSVSRSDIENEHIEVEKSKRRRSKTR 684
             :|:::     |..|........:.||.| :::|.|::.:...|.:.|.|. |.||.|.|..:..
plant   794 LFEEYITSLQEKAKEKERKRDEEKVRKEKERDEKEKRKDKDKERREKERER-EKEKGKERSKREE 857

  Fly   685 SHSLTSIGSIESEKLLKKKKK---RKNKLR-GSSCESDVPGIQSPGTQALLQNDSNSH-SPAKKK 744
            |...|::...|..|..|:|.|   ||::.| .::.:.||...:....::  :..|..| :..||.
plant   858 SDGETAMDVSEGHKDEKRKGKDRDRKHRRRHHNNSDEDVSSDRDDRDES--KKSSRKHGNDRKKS 920

  Fly   745 KKEKRAKKDKRHNRHNRSGTPLSPAQSVESS-GSRNEELTLSDGEL 789
            :|...:.:.:..|||.|        |..||| .|.|:|  |.|||:
plant   921 RKHANSPESESENRHKR--------QKKESSRRSGNDE--LEDGEV 956

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp40	NP_608738.1	PRP40	54..634	CDD:227435	210/648 (32%)
PRP40A	NP_175113.2	PRK10263	<71..>336	CDD:236669	70/240 (29%)
		PRP40	185..810	CDD:227435	210/643 (33%)