Protein Alignment Prp40 and Prp40

DIOPT Version :10

• Sequence 1: NP_608738.1
• Gene: Prp40 / 33513
• FlyBaseID: FBgn0031492
• Length: 806
• Species: Drosophila melanogaster
• Sequence 2: XP_061517309.1
• Gene: Prp40 / 1277723
• VectorBaseID: AGAMI1_006491
• Length: 912
• Species: Anopheles gambiae
• Alignment Length: 933
• Identity: 524/933 - (56%)
• Similarity: 640/933 - (68%)
• Gaps: 148/933 - (15%)

  Fly     1 MNVPPSVGNGGAPPGRGIGYTPPGAIVPQF--PPPGFGAP------------------------- 38
            |:|||..  .|.|      |.||  :|..|  ||||||||
Mosquito     1 MSVPPIA--TGQP------YAPP--LVSHFNIPPPGFGAPGGGAGIGGPVALAAAAAANGTMVDP 55

  Fly    39 ----PPPELAAAFGVMATS-------------TEWTEHKAPDGRPYYYNQNTKQSSWEKPEALMT 86
                ||...|.|.|..|.:             .||:|||.|:||.||||..||||.||||:.:.|
Mosquito    56 TATVPPVIPAGAAGAAAAAVAAAAVPVTTAIVNEWSEHKTPEGRTYYYNSITKQSLWEKPDEMKT 120

  Fly    87 PAELLHNQCPWKEYRSDTGKVYYHNVATKETCWEPPPEYVDMKAKAKAEEAAA-AAKAVAAMTSS 150
            |||...:||||||||||:||:||||.||||:.|..||||:::|.|..||:||| ||||.|..||:
Mosquito   121 PAEKQLSQCPWKEYRSDSGKLYYHNTATKESQWVAPPEYLELKEKVAAEQAAAEAAKAAALKTSA 185

  Fly   151 SLAGM---------VPPA-----ALASILPAALPVAPRLPTP---EIHSPLTPSSNENSSSAMDQ 198
            ..:.|         |.||     |.|.:.|.|:..|.....|   ...:.:||.|.||||||:||
Mosquito   186 MASSMLMQSVVLPVVSPALAGTPATAGVAPNAVVAATAADVPLGLGGMAGVTPGSAENSSSALDQ 250

  Fly   199 AMAATLAAIEVPQQ--NAKKDDKS-------ESAVVFKDKREAIESFKELLRDRNVPSNANWDQC 254
            ||||||||||||..  :.::|::|       |.|:.||||:||||:|||.|::||:||:::|:||
Mosquito   251 AMAATLAAIEVPDDPVDKRQDEESQPGQTDEEPAMEFKDKKEAIEAFKEFLKERNIPSSSSWEQC 315

  Fly   255 VKIISKDPRYAAFKNLNERKQTFNAYKTQKIKDEREESRLKAKKAKEDLEQFLMSSDKMNSQMKY 319
            ||||.|||::..||.|:|:||.||||||||:||||||.|||||::||:||:||||||||||.:|:
Mosquito   316 VKIIQKDPKFNVFKKLSEKKQAFNAYKTQKLKDEREEQRLKAKRSKEELEKFLMSSDKMNSALKF 380

  Fly   320 FRCEEVFAGTRTWTAVPEPDRRDIYEDCIFNLAKREKEEARLLKKRNMKVLGELLESMTSINHAT 384
            :||:|:||....|.:|||.||||||||||||||||||||||::|||||:|||||||:||::.:.|
Mosquito   381 YRCDELFANLDVWKSVPEQDRRDIYEDCIFNLAKREKEEARVMKKRNMRVLGELLEAMTTVTYQT 445

  Fly   385 TWSEAQVMLLDNVAFKNDVTLLGMDKEDALIVFEEHIRTLEKEEDEEREREKKRMKRQQRKNRDS 449
            ||||||||||||.:|||||.||||||||||||||||||.||:|||||:||||||:|||||||||.
Mosquito   446 TWSEAQVMLLDNASFKNDVNLLGMDKEDALIVFEEHIRGLEREEDEEKEREKKRLKRQQRKNRDQ 510

  Fly   450 FLALLDSLHEEGKLTSMSLWVELYPIISADLRFSAMLGQSGSTPLDLFKFYVENLKARFHDEKKI 514
            ||||||:||||||||||||||||||:|||||||||||||.|||||||||||||||||||||||||
Mosquito   511 FLALLDTLHEEGKLTSMSLWVELYPLISADLRFSAMLGQPGSTPLDLFKFYVENLKARFHDEKKI 575

  Fly   515 IREILKEKAFVVQAKTSFEDFATVVCEDKRSASLDAGNVKLTYNSLLEKAEAIEKERMKEEVRRL 579
            |:||||||.|:|...|:|||||||||||||||:|||||||||||||||||.|.||||:|||.||:
Mosquito   576 IKEILKEKEFIVVRTTTFEDFATVVCEDKRSATLDAGNVKLTYNSLLEKAVAAEKERLKEETRRI 640

  Fly   580 RKLENEIKNEWLEANVSVAEPYESAKKLVEHLEAFALYEKEIGVEKIWEDFVKESEDACSHHHSR 644
            ||||||:|..|:||.:|..:.:|:|:|||...|.:.|||||..||::|||||||:||:|||||||
Mosquito   641 RKLENELKGVWIEAGLSGVDSWETAQKLVMDREVYDLYEKEDKVERLWEDFVKETEDSCSHHHSR 705

  Fly   645 SRKSKKNKKHKKRVRSVSRSDIENEHIEVEK---SKRRRSKTRSHSLTSIGSIESE--------- 697
            |:||||::||||:.||.|:|..|...:|.||   .|:|||::|: .||:....|||
Mosquito   706 SKKSKKSRKHKKKSRSSSKSLSEASEVEYEKPSSKKKRRSRSRT-PLTASDLSESEHELHEEPLH 769

  Fly   698 -----------KLLKKKKKRKNKLRGSSCESDVPGIQSPGTQALLQNDSN--------------- 736
                       :|.:|:||:|...|..|        :||..:.:|..:.|
Mosquito   770 HHNDHHGGGGDRLDRKRKKKKKHHRKQS--------RSPSYEEMLVMEKNGGGGGGGVGAAAAAS 826

  Fly   737 -SHSPA----KKKKKEKRAKKDKRHNRHNRSGTPLSPAQSVES---------SGSRN----EELT 783
             |.:|:    |||||:.:.|||||  |.:||.:..|....:.|         .|||:    ::..
Mosquito   827 RSRTPSPEVEKKKKKKDKKKKDKR--RTSRSVSRASSGARIRSPLDEGRRSRGGSRSSKMADDAA 889

  Fly   784 LSDGELESKRAALLAQLSEQLDE 806
            ||:.||||:||||||||:||:||
Mosquito   890 LSESELESQRAALLAQLNEQMDE 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp40	NP_608738.1	PRP40	54..634	CDD:227435	413/606 (68%)
Prp40	XP_061517309.1	None