DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha4GT1 and A4galt

DIOPT Version :9

Sequence 1:	NP_608737.1	Gene:	alpha4GT1 / 33512	FlyBaseID:	FBgn0031491	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	NP_071576.1	Gene:	A4galt / 63888	RGDID:	621583	Length:	360	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	103/308 - (33%)
Similarity:	156/308 - (50%)	Gaps:	29/308 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 ADPKPS-PGNSIFFHETSCRLSENRQLETLKVTARQACAIESAAMHNPNFQVFVLFAG-PTYRIS 128
            |.|:.| ||| |||.|||.|.:.:...         .|::||||..:|..||.||..| |    .
  Rat    76 AFPRVSAPGN-IFFLETSDRTNPSFLF---------MCSVESAARAHPESQVVVLMKGLP----R 126

  Fly   129 NNKSHPQPLLEAILS-YSNVHLRRLNLESYASGTPMEEWLKDGRLSRSKYLFSHISDFLRYLTLY 192
            :..:.|:.|..::|| :.||.:|.|:|:.....||:..|..:.:.....||...:||..|...|:
  Rat   127 DTTAWPRNLGISLLSCFPNVQIRPLDLQELFEDTPLAAWYLEAQHRWEPYLLPVLSDASRIALLW 191

  Fly   193 RYGGLYLDMDVVVLRNMEKVPPNYTGAESNTHLAAGVMNLAATGF--GHEIAASCLRDFQHNFNG 255
            ::||:|||.|.:||:|:..: .|..|.:|..     |:|.|...|  .||..|.|:|||..::||
  Rat   192 KFGGIYLDTDFIVLKNLRNL-TNMLGIQSRY-----VLNGAFLAFERKHEFLALCIRDFVAHYNG 250

  Fly   256 GDWGNNGPGVITRVAQKICGTKDIALMREDPKRCMGFKVFGRGAFYAVPWKQWRDFFEPENLEET 320
            ..||:.||.::|||.:|.|....:    ::.:.|.|.......|||.:||:.|:.:||..:.||.
  Rat   251 WIWGHQGPQLLTRVFKKWCSIHSL----KESRACRGVTALPPEAFYPIPWQNWKKYFEDVSPEEL 311

  Fly   321 IARCKDSYVVHVWNKHSSKLPIKIGSKNAYALYAEQNCPRSYKAAGEY 368
            ......:|.||||||.|....::..|:...|....:.||.:::|...|
  Rat   312 AQLLNATYAVHVWNKKSQGTHLEATSRALLAQLHARYCPTTHRAMTMY 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha4GT1	NP_608737.1	Gly_transf_sug	99..217	CDD:282357	40/119 (34%)
alpha4GT1	NP_608737.1	Gb3_synth	239..365	CDD:282437	42/125 (34%)
A4galt	NP_071576.1	Gly_transf_sug	98..221	CDD:282357	42/136 (31%)
		DXD motif	199..201		1/1 (100%)
		Gb3_synth	234..356	CDD:282437	42/125 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349195
Domainoid	1	1.000	92	1.000	Domainoid score	I7424
eggNOG	1	0.900	-	-		E1_KOG1928
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9690
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4247
OMA	1	1.010	-	-		QHG47281
OrthoDB	1	1.010	-	-		D1082380at2759
OrthoFinder	1	1.000	-	-		FOG0000423
OrthoInspector	1	1.000	-	-		mtm8928
orthoMCL	1	0.900	-	-		OOG6_104694
Panther	1	1.100	-	-	O	PTHR12042
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X281
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810