Protein Alignment alpha4GT1 and A4GNT

DIOPT Version :9

• Sequence 1: NP_608737.1
• Gene: alpha4GT1 / 33512
• FlyBaseID: FBgn0031491
• Length: 369
• Species: Drosophila melanogaster
• Sequence 2: NP_057245.1
• Gene: A4GNT / 51146
• HGNCID: 17968
• Length: 340
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 86/356 - (24%)
• Similarity: 155/356 - (43%)
• Gaps: 44/356 - (12%)

  Fly    12 RMFIILVLMVIGGLFYIYTSENKYHSCFMEGQVLATQQALTADGETNLLGDVLQADPKPSPGNSI 76
            ::.:.:.|:::.|..|.:|.::   ||........:.|.|.|     ||          |....|
Human     6 QLSLSVTLLLVCGFLYQFTLKS---SCLFCLPSFKSHQGLEA-----LL----------SHRRGI 52

  Fly    77 FFHETSCRLSENRQLETLKVTARQACAIESAAMHNPNFQVFVLFAGPTYRISNNKSHPQPLLEAI 141
            .|.|||.|:.....:         :|::||||...|.:.|.....|.|.......:...|....:
Human    53 VFLETSERMEPPHLV---------SCSVESAAKIYPEWPVVFFMKGLTDSTPMPSNSTYPAFSFL 108

  Fly   142 LSYSNVHLRRLNLESYASGTPMEEWLKDGRLSRSKYLFSHISDFLRYLTLYRYGGLYLDMDVVVL 206
            .:..||.|..|:::.....||:..|......|..:......||..|...:::|||:|:|.||:.:
Human   109 SAIDNVFLFPLDMKRLLEDTPLFSWYNQINASAERNWLHISSDASRLAIIWKYGGIYMDTDVISI 173

  Fly   207 RNMEKVPPNYTGAESNTHLAAGVMNLAATGF--GHEIAASCLRDFQHNFNGGDWGNNGPGVITRV 269
            |.:.:  .|:..|:::.:.:.|:.     ||  .|.....|:.:|..::|...|||.||.::||:
Human   174 RPIPE--ENFLAAQASRYSSNGIF-----GFLPHHPFLWECMENFVEHYNSAIWGNQGPELMTRM 231

  Fly   270 AQKICGTKDIALMREDPKRCMGFKVFGRGAFYAVPWKQWRDFFEPENLEETIARCKDSYVVHVWN 334
            .:..|..:|...:.:  .||:.........||.:.:::||.::|..:.|.:.   ..||.:|:||
Human   232 LRVWCKLEDFQEVSD--LRCLNISFLHPQRFYPISYREWRRYYEVWDTEPSF---NVSYALHLWN 291

  Fly   335 KHSSKLPIKIGSKNAYA--LYAEQNCPRSYK 363
            ..:.:....|...|...  || .::|||:|:
Human   292 HMNQEGRAVIRGSNTLVENLY-RKHCPRTYR 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alpha4GT1	NP_608737.1	Gly_transf_sug	99..217	CDD:282357	30/117 (26%)
		Gb3_synth	239..365	CDD:282437	34/127 (27%)
A4GNT	NP_057245.1	Gly_transf_sug	64..182	CDD:282357	30/128 (23%)
		DXD motif. /evidence=ECO:0000250|UniProtKB:Q9JI93	167..169		1/1 (100%)
		Gb3_synth	201..321	CDD:282437	33/125 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155309
Domainoid	1	1.000	62	1.000	Domainoid score	I10334
eggNOG	1	0.900	-	-		E1_KOG1928
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4301
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47281
OrthoDB	1	1.010	-	-		D1082380at2759
OrthoFinder	1	1.000	-	-		FOG0000423
OrthoInspector	1	1.000	-	-		mtm8452
orthoMCL	1	0.900	-	-		OOG6_104694
Panther	1	1.100	-	-	LDO	PTHR12042
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X281
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770