DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha4GT1 and A4galt

DIOPT Version :9

Sequence 1:	NP_608737.1	Gene:	alpha4GT1 / 33512	FlyBaseID:	FBgn0031491	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_036015294.1	Gene:	A4galt / 239559	MGIID:	3512453	Length:	359	Species:	Mus musculus

Alignment Length:	308	Identity:	108/308 - (35%)
Similarity:	153/308 - (49%)	Gaps:	29/308 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 ADPKPS-PGNSIFFHETSCRLSENRQLETLKVTARQACAIESAAMHNPNFQVFVLFAG-PTYRIS 128
            |.|:.| ||| |||.|||.|.|.|...         .|::||||..:|..||.||..| |    .
Mouse    75 AFPRVSAPGN-IFFLETSDRTSPNFLF---------MCSVESAARAHPESQVVVLMKGLP----R 125

  Fly   129 NNKSHPQPLLEAILS-YSNVHLRRLNLESYASGTPMEEWLKDGRLSRSKYLFSHISDFLRYLTLY 192
            :..:.|:.|..::|| :.||.:|.|:|:.....||:..|..:.|.....|....:||..|...|:
Mouse   126 DTTAQPRNLGISLLSCFPNVWIRPLDLQELFEDTPLAAWYSEARHRWEPYQLPVLSDASRIALLW 190

  Fly   193 RYGGLYLDMDVVVLRNMEKVPPNYTGAESNTHLAAGVMNLAATGF--GHEIAASCLRDFQHNFNG 255
            ::||:|||.|.:||:|:..: .|..|.:|..     |:|.|...|  .||..|.||.||..|:||
Mouse   191 KFGGIYLDTDFIVLKNLLNL-TNTLGIQSRY-----VLNGAFLAFERKHEFLALCLHDFVANYNG 249

  Fly   256 GDWGNNGPGVITRVAQKICGTKDIALMREDPKRCMGFKVFGRGAFYAVPWKQWRDFFEPENLEET 320
            ..||:.||.::|||.:|.|..:.:    |....|.|.......|||.:||:.|:.:||..:.||.
Mouse   250 WIWGHQGPQLLTRVFKKWCSIQSL----EKSHACRGVTALPPEAFYPIPWQNWKKYFEDISPEEL 310

  Fly   321 IARCKDSYVVHVWNKHSSKLPIKIGSKNAYALYAEQNCPRSYKAAGEY 368
            ......:|.||||||.|....::..||...|....:.||.:::|...|
Mouse   311 TQLLNATYAVHVWNKKSQGTHLEATSKALLAQLHARYCPTTHRAMKMY 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha4GT1	NP_608737.1	Gly_transf_sug	99..217	CDD:282357	40/119 (34%)
alpha4GT1	NP_608737.1	Gb3_synth	239..365	CDD:282437	45/125 (36%)
A4galt	XP_036015294.1	Gly_transf_sug	100..220	CDD:398274	42/133 (32%)
A4galt	XP_036015294.1	Gb3_synth	233..355	CDD:398326	45/125 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845777
Domainoid	1	1.000	94	1.000	Domainoid score	I7455
eggNOG	1	0.900	-	-		E1_KOG1928
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9690
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4275
Isobase	1	0.950	-	0	Normalized mean entropy	S7577
OMA	1	1.010	-	-		QHG47281
OrthoDB	1	1.010	-	-		D1082380at2759
OrthoFinder	1	1.000	-	-		FOG0000423
OrthoInspector	1	1.000	-	-		mtm8691
orthoMCL	1	0.900	-	-		OOG6_104694
Panther	1	1.100	-	-	O	PTHR12042
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5589
SonicParanoid	1	1.000	-	-		X281
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750