DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha4GT1 and LOC100493232

DIOPT Version :9

Sequence 1:	NP_608737.1	Gene:	alpha4GT1 / 33512	FlyBaseID:	FBgn0031491	Length:	369	Species:	Drosophila melanogaster
Sequence 2:	XP_002938164.2	Gene:	LOC100493232 / 100493232	-ID:	-	Length:	331	Species:	Xenopus tropicalis

Alignment Length:	383	Identity:	102/383 - (26%)
Similarity:	167/383 - (43%)	Gaps:	87/383 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RRMFIILVLMVIGGLFYIYTSENKYHSCFMEGQVLATQQALTADGETNLLGDVLQADPKPSPGNS 75
            :::|.:|:.:.|.||.|..:.:.|........:...              ||:|      |.||.
Frog     5 KKIFAVLLFLAILGLLYKGSDKEKAFGLHFTAKFTP--------------GDIL------SVGNG 49

  Fly    76 IFFHETSCRLSENRQLETLKVTARQACAIESAAMHNPNFQVFVLFAGPTY------RISNNKSHP 134
            :.|.||:.|:.....:         .|:|||||...|:..|.....|.|.      .|...|..|
Frog    50 VMFVETTDRMEPPHLV---------LCSIESAARAYPDRPVVFFMKGLTEINSEEDEIQAKKHFP 105

  Fly   135 QPLLEAILSYSNVHLRRLNLESYASGTPMEEWLKDGRLSRSKYLFSHI-SDFLRYLTLYRYGGLY 198
                 .:|||.|:||..|.:......||:..|.:..: .:::..::|| ||..|...:|::||||
Frog   106 -----TLLSYDNIHLYPLRMGVLLKNTPLISWYEKIK-PKNEIHWTHISSDASRLALIYKFGGLY 164

  Fly   199 LDMDVVVLRNMEKVPPNYTGAESNTHLAAGVMNLAATGFGHEIAASCLRDFQHNFNGGDWGNNGP 263
            :|.|::.||.:..:  |:..|||:...:.||...|:   .|....:|:.||..|:||..||:.||
Frog   165 MDTDMISLRPVPDI--NFLAAESSQISSNGVFGFAS---HHPFIWTCMEDFVKNYNGAIWGHQGP 224

  Fly   264 GVITRVAQK--------------ICGTKDIALMREDPKRCMGFKVFGRGAFYAVPWKQWRDFFEP 314
            .:.|||.|:              :||  :|:.:  :|:|           ||.:|...|:.:||
Frog   225 ALFTRVLQERYCTLFPFEAKEDILCG--NISFL--NPER-----------FYPIPCSSWKKYFE- 273

  Fly   315 ENLEETIARCKDSYVVHVWN-----KHSSKLPIKIGSKNAYALYAEQNCPRSYKAAGE 367
              :.|.:....:||.:|::|     :|...:|   ||........:|.||.:|:|..|
Frog   274 --VWEELPVFNESYALHLFNYANRDEHKVMIP---GSNTLVEHLYQQYCPATYQAVQE 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha4GT1	NP_608737.1	Gly_transf_sug	99..217	CDD:282357	38/124 (31%)
alpha4GT1	NP_608737.1	Gb3_synth	239..365	CDD:282437	39/144 (27%)
LOC100493232	XP_002938164.2	Gly_transf_sug	62..179	CDD:303104	37/133 (28%)
LOC100493232	XP_002938164.2	Gb3_synth	200..323	CDD:282437	39/143 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9755
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4577
OMA	1	1.010	-	-		QHG47281
OrthoDB	1	1.010	-	-		D1082380at2759
OrthoFinder	1	1.000	-	-		FOG0000423
OrthoInspector	1	1.000	-	-		mtm9340
Panther	1	1.100	-	-	LDO	PTHR12042
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X281
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080