Protein Alignment Ccdc85 and Ccdc85a

DIOPT Version :9

• Sequence 1: NP_608734.2
• Gene: Ccdc85 / 33509
• FlyBaseID: FBgn0031488
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: XP_006514717.1
• Gene: Ccdc85a / 216613
• MGIID: 2445069
• Length: 578
• Species: Mus musculus
• Alignment Length: 625
• Identity: 159/625 - (25%)
• Similarity: 234/625 - (37%)
• Gaps: 272/625 - (43%)

  Fly   182 APAHSIPPRYQPPPQPA-----TGILKPHLPLKYPPDIPQLSSIYIPDSIKQQQQQQQQQQSRYL 241
            |...|.|.....|..||     ||:                      |.:.:...::..|.|:
Mouse     4 AAGGSAPAAESCPSAPAGASTPTGV----------------------DDLSKVTDEELLQWSK-- 44

  Fly   242 PAHQPGAKDMLKFVRKPDQEHPSPNASVTSSGTGIPTANGGGRLTAEQNRQLQSLVNELRALKEQ 306
                   :::::.:|:.:.|..|  |.:..|           .|..|.||:||..:.|:|.||:.
Mouse    45 -------EELIRSLRRAEAEKVS--AMLDHS-----------NLIREVNRRLQLHLGEIRGLKDI 89

  Fly   307 NQRLLDDNQELRDLCCFLDDDRQKGRKLAREWQRFGRYTASVMRQEVAAYQNKLRQLDDKQQELI 371
            ||:|.:|||||||||||||||||||::::|||||.|||||.||.:|||.|..||::|:.||:|::
Mouse    90 NQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKELEVKQEEVV 154

  Fly   372 TDNLELKELCLYLDEERAHVAAN---------ALCAGCGAATRNALRDDGDGSS-SSTNADETIT 426
            .:|:||||||:.||||:....|.         :||....:|| ..:||.||||| |||.:.::..
Mouse   155 KENMELKELCMLLDEEKGVGCAGSRCSIDSQASLCQLVASAT-PYVRDVGDGSSTSSTGSTDSPD 218

  Fly   427 ALRNYA-----EQRQ-------------------------------------------------- 436
            ..:::|     |..|
Mouse   219 HHKHHASGGSPEHLQKPRSEGSPEHTKHRSTSPEHLHKPRASGTPDHSKALKGPSPEHHKPLCKG 283

  Fly   437 LPQDLRHAHT------------------------------------------------------- 446
            .|:..||.|.
Mouse   284 SPEQQRHPHPGSSPEVLPKHVLSGSPEHFQKHRPGGSPEHTRHSGGSPEHLQKHALGGSLEHLPR 348

  Fly   447 -------------------------------------------------------LNDQTLQYVR 456
                                                                   :|:.||.|||
Mouse   349 ARGTSPEHLKQHYGASPDHKHASGSGGSGGGSREGTLRRPAQEDSSSHHRNVYSGMNESTLSYVR 413

  Fly   457 SLERRIQQLEEERTTPTAHLQQPTTPTPQATPTPTVTSAATPAKSAASPHQ----QQQQQQQHQQ 517
            .||.|::|||||...           .||||.    ..:..|.:::::..:    :.::..|..|
Mouse   414 QLEARVRQLEEENRM-----------LPQATQ----NRSQPPTRNSSNMEKGWGPRARRVLQWWQ 463

  Fly   518 QQQDI-------------VAAAAAAAAAIQLPEPIAG------RPEAVVRALQVLEVREQLERDR 563
            ..:.|             .:.|....:::..|...:|      :||.||.:|:||:|.|.::|.:
Mouse   464 GCRGIGRCLPSLPGSFRLSSGADGNNSSLNSPASFSGHTTPSQQPEPVVHSLKVLDVEETIDRQQ 528

  Fly   564 LGNLAGSALDQMDDGEKALVREMCNVVWRKLEGSPHGPAA 603
             |...|..|.:.   |||:||||||||||||     |.||
Mouse   529 -GKEYGHDLSET---EKAVVREMCNVVWRKL-----GDAA 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccdc85	NP_608734.2	DUF2216	<283..389	CDD:287229	65/105 (62%)
Ccdc85a	XP_006514717.1	CCDC85	29..202	CDD:370898	79/195 (41%)
		Retinal	<217..510	CDD:373855	33/307 (11%)
		PHA03269	217..>335	CDD:165527	7/117 (6%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	152	1.000	Domainoid score	I4302
eggNOG	1	0.900	-	-		E1_KOG3819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	196	1.000	Inparanoid score	I3802
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002221
OrthoInspector	1	1.000	-	-		otm44298
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13546
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1655
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	8.010