Protein Alignment Ccdc85 and CCDC85A

DIOPT Version :10

• Sequence 1: NP_608734.2
• Gene: Ccdc85 / 33509
• FlyBaseID: FBgn0031488
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_001335441.1
• Gene: CCDC85A / 114800
• HGNCID: 29400
• Length: 586
• Species: Homo sapiens
• Alignment Length: 637
• Identity: 161/637 - (25%)
• Similarity: 231/637 - (36%)
• Gaps: 301/637 - (47%)

  Fly   180 APAPAHSIPPRYQPPPQPATGILKPHLPLKYPPDIPQLSSIYIPDSIKQQQQQQQQQQSRYLPAH 244
            :||||.|    ...||.|                :..||.:         ..::..|.|:
Human    19 SPAPAGS----SAAPPAP----------------VEDLSKV---------SDEELLQWSK----- 49

  Fly   245 QPGAKDMLKFVRKPDQEHPSPNASVTSSGTGIPTANGGGRLTAEQNRQLQSLVNELRALKEQNQR 309
                :::::.:|:.:.|..|  |.:..|           .|..|.||:||..:.|:|.||:.||:
Human    50 ----EELIRSLRRAEAEKVS--AMLDHS-----------NLIREVNRRLQLHLGEIRGLKDINQK 97

  Fly   310 LLDDNQELRDLCCFLDDDRQKGRKLAREWQRFGRYTASVMRQEVAAYQNKLRQLDDKQQELITDN 374
            |.:|||||||||||||||||||::::|||||.|||||.||.:|||.|..||:.|:.||:|::.:|
Human    98 LQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKEN 162

  Fly   375 LELKELCLYLDEERAHVAANALCAG--CG-----------AATRNALRDDGDGSS-SSTNADETI 425
            :||||||:.||||:     .|.|||  |.           |:|...:||.||||| |||.:.::.
Human   163 MELKELCVLLDEEK-----GAGCAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSP 222

  Fly   426 TALRNYAEQ-------------------------------------------------------R 435
            ...:::|..                                                       :
Human   223 DHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCK 287

  Fly   436 QLPQDLRHAHT------------------------------------------------------ 446
            ..|:..||.|.
Human   288 GSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLP 352

  Fly   447 -----------------------------------------------------------LNDQTL 452
                                                                       :|:.||
Human   353 RARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTL 417

  Fly   453 QYVRSLERRIQQLEEE-RTTPTAHLQQPTTPTPQATP-------------------------TPT 491
            .|||.||.|::||||| |..|.|...:...||..::.                         .||
Human   418 SYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCLPT 482

  Fly   492 VTSAATPAKSA----ASPHQQQQQQQQHQQQQQDIVAAAAAAAAAIQLPEPIAGRPEAVVRALQV 552
            :..:...:..|    :||:.               .|:.:..|...|.|||       ||.:|:|
Human   483 LPGSFRLSSGADGSNSSPNS---------------AASFSGHATPSQQPEP-------VVHSLKV 525

  Fly   553 LEVREQLERDRLGNLAGSALD-QMDDGEKALVREMCNVVWRKLEGSPHGPAA 603
            |:|:|.::|.:     |...: .:.:.|||:||||||||||||     |.||
Human   526 LDVQETIDRQQ-----GKEYEHDLSETEKAIVREMCNVVWRKL-----GDAA 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ccdc85	NP_608734.2	CCDC85	283..419	CDD:463009	80/149 (54%)
CCDC85A	NP_001335441.1	CCDC85	34..224	CDD:463009	91/225 (40%)
		PTZ00449	<224..>327	CDD:185628	5/102 (5%)