Protein Alignment okr and STH1

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_012140.1
• Gene: STH1 / 854680
• SGDID: S000001388
• Length: 1359
• Species: Saccharomyces cerevisiae
• Alignment Length: 858
• Identity: 239/858 - (27%)
• Similarity: 375/858 - (43%)
• Gaps: 193/858 - (22%)

  Fly    34 QQELEREQELDR---RRLGALRDASNTSELPLPI-------RFT-----ANSEYELAIAKVLARK 83
            |.|.:.::.::|   :||.||:  ||..|..|.:       |.|     .||..:.....|.|::
Yeast   361 QMEKDEQKRIERTAKQRLAALK--SNDEEAYLKLLDQTKDTRITQLLRQTNSFLDSLSEAVRAQQ 423

  Fly    84 FKVPMDNYVPDYGGKRVLGVRRCISRRPLHDPMACNALVLFHPPAYTEHERMGMDPTKVLVHVVV 148
                  |......|:.|         :|:                 |:.||...|..:| .|.:.
Yeast   424 ------NEAKILHGEEV---------QPI-----------------TDEEREKTDYYEV-AHRIK 455

  Fly   149 DP-------LLSNILRPHQREGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQG 206
            :.       |:...|:.:|..|:.:|   |.....:.|| |:|||||||||:|.::|:..|.
Yeast   456 EKIDKQPSILVGGTLKEYQLRGLEWM---VSLYNNHLNG-ILADEMGLGKTIQSISLITYLY--- 513

  Fly   207 PECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGT-P 270
             |.|..|...:|:.|.|.:.||..||.||...  |...:..|| .|...:|:.    ..|:|. .
Yeast   514 -EVKKDIGPFLVIVPLSTITNWTLEFEKWAPS--LNTIIYKGT-PNQRHSLQH----QIRVGNFD 570

  Fly   271 VLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDN-LTYQALMGLKTKRRVLLSGTPIQNDLT 334
            |||.:||.......:|.|::...:|.|||||:||:.: |::......:|:.|::|:|||:||:|.
Yeast   571 VLLTTYEYIIKDKSLLSKHDWAHMIIDEGHRMKNAQSKLSFTISHYYRTRNRLILTGTPLQNNLP 635

  Fly   335 EYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQ 399
            |.::|:|||.|::..:|..|:..|        ||.......|..:|.|:|...|    ||||.::
Yeast   636 ELWALLNFVLPKIFNSAKTFEDWF--------NTPFANTGTQEKLELTEEETLL----IIRRLHK 688

  Fly   400 IL------------TKYLPVKFEMVICAKLTAIQLELYTNFLKSDQV----------RRSLADCN 442
            :|            .|.||.|.|.||..||:.:|.:||...||.:.:          :..:...|
Yeast   689 VLRPFLLRRLKKEVEKDLPDKVEKVIKCKLSGLQQQLYQQMLKHNALFVGAGTEGATKGGIKGLN 753

  Fly   443 EKASLTALADITTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFM 507
            .|        |..|:|||:||.:           |:..:.|:..:....||...::|||.|||.:
Yeast   754 NK--------IMQLRKICNHPFV-----------FDEVEGVVNPSRGNSDLLFRVAGKFELLDRV 799

  Fly   508 LAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLF 572
            |...:|.|: :|::....||.:|:.|...|.:...::||||:...::|:::::.||.|:||.|.|
Yeast   800 LPKFKASGH-RVLMFFQMTQVMDIMEDFLRMKDLKYMRLDGSTKTEERTEMLNAFNAPDSDYFCF 863

  Fly   573 MLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQR 637
            :||::|||.||||..|:.:.:||.||||..|.||..|..|.|||....|.||:.:.|:||.||:|
Yeast   864 LLSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQKNEVRILRLITTDSVEEVILER 928

  Fly   638 QTHKKSLSSTII-----DNNESAEKH--FTR-------------------DDLKDLF--TFDANI 674
            ...|..:...:|     ||..:||:.  |.|                   |:|.|..  :.|..|
Yeast   929 AMQKLDIDGKVIQAGKFDNKSTAEEQEAFLRRLIESETNRDDDDKAELDDDELNDTLARSADEKI 993

  Fly   675 LSDTHDKLKCKR-----CVQNIQMKPP---------------------PEDTDCTSHLSQWYHCS 713
            |.|..||.:..:     ..|.:::.||                     .||::....:.|.....
Yeast   994 LFDKIDKERMNQERADAKAQGLRVPPPRLIQLDELPKVFREDIEEHFKKEDSEPLGRIRQKKRVY 1058

  Fly   714 NNRGLPDNILAQAWMDCK-CVSFVFHHRSQAQE----IVPSAEEEATDQPEEKPES------RKR 767
            .:.||.:....:|..|.. .:......|.:|:|    .....:|...:..|..||:      ...
Yeast  1059 YDDGLTEEQFLEAVEDDNMSLEDAIKKRREARERRRLRQNGTKENEIETLENTPEASETSLIENN 1123

  Fly   768 SSTPASDDSADED 780
            |.|.|.|:..:.|
Yeast  1124 SFTAAVDEETNAD 1136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	6/49 (12%)
		HepA	<156..650	CDD:440319	174/522 (33%)
		DEXHc_RAD54A	156..396	CDD:350825	82/241 (34%)
STH1	NP_012140.1	HSA	312..378	CDD:462194	3/16 (19%)
		PLN03142	370..>955	CDD:215601	204/666 (31%)
		SnAC	1006..1069	CDD:464219	8/62 (13%)
		COG5076	<1211..>1359	CDD:227408