Protein Alignment okr and ISW2

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_014948.1
• Gene: ISW2 / 854480
• SGDID: S000005831
• Length: 1120
• Species: Saccharomyces cerevisiae
• Alignment Length: 836
• Identity: 219/836 - (26%)
• Similarity: 370/836 - (44%)
• Gaps: 180/836 - (21%)

  Fly    27 KKNKRSCQQELEREQELDRRRLGALRDASNTSELPLPIRFTANSEYELAIAKVLARKFKVPMDNY 91
            |.|..|....:.:.:||..:.:..:.|.        |..:.|..:          :||.:.:|
Yeast    31 KSNGSSDDDNIGQSEELSDKEIYTVEDR--------PPEYWAQRK----------KKFVLDVD-- 75

  Fly    92 VPDYGG-----------KRVLGV----RRCISRRPLHD----------PMACNALVLFHP--PAY 129
             |.|..           |.:|||    |..|..:..||          ....|.|...|.  .:.
Yeast    76 -PKYAKQKDKSDTYKRFKYLLGVTDLFRHFIGIKAKHDKNIQKLLKQLDSDANKLSKSHSTVSSS 139

  Fly   130 TEHER---------MGMDPTKVLVHVVVDPLL---------SNILRPHQREGVRFMYECVEGKRG 176
            :.|.|         :..|..:.:|....:.:.         |..||.:|.:|:.::....|.|..
Yeast   140 SRHHRKTEKEEDAELMADEEEEIVDTYQEDIFVSESPSFVKSGKLRDYQVQGLNWLISLHENKLS 204

  Fly   177 NFNGCIMADEMGLGKTLQCVTLVWTL--LRQ--GPECKPTINKAIVVSPSSLVKNWEKEFTKW-- 235
            .    |:|||||||||||.::.:..|  ::|  ||        .:::.|.|.:.||.:||.||
Yeast   205 G----ILADEMGLGKTLQTISFLGYLRYVKQIEGP--------FLIIVPKSTLDNWRREFLKWTP 257

  Fly   236 ------LHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTPVLLISYETFRIYAEILCKYEVGMV 294
                  |||       :..|:.:.:|.:    :..||.  .||:.|||........|.:.....:
Yeast   258 NVNVLVLHG-------DKDTRADIVRNI----ILEARF--DVLITSYEMVIREKNALKRLAWQYI 309

  Fly   295 ICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFE 359
            :.||.||:||..:...|.:....:|.|:|::|||:||:|.|.::|:||:.|::.|.:.:|...||
Yeast   310 VIDEAHRIKNEQSALSQIIRLFYSKNRLLITGTPLQNNLHELWALLNFLLPDIFGDSELFDEWFE 374

  Fly   360 SAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLEL 424
                  ||  ::||:::..|   |:|..:::..::||....:.|.|..|.|..:...:|.:|::.
Yeast   375 ------QN--NSEQDQEIVI---QQLHSVLNPFLLRRVKADVEKSLLPKIETNVYVGMTDMQIQW 428

  Fly   425 YTNFLKS--DQVRRSLADCNEKASLTALADITTLKKICSHPDLIYEKLTAREKGFENSQNVLPSN 487
            |.:.|:.  |.|..::.....|..|  |..:..|:|.|:||.|           ||.::   |.
Yeast   429 YKSLLEKDIDAVNGAVGKREGKTRL--LNIVMQLRKCCNHPYL-----------FEGAE---PG- 476

  Fly   488 YKPKDLNPEL---SGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGT 549
             .|...:..|   |||.::||.:|..::.:|: :|::.|..::.||:.|.....|.:.:.|:||:
Yeast   477 -PPYTTDEHLIFNSGKMIILDKLLKRLKEKGS-RVLIFSQMSRLLDILEDYCYFRDFEYCRIDGS 539

  Fly   550 MSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDG 614
            .|.::|.:.:|.:|.|.|:.|:|:|:::|||.|:||:.|:.:.:||.||||..|.|||.|..|.|
Yeast   540 TSHEERIEAIDEYNKPNSEKFVFLLTTRAGGLGINLVTADTVILFDSDWNPQADLQAMDRAHRIG 604

  Fly   615 QKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIID---NNESAEKHFTRDDLKDLFTFDA-NIL 675
            |||..::||.|...:||||:::|...|..|...:|.   ..::|....::|||.|:..|.| |:.
Yeast   605 QKKQVHVYRFVTENAIEEKVIERAAQKLRLDQLVIQQGTGKKTASLGNSKDDLLDMIQFGAKNMF 669

  Fly   676 SDTHDKLKCKRCVQNIQMKPPPEDTDCTSHLSQWYHCSNNRGLPD--------NILAQAWMDCKC 732
            .....|:.....:.:|..|...:    |..|:..|   .:.||.|        |..|..|..
Yeast   670 EKKASKVTVDADIDDILKKGEQK----TQELNAKY---QSLGLDDLQKFNGIENQSAYEWNG--- 724

  Fly   733 VSFVFHHRSQAQEIVPSAEEEATDQPEE-----KPESRKRSSTPASDDSADEDFRG 783
                           .|.::::.|:..|     :.|.|:..:|.:.||...|...|
Yeast   725 ---------------KSFQKKSNDKVVEWINPSRRERRREQTTYSVDDYYKEIIGG 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	15/74 (20%)
		HepA	<156..650	CDD:440319	159/510 (31%)
		DEXHc_RAD54A	156..396	CDD:350825	75/251 (30%)
ISW2	NP_014948.1	PLN03142	1..1093	CDD:215601	219/836 (26%)