Protein Alignment okr and RAD16

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_009672.1
• Gene: RAD16 / 852411
• SGDID: S000000318
• Length: 790
• Species: Saccharomyces cerevisiae
• Alignment Length: 697
• Identity: 166/697 - (23%)
• Similarity: 282/697 - (40%)
• Gaps: 180/697 - (25%)

  Fly   109 RRPLHDPMACNALVLF--HP------------PAYTEHERMGMDPTKVLVHVVVDPLLSNILRPH 159
            :.|...|...|.|.|:  ||            |.|........|...:.            |.|.
Yeast   135 KSPKVTPYERNTLRLYEHHPELRNVFTDLKNAPPYVPQRSKQPDGMTIK------------LLPF 187

  Fly   160 QREGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSL 224
            |.||:.::   :..:...:.|.::|||||:|||:|.:.|:...|.:.|        ::||:|:..
Yeast   188 QLEGLHWL---ISQEESIYAGGVLADEMGMGKTIQTIALLMNDLTKSP--------SLVVAPTVA 241

  Fly   225 VKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTPVLLISY----ETFR----- 280
            :..|:.|..:...|:|......|.::...|:.|:         |..|:|.:|    ..||
Yeast   242 LMQWKNEIEQHTKGQLKIYIYHGASRTTDIKDLQ---------GYDVVLTTYAVLESVFRKQNYG 297

  Fly   281 ------IYAE--ILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYY 337
                  ::.:  :|...:...||.||.|.:|:..:.|.:|:..|||::|..|||||:||.:.|.|
Yeast   298 FRRKNGLFKQPSVLHNIDFYRVILDEAHNIKDRQSNTARAVNNLKTQKRWCLSGTPLQNRIGEMY 362

  Fly   338 SLVNF--VNPEMLGTAAVFKRNF----ESAILRGQNTDSTEQER--------------------Q 376
            ||:.|  :||        |.:.|    :.|....:.||....:.                    |
Yeast   363 SLIRFLNINP--------FTKYFCTKCDCASKDWKFTDRMHCDHCSHVIMQHTNFFNHFMLKNIQ 419

  Fly   377 R------AIEKTQELIGLVDQCIIRRT--NQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQ 433
            :      .:|....:..|:...::|||  .:.....||.:...|........:.:||.: |.:|.
Yeast   420 KFGVEGPGLESFNNIQTLLKNIMLRRTKVERADDLGLPPRIVTVRRDFFNEEEKDLYRS-LYTDS 483

  Fly   434 VRRSLADCNEKASLTALADITTL----KKICSHPDLIYEKLT------------------ARE-- 474
            .|:..:...|...|...|:|.||    :::..||||:.::|.                  |.|
Yeast   484 KRKYNSFVEEGVVLNNYANIFTLITRMRQLADHPDLVLKRLNNFPGDDIGVVICQLCNDEAEEPI 548

  Fly   475 -----------------KGFENSQNVLP---------------------SNYKPKDLNPEL--SG 499
                             :.|..:.|.|.                     .::|.:.:...|  ||
Yeast   549 ESKCHHKFCRLCIKEYVESFMENNNKLTCPVCHIGLSIDLSQPALEVDLDSFKKQSIVSRLNMSG 613

  Fly   500 KFM-------LLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSK 557
            |:.       |::.:......:...|.::.|.:|..|||.|...::..:..|:|.|:||..:|.:
Yeast   614 KWQSSTKIEALVEELYKLRSNKRTIKSIVFSQFTSMLDLVEWRLKRAGFQTVKLQGSMSPTQRDE 678

  Fly   558 VVDRF-NDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYI 621
            .:..| |:.:.:  :|::|.||||..|||..|:::|:.||.|||:.:.|:..||.|.||.:|..|
Yeast   679 TIKYFMNNIQCE--VFLVSLKAGGVALNLCEASQVFILDPWWNPSVEWQSGDRVHRIGQYRPVKI 741

  Fly   622 YRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEKHFTRDDLKDLF 668
            .|.....|||.:|::.|..|.::....|:.:|:|....|..||:.||
Yeast   742 TRFCIEDSIEARIIELQEKKANMIHATINQDEAAISRLTPADLQFLF 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	5/18 (28%)
		HepA	<156..650	CDD:440319	148/616 (24%)
		DEXHc_RAD54A	156..396	CDD:350825	69/288 (24%)
RAD16	NP_009672.1	HepA	<172..769	CDD:440319	149/639 (23%)
		RING-HC_RAD16-like	536..584	CDD:438229	5/47 (11%)