DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment okr and CHR34

DIOPT Version :9

Sequence 1:	NP_476661.1	Gene:	okr / 33507	FlyBaseID:	FBgn0002989	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_001325209.1	Gene:	CHR34 / 816684	AraportID:	AT2G21450	Length:	823	Species:	Arabidopsis thaliana

Alignment Length:	606	Identity:	156/606 - (25%)
Similarity:	274/606 - (45%)	Gaps:	123/606 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 KVLVHVVVDPLLSNILRPHQREGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQ 205
            |:.:|    |.....:||||.||.||:  |.........|||:|...|.|||...::.:.:.:..
plant   261 KMFIH----PWHDQEMRPHQTEGFRFL--CNNLAADEPGGCILAHAPGSGKTFLLISFLQSFMAM 319

  Fly   206 GPECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCL---PMEGGTKENTIRALEQFSMTSARL 267
            .|:.:|     :||.|..::::|::|||.|...::..|   .::..:::..::.|.|:....:
plant   320 DPQARP-----LVVLPKGIIESWKREFTLWEVEKIPLLDFYSVKAESRKQQLKVLGQWIKERS-- 377

  Fly   268 GTPVLLISYETFRIYAEILC--KYEVG-------------MVICDEGHRLKNSDNLTYQALMGLK 317
               :|.:.|:.|   ..|:|  .:|..             ::|.||||..:|.:.....:|..:|
plant   378 ---ILFLGYQQF---TRIICDDNFEAASEDCKLILLEKPTLLILDEGHTSRNKETYMLSSLARVK 436

  Fly   318 TKRRVLLSGTPIQNDLTEYYSLVNFVNPEML---GTAAVFKRNFESA-ILRGQNTDSTEQERQRA 378
            |:|:|:|:||..||::.|.:::::.|.|:.|   ||..:..|....| |.||:..:.:..    :
plant   437 TRRKVVLTGTLFQNNVEEVFNILDLVRPKFLKRPGTREIVSRIMSKAEIPRGKQVNQSSS----S 497

  Fly   379 IEKTQELIGLVDQCIIRRTN----------------QIL-------TKYLPVKFEMVICAKLTAI 420
            ||.|  ....|:..:.|.||                .||       :..||...|..:...|::|
plant   498 IEGT--FFAAVELTLQRSTNFSAKASLIKDLREMTRNILHYHKADFSGLLPGLSEFTVMLNLSSI 560

  Fly   421 QLELYTNFLKSDQVR--RSLADCNEKASLTALADITTLKKICSHPDL---IYEKLTAREKGF-EN 479
            |         .|:|:  |.: :..::.||.|...|        ||.|   :.|..:..|||| :|
plant   561 Q---------RDEVKGLRKM-ELFKQISLGAALYI--------HPKLKSFLEENPSNGEKGFSDN 607

  Fly   480 SQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGF- 543
            :..|:..:...|.:|.....|......:||...:.| :|:::.|.|...:...|:|....| |:
plant   608 NTTVMKLDKMLKKINVRDGVKMKFFLNLLALCESTG-EKLLVFSQYIVPIKTLERLMSSMK-GWR 670

  Fly   544 -----VRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPAND 603
                 ..:.|..|.::|...::|||: ..::.:|..|.||.|.|::|:||:|:.:.|...||:..
plant   671 LGKEMFTITGDSSNEQREWSMERFNN-SLEAKVFFGSIKACGEGISLVGASRVLILDVHLNPSVT 734

  Fly   604 EQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSS----------------TIIDNN 652
            :||:||.:|.|||:..|.|:|||:.|.||:..:..|.|:.:|.                ..||.:
plant   735 QQAVARAYRPGQKRKVYAYKLVAADSPEEENYETCTRKEMMSKMWFEWNVGSGREDFGFRAIDAD 799

  Fly   653 ESAEKHF----TRDDLKDLFT 669
            .|.:...    .::|:|.|:|
plant   800 HSGDAFLETTKMKEDIKCLYT 820

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	SNF2_N	159..466	CDD:278600	86/356 (24%)
		DEXDc	179..328	CDD:238005	40/166 (24%)
		HELICc	493..622	CDD:238034	40/134 (30%)
CHR34	NP_001325209.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0390
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	4	3.770