Protein Alignment okr and Chd6

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_775544.2
• Gene: Chd6 / 71389
• MGIID: 1918639
• Length: 2711
• Species: Mus musculus
• Alignment Length: 667
• Identity: 182/667 - (27%)
• Similarity: 296/667 - (44%)
• Gaps: 100/667 - (14%)

  Fly   153 SNILRPHQREGVRFM----YECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTI 213
            ||.||.:|.||:.::    |        |...||:|||||||||:|.:..:..:..:|..
Mouse   457 SNRLREYQLEGMNWLLFNWY--------NRKNCILADEMGLGKTIQSIAFLSEIFVRGIH----- 508

  Fly   214 NKAIVVSPSSLVKNWEKEFTKW-------LHGRLLCLPMEGGTKENTIRALEQFSMT--SARLGT 269
            ...::::|.|.:.|||:||..|       .||..:...|           ::|:.|.  .|: |.
Mouse   509 GPFLIIAPLSTITNWEREFRTWTEMNAIVYHGSQISRQM-----------IQQYEMVYRDAQ-GN 561

  Fly   270 P--------VLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSG 326
            |        |::.::|........|.|.....||.||.|||||.:....:.|..:..:.:|||:|
Mouse   562 PLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTG 626

  Fly   327 TPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQ 391
            ||:||.:.|.:||:||:.|....:...|...|...        .||       |:.::|..::..
Mouse   627 TPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDL--------KTE-------EQVKKLQSILKP 676

  Fly   392 CIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTL 456
            .::||....:.|.|..|.|.:|..:||.||.:.|...|:.: ........|:......:..:..|
Mouse   677 MMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKN-FSFLTKGANQHNMPNLINTMMEL 740

  Fly   457 KKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNP--ELSGKFMLLDFMLAAIRAEGNDKV 519
            :|.|:||.||.   .|.||..|:.:....|......|..  :.:||.:|:|.:|..:.| |..||
Mouse   741 RKCCNHPYLIN---GAEEKILEDFRKAHSSEASDFQLQAMIQAAGKLVLIDKLLPKLIA-GGHKV 801

  Fly   520 VLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLN 584
            ::.|...:.||:.|....:|:|.:.|:||.:....|...:|||..|:||.|:|:|.::|||.|:|
Mouse   802 LIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGIN 866

  Fly   585 LIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTII 649
            |..|:...:||.||||.||.||.||..|.||.|...:|||:...|.|.::..:.:.|..|...|:
Mouse   867 LTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAIL 931

  Fly   650 DN-----NESAEKHFTRDDLKDLFTFDA-NILSDTHDKLK--CKRCVQNIQMKPP-----PEDTD 701
            .:     :.:..:..::.:::||....| ..|.|..|:..  |:..:..|..:..     ..:..
Mouse   932 QDINRKGSTNGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGK 996

  Fly   702 CTSHLSQWYHCSNNR---GLPDNILAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEEKPE 763
            .::.....:..|.||   .|.|....|.|             ::..|:...|..|......::|.
Mouse   997 GSTFAKASFVASGNRTDISLDDPNFWQKW-------------AKIAELDTEANNEKESLVIDRPR 1048

  Fly   764 SRKRSSTPASDDSADED 780
            .||::.   ..:|.:||
Mouse  1049 VRKQTK---HYNSFEED 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	156/516 (30%)
		DEXHc_RAD54A	156..396	CDD:350825	70/260 (27%)
Chd6	NP_775544.2	Required for DNA-dependent ATPase activity. /evidence=ECO:0000250	1..746		89/329 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..52
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..243
		PTZ00449	<101..372	CDD:185628
		CD1_tandem_CHD5-9_like	287..352	CDD:349315
		CD2_tandem_CHD5-9_like	371..429	CDD:349310
		PLN03142	459..>984	CDD:215601	164/569 (29%)
		DEAD-like_helicase_N	460..681	CDD:475120	70/260 (27%)
		DEAH box	597..600		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1318..1389
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1951..1978
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1997..2059
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2124..2147
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2321..2350
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2373..2419
		BRK	2402..2435	CDD:470653
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2550..2602
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2641..2711