Protein Alignment okr and EP400

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_056224.3
• Gene: EP400 / 57634
• HGNCID: 11958
• Length: 3123
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 84/325 - (25%)
• Similarity: 145/325 - (44%)
• Gaps: 45/325 - (13%)

  Fly   151 LLSNILRPHQREGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLV---------WTLLRQG 206
            ||...||.:|:.|:.::.:..   |.|.|| |:|||.|||||:|.:...         |     |
Human  1050 LLYGALRDYQKIGLDWLAKLY---RKNLNG-ILADEAGLGKTVQIIAFFAHLACNEGNW-----G 1105

  Fly   207 PECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTPV 271
            |.        :||..|..:..||.|..:|..| |..|...|..:|...:..|.....|..    |
Human  1106 PH--------LVVVRSCNILKWELELKRWCPG-LKILSYIGSHRELKAKRQEWAEPNSFH----V 1157

  Fly   272 LLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEY 336
            .:.||..|........:.....::.||..|:|......::|:..|::::|:||..:|:.|...|.
Human  1158 CITSYTQFFRGLTAFTRVRWKCLVIDEMQRVKGMTERHWEAVFTLQSQQRLLLIDSPLHNTFLEL 1222

  Fly   337 YSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQIL 401
            :::|:|:.|.:       .|.:.|:.||..:.:|.:...:..|    .|..:....|:|||.:.:
Human  1223 WTMVHFLVPGI-------SRPYLSSPLRAPSEESQDYYHKVVI----RLHRVTQPFILRRTKRDV 1276

  Fly   402 TKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTLKKICSHPDLI 466
            .|.|..|:|.|:..:|:..|..||.:.:.....:.:|...:   .:..|:.:..|::||:||.|:
Human  1277 EKQLTKKYEHVLKCRLSNRQKALYEDVILQPGTQEALKSGH---FVNVLSILVRLQRICNHPGLV 1338

  Fly   467  466
            Human  1339  1338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	82/320 (26%)
		DEXHc_RAD54A	156..396	CDD:350825	62/248 (25%)
EP400	NP_056224.3	EP400_N	1..469	CDD:434938
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..65
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	125..154
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..261
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	282..359
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	509..558
		PAT1	518..>780	CDD:401645
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	597..622
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	648..734
		HSA	764..835	CDD:214727
		HepA	849..>1338	CDD:440319	83/323 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	879..931
		Interactions with RUVBL1 and RUVBL2	915..1329		78/314 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	961..988
		DEAD-like_helicase_N	1055..1271	CDD:475120	62/248 (25%)
		DEAH box-like	1183..1186		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1431..1546
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1751..1771
		SF2_C_SNF	1861..1986	CDD:350180
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2083..2108
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2251..2275
		Interaction with ZNF42. /evidence=ECO:0000250	2488..2753
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2488..2566
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2629..2652
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2785..2833
		SP1-4_N	<2840..3065	CDD:425404
		PRK12323	<3004..>3123	CDD:481241
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	3079..3123