Protein Alignment okr and ercc6

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001361595.1
• Gene: ercc6 / 548810
• XenbaseID: XB-GENE-1007918
• Length: 1371
• Species: Xenopus tropicalis
• Alignment Length: 675
• Identity: 196/675 - (29%)
• Similarity: 330/675 - (48%)
• Gaps: 84/675 - (12%)

  Fly   156 LRPHQREGVRFMYE--CVEGKRGNFNGCIMADEMGLGKTLQCVT----LVWTLLR-QGPECK-PT 212
            |..:|:.|||:::|  |.:.      |.|:.||||||||:|.:.    |.::.:| :|.:.: ..
 Frog   467 LYKYQQTGVRWLWELHCQQA------GGILGDEMGLGKTIQIIAFLAGLSYSRIRTRGSDYRYEG 525

  Fly   213 INKAIVVSPSSLVKNWEKEF-TKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTPVLLISY 276
            :..:|:|.|::::..|.||| |.|...|::.|...|......::.:.:...     |..:|:.||
 Frog   526 LGPSIIVCPATVMHQWVKEFHTWWPQFRVVILHETGSYAGKKVKLIGELGN-----GCGILITSY 585

  Fly   277 ETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVN 341
            ...|:..|.|.||....:|.||||:::|.:.....|....:|..|::|||:|:||:|.|.:||.:
 Frog   586 SYVRLMQEELQKYHWHYIILDEGHKIRNPNAGVTLACKQFRTPHRIILSGSPMQNNLRELWSLFD 650

  Fly   342 FVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRR--TNQILTKY 404
            ||.|..|||..||...|...|..|..::::..:.:.|.:....|...::..::||  .:..::..
 Frog   651 FVFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKADVKMSLA 715

  Fly   405 LPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTLKKICSHPDLIYEK 469
            ||.|.|.|:..:||..|.::|..|:.|.:|...|     ...:.....:..|:|||:||||
 Frog   716 LPDKNEQVLFCRLTDEQRQVYQTFIDSKEVYGIL-----NGEMQVFPGLIALRKICNHPDL---- 771

  Fly   470 LTAREKGFENSQNVLPSNYKPKDLNPE-------LSGKFMLLDFMLAAIRAEGNDKVVLISNYTQ 527
                   |.....:|... :.:||..|       .|||.::::.:|.....:|: :|:|.:...|
 Frog   772 -------FSGGPKILKGT-RDEDLEEEEQFGFWKRSGKLIVVEALLKIWHRQGH-RVLLFTQSRQ 827

  Fly   528 TLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLF 592
            .|.:.|...|.|.|.::::|||.:|..|..::.::|:..| .|:|:|:::.||.|:||.||||:.
 Frog   828 MLQILEVFVRSRCYSYLKMDGTTTIASRQPLIAKYNEDPS-LFVFLLTTRVGGLGVNLTGANRVI 891

  Fly   593 MFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEK 657
            ::||||||:.|.||..|.||.||||...:|||:.:|:|||||..||..|:.|::.:: .:....:
 Frog   892 IYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQIFKQFLTNRVL-KDPKQRR 955

  Fly   658 HFTRDDLKDLFTFDANILSDTHDKLKCKRCV----QNIQMKPPPED-----TDCTSHLSQWYHCS 713
            .|..:||.:||||.:   .||....:.....    .::|:...|.:     |..|.|.......|
 Frog   956 FFKSNDLYELFTFSS---PDTSHGTETSAIFAGTGSDVQVVKRPGNQNVAHTQTTFHKEPPVSIS 1017

  Fly   714 NNRGLP----DNILAQAWMDCKCVSFVFHHRSQAQEIVPSA-----------EEEATDQPE---- 759
            |...||    :::|..|..:...|.|.....|   |:.||.           :...|:.||
 Frog  1018 NTPSLPSKPLNSVLQHAQENPMLVGFEARSNS---EVTPSTSIKLESGKDCKQGSLTEAPENCHR 1079

  Fly   760 -EKPESRKRSSTPASDDSADEDFRG 783
             .|.:::.:|...:.....|..:.|
 Frog  1080 KHKAKTKHQSKGKSVKRRKDAKYEG 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	163/511 (32%)
		DEXHc_RAD54A	156..396	CDD:350825	74/248 (30%)
ercc6	NP_001361595.1	COG4913	<24..>206	CDD:443941
		cc_ERCC-6_N	61..137	CDD:411064
		HepA	<458..948	CDD:440319	163/510 (32%)
		CSB_WHD	1300..1371	CDD:439329