DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment okr and CG10445

DIOPT Version :9

Sequence 1:	NP_476661.1	Gene:	okr / 33507	FlyBaseID:	FBgn0002989	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_001246974.1	Gene:	CG10445 / 40938	FlyBaseID:	FBgn0037531	Length:	945	Species:	Drosophila melanogaster

Alignment Length:	804	Identity:	158/804 - (19%)
Similarity:	261/804 - (32%)	Gaps:	327/804 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 SRRPLHDPMACNALVLFHP-PAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQREGVRFMYECV 171
            |.:.|::|:        .| ||..:.|:   .|..:||.          |..||:..:::|.
  Fly   181 SLKTLYEPI--------QPRPAIDDLEK---QPALLLVR----------LLKHQQSCLKWMQ--- 221

  Fly   172 EGKRGNFNGCIMADEMGLGKTL---------------------QCVTLVWT-------------- 201
            ..:|...:|.|:||:|||||||                     :.:||.||
  Fly   222 FRERQKISGGILADDMGLGKTLSMIALILASEETKNRKREEKKKALTLKWTQEFNRVYCKEIRKI 286

  Fly   202 --------------------------------------------------------LLRQGPECK 210
                                                                    ||.:.||.:
  Fly   287 SMFDDEEESGKEEEQYEPPEKRTCHVKTKKINQFRILDDDDNDAGDKAVVEDEQKDLLAKTPEPE 351

  Fly   211 ----------------PTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRALEQ 259
                            |:.| .:||.|.|::..|..|             :.....:|.||.|..
  Fly   352 VFSSDEEEEHLSNGRYPSAN-TLVVCPMSVMCQWAHE-------------VASKVAQNAIRVLTF 402

  Fly   260 FSMTSARLGTPVLLISYETFRIYAEILCKYEV-------------------GMVICDEGHRLKNS 305
            .......:|       .|.||.|..::..|.:                   ..||.||.|.::||
  Fly   403 HGPNRHEIG-------IEAFRSYDLVITSYNLVVNELKRYGNTSPLFAVYWNRVILDEAHIIRNS 460

  Fly   306 DNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDS 370
            ......::..|:......|:|||:||...:.::|:.|||.........:|:|...::| |.
  Fly   461 KTNCCNSVCQLRAHCHWALTGTPVQNRGVDVFALLRFVNVPNFQDLQQWKKNLNESML-GH---- 520

  Fly   371 TEQERQRAIEKTQELIGLVDQCIIRRTNQIL-----TKYLP-----------VKFEMVICAKLTA 419
                        :.|..::...::|||.|.|     ...||           .|.||.:...|:|
  Fly   521 ------------RRLNFIIKPLMLRRTKQKLQASGDMPALPSLKIELICVQLSKTEMAVYQILSA 573

  Fly   420 IQLELYTNFLKSDQVRRSLADCN------------------------------------EK-ASL 447
            |..:::|.||.  |..:..:|.|                                    || ..:
  Fly   574 ISKKIFTQFLL--QREKGNSDLNYYSLERTPQFIAGHMSDERYNEIYERFLKSLGYNPGEKILGI 636

  Fly   448 TALADITTLKKICSHPDLIY--------------------------------------------- 467
            ..|..:..|::.|.||.|:.
  Fly   637 YILVLLLRLRQFCCHPGLMIGMLRGALTAEDVQNVKVDASDVEGQLKMDVLAELDKFDETDSEDD 701

  Fly   468 ----EKLTAREKGFE--------NSQNV-------LPSNYKPKD----------LNPE------- 496
                |..|.|:..|:        ..:||       ||:....:|          |||:
  Fly   702 CCDEEDSTRRDGNFKLEVIKDEIKEENVPWDSGDDLPTASSFEDQLDSARALKLLNPQNPIFQFI 766

  Fly   497 -LSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVD 560
             .|.|..::...|..:....|||:::.|.:...|.:..:..:...:..:..:|.::.|:|..|:.
  Fly   767 RPSAKLKMVIDKLEELLTGTNDKIIVTSQWVSYLAIVRKRLQDLSWETLDFNGQLTAKEREIVLR 831

  Fly   561 RFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLV 625
            .|| ..::..:.:||..|||.||||..||.:.:.|..|||..:.||..|::|.||.||.:|||.:
  Fly   832 DFN-ANNEKRVLLLSLTAGGVGLNLNVANHMLIVDLHWNPQLERQAQDRIYRYGQTKPTFIYRYM 895

  Fly   626 ASGSIEEKILQRQTHKKSLSSTII 649
            ...::|::|...|..|..::..::
  Fly   896 CQDTVEQRIKSLQDCKLEIAKVVL 919

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	SNF2_N	159..466	CDD:278600	90/485 (19%)
		DEXDc	179..328	CDD:238005	47/274 (17%)
		HELICc	493..622	CDD:238034	40/136 (29%)
CG10445	NP_001246974.1	HepA	<90..945	CDD:223627	158/804 (20%)
CG10445	NP_001246974.1	DEAD-like_helicase_N	209..534	CDD:421690	65/365 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467139
Domainoid	1	1.000	47	1.000	Domainoid score	I705
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840