DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment okr and rad54l

DIOPT Version :9

Sequence 1:	NP_476661.1	Gene:	okr / 33507	FlyBaseID:	FBgn0002989	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_001001241.1	Gene:	rad54l / 407922	XenbaseID:	XB-GENE-979988	Length:	742	Species:	Xenopus tropicalis

Alignment Length:	759	Identity:	415/759 - (54%)
Similarity:	543/759 - (71%)	Gaps:	35/759 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MRRSLAPSQRGPLRPESRHSFTPPLLKKNKRSCQQELE--REQELDRRRLGALRDASNT--SELP 61
            |||||||||               |.|:.:.|..::.|  .:....|:||.:.:|....  |...
Frog     1 MRRSLAPSQ---------------LAKRKQGSSSEDEEWCEDAVPKRKRLSSNKDIRENWISPFR 50

  Fly    62 LPIRFTAN-------SEYELAIAKVLARKFKVPMDNYVPDYGGKRVLGVRRCISRRPLHDPMACN 119
            .|:....|       .::|..|..:|::.||:|:.||.... |.|.||:::...||.||||....
Frog    51 KPLAQVTNRPTCLDSKQHEAFIRSILSKPFKIPIPNYQGGL-GLRALGIKKAGIRRALHDPFEEG 114

  Fly   120 ALVLFHPPAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQREGVRFMYECVEGKR-GNFNGCIM 183
            ||||:.||..:.|:.:.:|..||.|||||||:|..:|||||||||:|::|||.|:| ...:|.||
Frog   115 ALVLYEPPQLSAHDLLKVDKEKVPVHVVVDPVLGKVLRPHQREGVKFLWECVTGRRISGSHGSIM 179

  Fly   184 ADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGG 248
            ||||||||||||:||:||||||.|:.||.|.||:||.||||||||..|.:|||.||:..|.::||
Frog   180 ADEMGLGKTLQCITLIWTLLRQSPDAKPEIEKAVVVCPSSLVKNWYNEVSKWLGGRIQPLAIDGG 244

  Fly   249 TKENTIRALEQF-SMTSARLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQA 312
            :||...:.|..| :....|:.:.:|:|||||||::||:|.:..||:||||||||||||:|.||||
Frog   245 SKEEIDKKLSGFMNQHGMRVPSAILIISYETFRLHAEVLHRGSVGLVICDEGHRLKNSENQTYQA 309

  Fly   313 LMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQR 377
            |..|.|.||||:|||||||||.||:|||:|||..:||||..||:.||..||:|::.|::..:||:
Frog   310 LNSLNTVRRVLISGTPIQNDLLEYFSLVHFVNAGILGTAQEFKKRFEIPILKGRDADASAADRQK 374

  Fly   378 AIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCN 442
            ..||.:||||:|::|:||||:.||:||||||.|.|:|.:||.:|.|||..|||.   .:...|.|
Frog   375 GEEKLKELIGVVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQSELYKLFLKQ---AKPAEDLN 436

  Fly   443 E-KASLTALADITTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDF 506
            | |.|:::|:.||:|||:|:||.|||||....|:||:.:.|:.||.|..|.:.|:||||.::||:
Frog   437 EGKISVSSLSSITSLKKLCNHPSLIYEKCVEEEEGFQGALNLFPSGYSTKSVEPQLSGKMLVLDY 501

  Fly   507 MLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFL 571
            :||..|:..:|||||:|||||||||||:|.|.|:|.:||||||||||||:|:|:|||.|.|..|:
Frog   502 ILAVTRSTSSDKVVLVSNYTQTLDLFEKLCRTRRYLYVRLDGTMSIKKRAKIVERFNSPSSPEFI 566

  Fly   572 FMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQ 636
            ||||||||||||||||||||.|||||||||||||||||||||||||.|:||||:::|:|||||.|
Frog   567 FMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCFIYRLLSTGTIEEKIFQ 631

  Fly   637 RQTHKKSLSSTIIDNNESAEKHFTRDDLKDLFTFDANILSDTHDKLKCKRCVQNIQMKPPPEDTD 701
            ||||||:|||.::|..:..|:||:..:||:||..:.|..||||||.||:|||...|::|||:.||
Frog   632 RQTHKKALSSCVVDEEQDVERHFSIGELKELFILNENTTSDTHDKFKCRRCVNGHQVRPPPDGTD 696

  Fly   702 CTSHLSQWYHCSNNRGLPDNILAQAWMDCKCVSFVFHHRSQAQE 745
            |||.||||.||::.|||.|.:|..|| |. .::|.|||:|..::
Frog   697 CTSDLSQWNHCADKRGLQDPVLVSAW-DA-AITFTFHHQSHEEQ 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	SNF2_N	159..466	CDD:278600	179/309 (58%)
		DEXDc	179..328	CDD:238005	92/149 (62%)
		HELICc	493..622	CDD:238034	96/128 (75%)
rad54l	NP_001001241.1	Rad54_N	12..>136	CDD:370043	36/124 (29%)
		HepA	<147..666	CDD:223627	320/521 (61%)
		DEXHc_RAD54A	151..393	CDD:350825	145/241 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	334	1.000	Domainoid score	I1141
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H48227
Inparanoid	1	1.050	785	1.000	Inparanoid score	I511
OMA	1	1.010	-	-		QHG58624
OrthoDB	1	1.010	-	-		D93727at2759
OrthoFinder	1	1.000	-	-		FOG0001533
OrthoInspector	1	1.000	-	-		oto103282
Panther	1	1.100	-	-	LDO	PTHR45629
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3107
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080