Protein Alignment okr and Chd7

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001264078.1
• Gene: Chd7 / 320790
• MGIID: 2444748
• Length: 2986
• Species: Mus musculus
• Alignment Length: 575
• Identity: 168/575 - (29%)
• Similarity: 282/575 - (49%)
• Gaps: 88/575 - (15%)

  Fly   153 SNILRPHQREGVRFM----YECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTI 213
            :|.||.:|.|||.::    |        |...||:|||||||||:|.:|.::.:..:|..
Mouse   955 NNKLREYQLEGVNWLLFNWY--------NMRNCILADEMGLGKTIQSITFLYEIYLKGIH----- 1006

  Fly   214 NKAIVVSPSSLVKNWEKEFTKW-------LHGRLLCLPMEGGTKENTIRALEQ-FSMTSARLGTP 270
            ...:|::|.|.:.|||:||..|       .||        ......||:..|. |.....|
Mouse  1007 GPFLVIAPLSTIPNWEREFRTWTELNVVVYHG--------SQASRRTIQLYEMYFKDPQGR---- 1059

  Fly   271 VLLISYETFRIYAEILCKYEVGM-------------VICDEGHRLKNSDNLTYQALMGLKTKRRV 322
            |:..||:    :..|:..:|:.:             |:.||.|||||.:....:.|..:..:.:|
Mouse  1060 VIKGSYK----FHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKV 1120

  Fly   323 LLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIG 387
            ||:|||:||.:.|.:||::|:.|....:...|.:.|...        .||       |:.|:|..
Mouse  1121 LLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDL--------KTE-------EQVQKLQA 1170

  Fly   388 LVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALAD 452
            ::...::||..:.:.|.|..|.|.:|..:||.||.:.|...|:.:..  .|:....:|::..|.:
Mouse  1171 ILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFT--FLSKGGGQANVPNLLN 1233

  Fly   453 -ITTLKKICSHPDLI---YEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRA 513
             :..|:|.|:||.||   .||:.   :.|:.:.|....:::.:.: .:.:||.:|:|.:|..::|
Mouse  1234 TMMELRKCCNHPYLINGAEEKIL---EEFKETHNAESPDFQLQAM-IQAAGKLVLIDKLLPKLKA 1294

  Fly   514 EGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKA 578
             |..:|::.|...:.||:.|....:|:|.:.|:||.:....|...:|||:.|:||.|:|:|.::|
Mouse  1295 -GGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRA 1358

  Fly   579 GGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKS 643
            ||.|:||..|:...:||.||||.||.||.||..|.||.|...||||:...|.|.::..:.:.|..
Mouse  1359 GGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLG 1423

  Fly   644 LSSTII------DNNESAEKHFTRDDLKDLFTFDA-NILSDTHDKLKCKRCVQNI 691
            |...::      :|..:..:..::.:::||....| ..|.|..|: ..|.|.::|
Mouse  1424 LDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDE-GSKFCEEDI 1477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	157/528 (30%)
		DEXHc_RAD54A	156..396	CDD:350825	72/264 (27%)
Chd7	NP_001264078.1	Glutenin_hmw	<23..553	CDD:367362
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..146
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	159..180
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..246
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..307
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	372..412
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	461..792
		CD1_tandem_CHD5-9_like	786..850	CDD:349315
		CD2_tandem_CHD5-9_like	869..926	CDD:349310
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	928..949
		PLN03142	957..>1556	CDD:215601	167/573 (29%)
		DEAH box	1095..1098		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1566..1590
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1826..1851
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2151..2274
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2366..2393
		BRK	2552..2593	CDD:462196
		BRK	2631..2675	CDD:197800
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2812..2861
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2924..2986