Protein Alignment okr and Chd3

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_038943541.1
• Gene: Chd3 / 303241
• RGDID: 1311923
• Length: 2120
• Species: Rattus norvegicus
• Alignment Length: 759
• Identity: 200/759 - (26%)
• Similarity: 328/759 - (43%)
• Gaps: 162/759 - (21%)

  Fly   127 PAYTEHER---------MGMDPTKVLVH---------------VVVDPLLSNILRP--------- 158
            |.|.:|::         ||.||.:...:               ...||.:....:|
  Rat   732 PEYDDHKQSYWRHRELIMGEDPAQPRKYKKKKKEIQGDGPPSSPTNDPTVKYETQPRFITATGGT 796

  Fly   159 ---HQREGVRFM-YECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVV 219
               :|.||:.:: :...:|     ...|:|||||||||:|.:..:::|.::|    .|....:|.
  Rat   797 LHMYQLEGLNWLRFSWAQG-----TDTILADEMGLGKTIQTIVFLYSLYKEG----HTKGPFLVS 852

  Fly   220 SPSSLVKNWEKEFTKWL------------HGRLLCLPMEGGTKENTIR-ALEQFSM-TSARLGTP 270
            :|.|.:.|||:||..|.            ..|.:....|...::|.|: ..:.|.| ..|::...
  Rat   853 APLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFH 917

  Fly   271 VLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTE 335
            |||.|||...|....|.......::.||.|||||:.:..::.|.|.|...::||:|||:||:|.|
  Rat   918 VLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEE 982

  Fly   336 YYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQI 400
            .:.|:||:.||.......|...|         .|.:::::   |:|..:|:|   ..::||....
  Rat   983 LFHLLNFLTPERFNNLEGFLEEF---------ADISKEDQ---IKKLHDLLG---PHMLRRLKAD 1032

  Fly   401 LTKYLPVKFEMVICAKLTAIQLELYTNFL-KSDQVRRSLADCNEKASLTALADITTLKKICSHPD 464
            :.|.:|.|.|:::..:|:.:|.:.|...| ::.:...|....|:.:.|..:.|   |||.|:||.
  Rat  1033 VFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMD---LKKCCNHPY 1094

  Fly   465 LIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTL 529
            |.  .:.|.|      ...|||.........:.|||.:||..||..::.:|: :|::.|..|:.|
  Rat  1095 LF--PVAAME------SPKLPSGAYEGGALIKSSGKLLLLQKMLRKLKEQGH-RVLIFSQMTKML 1150

  Fly   530 DLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMF 594
            ||.|.......|.:.|:||.::...|.:.:||||.|.:..|.|:||::|||.|:||..|:.:.:|
  Rat  1151 DLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIF 1215

  Fly   595 DPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTII-DNNESAEKH 658
            |.||||.||.||.:|..|.||.....|||.|...|:||:|.|....|..|:..:: ....|....
  Rat  1216 DSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKAGS 1280

  Fly   659 FTRDDLKDLFTF-----------------DANILSDTHDKLKCKRCVQNIQMKPPPEDTD---CT 703
            .::.:|.|:..|                 |::::.  :|.....|.:...|  ...:|||   ..
  Rat  1281 MSKQELDDILKFGTEELFKDENEGENKEEDSSVIH--YDNEAIARLLDRNQ--DATDDTDVQNMN 1341

  Fly   704 SHLSQW----YHCSNNRGL----------PDNILAQAWMDCKCVSFVFHHRSQAQEIV------- 747
            .:||.:    |.......:          .:|:....|     ...:.||..|.||.:
  Rat  1342 EYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYW-----EKLLRHHYEQQQEDLARNLGKG 1401

  Fly   748 ----------PSAEEEATDQPE-------------EKPESRKRS 768
                      .:|:|:..:|.|             |:||.|::|
  Rat  1402 KRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQS 1445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	161/522 (31%)
		DEXHc_RAD54A	156..396	CDD:350825	74/266 (28%)
Chd3	XP_038943541.1	CHDNT	203..256	CDD:462357
		TNG2	<384..488	CDD:227367
		PHD1_CHD_II	443..485	CDD:277006
		PHD2_CHD_II	519..561	CDD:277007
		CD1_tandem_CHD3-4_like	566..644	CDD:349314
		CD2_tandem_CHD3-4_like	689..743	CDD:349309	3/10 (30%)
		PLN03142	780..>1334	CDD:215601	169/593 (28%)
		DEXHc_CHD3	797..1028	CDD:350813	73/254 (29%)
		DUF1087	<1375..1418	CDD:461922	8/47 (17%)
		CHDII_SANT-like	1439..1578	CDD:461920	4/7 (57%)
		PHA03169	<1570..>1761	CDD:223003
		CHDCT2	1800..1926	CDD:462358