Protein Alignment okr and rdh54

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_593038.2
• Gene: rdh54 / 2541798
• PomBaseID: SPAC22F3.03C
• Length: 811
• Species: Schizosaccharomyces pombe
• Alignment Length: 756
• Identity: 252/756 - (33%)
• Similarity: 374/756 - (49%)
• Gaps: 119/756 - (15%)

  Fly    17 SRHSFTPPLLKKNK--RSCQQELEREQELDRRRLGA---LRDASNTSELPLPIRFTANSEYELAI 76
            |.||..|. :|:.:  |...:|:..|:|:......|   :.|:.....:|
pombe    96 SCHSRVPQ-IKEGELLRISGKEISIEKEISAESYEAGTHIDDSLRDVHMP--------------- 144

  Fly    77 AKVLARKFKVPMDNYVPDYGGKRVLGVRRCISR--RPLHDPMACNALVLFHPPAYTEHERMGMDP 139
              .:.||||.|:          |...:.:.||.  :|.|||....|||:..|..:        ||
pombe   145 --EMKRKFKPPL----------RPNTMYQTISALPKPRHDPTVLGALVMSRPKTW--------DP 189

  Fly   140 TKVLVHVVVDPLLSNILRPHQREGVRFMYECVEGKRGNFN-GCIMADEMGLGKTLQCVTLVWTLL 203
             :..|.||:||.||..|..||||||.|:|:|:.|..|... ..|:|||||||||||.:|:|||||
pombe   190 -RTHVDVVIDPFLSKHLYSHQREGVSFLYDCLLGMEGKCGYSAILADEMGLGKTLQTITVVWTLL 253

  Fly   204 RQG--PECKPTINKAIVVSPSSLVKNWEKEFTKWL-HGRLLCLPMEGGTKENTIRALEQFSMTSA 265
            :|.  .....|||.|:||:|.:|:||||.||..|| |.|:         .....|..|.|...::
pombe   254 KQSYYANRSSTINNAMVVAPVTLLKNWENEFYNWLGHERI---------HVYIARCAEDFQEFTS 309

  Fly   266 RLGTPVLLISYETFRIYAEIL-CKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPI 329
            .....:::..|||...|.... |..::.::||||.||||:..:.|:..|..|||::|:||:|||:
pombe   310 NKTYSIIITGYETVCTYLRNYGCGIDIDLLICDEAHRLKSMSSQTWITLNKLKTRKRLLLTGTPL 374

  Fly   330 QNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCII 394
            ||||:||:|:|||:.|..|||...||..:|..|||.::.:::.::......:.|.|........:
pombe   375 QNDLSEYFSMVNFIIPGSLGTPNSFKAQYERPILRSRSMNASSRDISLGAARLQRLFEFTSNFTL 439

  Fly   395 RRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTLKKI 459
            ||...||.|:||.:.::|:..|.|..|..:|.:.|  |..:.|:   ::|...  |..:|.|.||
pombe   440 RRKANILAKHLPPRTDIVLFIKPTHQQENVYGHVL--DGFKSSV---DQKGYY--LKILTRLSKI 497

  Fly   460 CSHPDLI------YEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDK 518
            |:...|:      :.....::|.....:|:|.|           |.|..:|..:|.:.: .|..|
pombe   498 CNSTILLRNEKENFLSTELQDKHVFEQENMLLS-----------SSKLQILAALLKSFQ-RGCQK 550

  Fly   519 VVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSF-LFMLSSKAGGCG 582
            .|::|.|.:||:|.|.........|.:|.|:....:|..:|..||......| :.:|||||||||
pombe   551 AVIVSQYKETLELIELFLSILHVRFCKLLGSTPFSERDLIVHNFNTSSFKEFSVLLLSSKAGGCG 615

  Fly   583 LNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSST 647
            |||.|:.||.:::|.||||.|.||::|::|.|||:|..||..::||.::|:|..||..|:.|||:
pombe   616 LNLTGSTRLIIYEPSWNPAQDLQALSRIYRSGQKRPVCIYTFLSSGMLDERIFIRQNTKQGLSSS 680

  Fly   648 IIDNNESAEKH-FTRDDLKDLF---------TFDANILSDTHDKLKCKRCVQNIQMKPP------ 696
            .||::.|.:|: ||.:|:|.||         |::....||..|.|..|        |.|
pombe   681 FIDSDASQKKNFFTGEDIKTLFSYSKTETCLTYELAFDSDEIDSLTKK--------KDPLTKIDH 737

  Fly   697 ----PEDTDCTSHLSQWYHCS----NNRG--LPDNILAQAW 727
                |...:....:|.|...|    .|.|  .|:|.. |.|
pombe   738 TIDSPNTKEKDKEISSWKKASEYMDTNLGKKCPENAF-QGW 777

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	15/51 (29%)
		HepA	<156..650	CDD:440319	187/505 (37%)
		DEXHc_RAD54A	156..396	CDD:350825	98/244 (40%)
rdh54	NP_593038.2	HepA	<205..683	CDD:440319	187/505 (37%)
		DEXHc_RAD54	205..441	CDD:350762	98/244 (40%)