Protein Alignment okr and mit1

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_595385.1
• Gene: mit1 / 2541336
• PomBaseID: SPBP35G2.10
• Length: 1418
• Species: Schizosaccharomyces pombe
• Alignment Length: 675
• Identity: 183/675 - (27%)
• Similarity: 307/675 - (45%)
• Gaps: 115/675 - (17%)

  Fly   156 LRPHQREGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVS 220
            |.|:|.:|:.::|.    :....:.||:|||||||||:|.::.: ::|....:|.|    .:|:.
pombe   556 LMPYQLKGLNWLYL----RWYTHHPCILADEMGLGKTVQVISFI-SVLFYRHKCFP----VLVIV 611

  Fly   221 PSSLVKNWEKEFTKWLHGRLLCLPMEGGTKENTIRAL-EQFSMTSAR----LGTPVLLISYETFR 280
            |.:.|.|||:|..||  ...|.:.:..|:::|  |:| ..:.:.:.:    :.|.||:||.....
pombe   612 PHATVANWERELKKW--APFLQINVLVGSEKN--RSLVRDYRLINQKDPKHVSTHVLVISASNVE 672

  Fly   281 IYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNP 345
            ....:|.|::..::|.|||.||||..:..:..|..:|:..::||:|||:||::.|.::|:.|:||
pombe   673 REISLLRKFQWKVLIVDEGQRLKNDQSSLFYYLSSVKSDFKLLLTGTPLQNNVRELFNLLQFLNP 737

  Fly   346 EMLGTAAVFKRNFESAILRGQNTDSTEQERQRAI---EKTQELIGLVDQCIIRRTNQILTKYLPV 407
            ..:..|                    |.|::.:|   ||..||..::....:||....:....|.
pombe   738 MKINAA--------------------ELEKRYSIIDTEKVTELHQILKPFFLRRVKSEVLDNFPT 782

  Fly   408 KFEMVICAKLTAIQLELYTNFLKSD--QVRRSLADCNEKAS----LTALADI-TTLKKICSHPDL 465
            |.|::|...:|.:|..||.:.|..:  .:|......|..:|    .|:|.:| ..|:|..:||.:
pombe   783 KVEVIIPLSMTPVQKGLYKSILSKNLSLLRNITGYANTSSSGGQRTTSLNNILMQLRKTLAHPYI 847

  Fly   466 IYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLD 530
            ....:..|...:|.:...|          .|.|.||::|..::..:...|: :::|.|.:.|.||
pombe   848 YSPDIEDRNLPYELAMRSL----------EEASCKFLILRLLVPKLITRGH-RILLFSQFIQQLD 901

  Fly   531 LFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFD 595
            :.|.....:...:.|.||..|..:|...:|.||.|.|:...|:||::|||.|:||..|:.:.:.|
pombe   902 ILEDWFEYKNIAYARFDGASSEMERQSAIDSFNAPNSELSCFLLSTRAGGVGINLASADTVIILD 966

  Fly   596 PDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTII---DNNESAEK 657
            ||:||..|.||:||..|.||||...::.|....|:||||:|....|..|...|:   |.|.::||
pombe   967 PDFNPHQDMQAIARAHRYGQKKKVLVFVLTTRDSVEEKIIQNAQKKLVLDHLIVESLDQNHNSEK 1031

  Fly   658 HFTRDDLKDLFTFDANIL-SDTHDKLKCKRCVQNIQM----KPPPEDTDC--------------- 702
                 ||:.:....|..| .:..|:...|....::::    ....|||..
pombe  1032 -----DLESILRHGARALFEEAGDEPSIKYNEYSVELLISEAEKQEDTSTDESDIKSNKFGFFRV 1091

  Fly   703 --TSHLSQWYHCSNNRGLPDNILA---QAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEEKP 762
              ..|:|     ||:..:.:|:|.   ..|      |.:...|.:      .|..|.||:.....
pombe  1092 WDNKHIS-----SNHYEVKENVLVDEEDVW------SVILKQREK------DAMLEKTDETTSNR 1139

  Fly   763 ESRKRSSTPASDD------SADEDF 781
            ..|........:|      |.|.|:
pombe  1140 RLRAHHKIHYGEDLNIYDNSDDTDY 1164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	152/511 (30%)
		DEXHc_RAD54A	156..396	CDD:350825	71/247 (29%)
mit1	NP_595385.1	PHD	214..268	CDD:214584
		CD_CSD	359..426	CDD:475127
		PLN03142	546..>1086	CDD:215601	165/578 (29%)
		zf-CCCH_7	1235..1329	CDD:376012
		zf-CCCH_6	1331..1383	CDD:436598