Protein Alignment okr and Chd3

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: XP_017169944.1
• Gene: Chd3 / 216848
• MGIID: 1344395
• Length: 2111
• Species: Mus musculus
• Alignment Length: 759
• Identity: 201/759 - (26%)
• Similarity: 328/759 - (43%)
• Gaps: 162/759 - (21%)

  Fly   127 PAYTEHER---------MGMDPTKVLVH---------------VVVDPLLSNILRP--------- 158
            |.|.:|::         ||.||.:...:               ...||.:....:|
Mouse   723 PEYDDHKQSYWRHRELIMGEDPAQPRKYKKKKKELQGDGPPSSPTNDPTVKYETQPRFITATGGT 787

  Fly   159 ---HQREGVRFM-YECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVV 219
               :|.||:.:: :...:|     ...|:|||||||||:|.:..:::|.::|    .|....:|.
Mouse   788 LHMYQLEGLNWLRFSWAQG-----TDTILADEMGLGKTIQTIVFLYSLYKEG----HTKGPFLVS 843

  Fly   220 SPSSLVKNWEKEFTKWL------------HGRLLCLPMEGGTKENTIR-ALEQFSM-TSARLGTP 270
            :|.|.:.|||:||..|.            ..|.:....|...::|.|: ..:.|.| ..|::...
Mouse   844 APLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFH 908

  Fly   271 VLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTE 335
            |||.|||...|....|.......::.||.|||||:.:..::.|.|.|...::||:|||:||:|.|
Mouse   909 VLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEE 973

  Fly   336 YYSLVNFVNPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQI 400
            .:.|:||:.||.......|...|         .|.:::::   |:|..:|:|   ..::||....
Mouse   974 LFHLLNFLTPERFNNLEGFLEEF---------ADISKEDQ---IKKLHDLLG---PHMLRRLKAD 1023

  Fly   401 LTKYLPVKFEMVICAKLTAIQLELYTNFL-KSDQVRRSLADCNEKASLTALADITTLKKICSHPD 464
            :.|.:|.|.|:::..:|:.:|.:.|...| ::.:...|....|:.:.|..:.|   |||.|:||.
Mouse  1024 VFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMD---LKKCCNHPY 1085

  Fly   465 LIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGKFMLLDFMLAAIRAEGNDKVVLISNYTQTL 529
            |.  .:.|.|      ...|||.........:.|||.:||..||..::.:|: :|::.|..|:.|
Mouse  1086 LF--PVAAME------SPKLPSGAYEGGALIKSSGKLLLLQKMLRKLKEQGH-RVLIFSQMTKML 1141

  Fly   530 DLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMF 594
            ||.|.......|.:.|:||.::...|.:.:||||.|.:..|.|:||::|||.|:||..|:.:.:|
Mouse  1142 DLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIF 1206

  Fly   595 DPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTII-DNNESAEKH 658
            |.||||.||.||.:|..|.||.....|||.|...|:||:|.|....|..|:..:: ....|....
Mouse  1207 DSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKAGS 1271

  Fly   659 FTRDDLKDLFTF-----------------DANILSDTHDKLKCKRCVQNIQMKPPPEDTD---CT 703
            .::.:|.|:..|                 |::::.  :|.....|.:...|  ...||||   ..
Mouse  1272 MSKQELDDILKFGTEELFKDENEGENKEEDSSVIH--YDNEAIARLLDRNQ--DATEDTDVQNMN 1332

  Fly   704 SHLSQW----YHCSNNRGL----------PDNILAQAWMDCKCVSFVFHHRSQAQEIV------- 747
            .:||.:    |.......:          .:|:....|     ...:.||..|.||.:
Mouse  1333 EYLSSFKVAQYVVREEDKIEEIEREIIKQEENVDPDYW-----EKLLRHHYEQQQEDLARNLGKG 1392

  Fly   748 ----------PSAEEEATDQPE-------------EKPESRKRS 768
                      .:|:|:..:|.|             |:||.|::|
Mouse  1393 KRVRKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQS 1436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137
		HepA	<156..650	CDD:440319	161/522 (31%)
		DEXHc_RAD54A	156..396	CDD:350825	74/266 (28%)
Chd3	XP_017169944.1	CHDNT	200..253	CDD:462357
		PHD1_CHD_II	434..476	CDD:277006
		PHD2_CHD_II	510..552	CDD:277007
		CD1_tandem_CHD3-4_like	557..635	CDD:349314
		CD2_tandem_CHD3-4_like	680..734	CDD:349309	3/10 (30%)
		PLN03142	771..>1325	CDD:215601	169/593 (28%)
		DEXHc_CHD3	788..1019	CDD:350813	73/254 (29%)
		DUF1087	<1366..1409	CDD:461922	8/47 (17%)
		CHDII_SANT-like	1430..1569	CDD:461920	4/7 (57%)
		PHA03169	1589..>1759	CDD:223003
		CHDCT2	1791..1917	CDD:462358