Protein Alignment okr and F53H4.6

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001359661.1
• Gene: F53H4.6 / 181672
• WormBaseID: WBGene00010011
• Length: 922
• Species: Caenorhabditis elegans
• Alignment Length: 857
• Identity: 178/857 - (20%)
• Similarity: 311/857 - (36%)
• Gaps: 221/857 - (25%)

  Fly    11 GPLRPESRHSFTPPLLKKNKRSCQQELEREQELDRRRLGALRDASNTSE-----------LPLP- 63
            |.|...:|::        ||.........||..|:.....:...:|||.           ||.|
 Worm    56 GQLNISARNA--------NKNRANASERNEQRPDKNNDAIVIKPTNTSNDRKSLKRRPDALPDPP 112

  Fly    64 -----IRFTANSEYELAIAKVLARK---FKVP----MDN------------YVPDYGGKRVLGVR 104
                 .:.|.:|:.::.|.:....|   |:.|    .||            |:|:   .|.. |.
 Worm   113 IEKRHKQTTVDSDDDVMIIERTPEKTNSFETPDSIDDDNMSDDMRCRNTFPYIPE---SRTT-VT 173

  Fly   105 RCI-------SRRPLHDPMACNALVLFHPPAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQR- 161
            |.:       ||:|.::.:....|     ....:|.|.|         :|:|   .|:|...::
 Worm   174 RMVRSEDGKESRKPCNEHLTTKWL-----QTQMDHNRGG---------IVID---ENVLNKPRKA 221

  Fly   162 -EGVRFMYECVEGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLV 225
             :|..|:....|..|...|..      ||                        :.|::|.|.:.:
 Worm   222 WQGASFLSSIFESFRKFKNSA------GL------------------------SSALIVCPEAKL 256

  Fly   226 KNW----EKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGTP---VLLISYETFRIYA 283
            ..|    ..:|.   :.|:..|.....|...|....:.|.........|   |||.::..|..:.
 Worm   257 SEWMLAIRHQFD---YARIFVLHKASTTGHETDYVEKIFQDLKETKKIPFGAVLLTTFAEFGKHE 318

  Fly   284 EILCKYEVGMVICDEG-----HRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFV 343
            :.:..::..:|..|:|     .:::|.    .:.:..|||..|.:.:.|.:::.|.|.:..|:||
 Worm   319 KAIVDHQWQLVYLDQGLFEMTRQMRNQ----IEGMKKLKTPNRFIFTDTSVRDRLEELWWNVDFV 379

  Fly   344 NPEMLGTAAVFKRNFESAILRGQNTDSTEQERQRAIE----KTQELIGLVDQCIIRRTNQILTKY 404
            .|..|.....|:.||::.|..|...|:|.:|...|.|    ....|..|:...:|:..|....:.
 Worm   380 FPGRLSDYKTFQTNFQNVIEIGCRLDATPEEASTAYECIVALHVALKPLILSRLIKNPNDWFCRR 444

  Fly   405 LPVKFEM-----VICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTLKKICSHPD 464
            ...|.|:     :|| .|:..|......:.:||:|:..|     :.|..|...:..|..||.||.
 Worm   445 EISKKEVEHIKDIIC-PLSKRQRRCLKIYKRSDEVQGIL-----RQSSAACVGLKKLTDICDHPG 503

  Fly   465 LIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGK----FMLLDFMLAAIRAEGNDKVVLISNY 525
             |::.:|...|.|.:.::               |||    |.|||..|....|    |||:.:..
 Worm   504 -IHKGVTPETKKFGSIED---------------SGKVRIVFQLLDMWLGTPGA----KVVIFTQR 548

  Fly   526 TQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRFNDPE------SDSFLFMLSSKAGGCGLN 584
            .|...:.|...::::..:.......:...|..||:.|.:..      :.|.:|.|       |:.
 Worm   549 RQVAVMLEHFMKQKRIAYCSFLKAKNAYDRENVVNYFENTTDVQILLAPSIMFKL-------GMQ 606

  Fly   585 LIGANRLFMFDPDWNPAND-EQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTI 648
            |..||::.:|||:|||.:| :......:...:.:...:.|||:.|::|:....::..:..|:|.:
 Worm   607 LKKANKVIIFDPEWNPDSDVKHTREMSFLTKKVEDVTVVRLVSEGTVEDSSYFKKLWESGLASRL 671

  Fly   649 IDNNESAEKHFTRDDLKDLFTFDANILSDTHDKLKCKRCVQNIQMKPPPE------------DTD 701
            : ::...|....|..|::..|....|.:..:|....|..::|..::...:            ||.
 Worm   672 L-SDPKFEPFVPRTTLEEFLTVRPKIKAGKNDMPVVKSHMKNRLLEYEDKQLLSSIIDTTRLDTI 735

  Fly   702 CTSHLSQWYHCSN----------NRGLP-----DNILAQAWMDCKCVSFVFHHRSQAQEIVPSAE 751
            .|...|..||.:.          ||.:.     |:.||:.|            |....:||   :
 Worm   736 RTHFTSFQYHSTTSDRIKSRDVVNRAVRSIIQIDSRLARYW------------RQMYHQIV---D 785

  Fly   752 EEATDQPEEKPE 763
            |...|.|  .||
 Worm   786 EPTLDPP--NPE 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	15/75 (20%)
		HepA	<156..650	CDD:440319	113/527 (21%)
		DEXHc_RAD54A	156..396	CDD:350825	52/257 (20%)
F53H4.6	NP_001359661.1	DEAD-like_helicase_N	195..381	CDD:475120	44/239 (18%)
		HepA	<247..655	CDD:440319	102/447 (23%)