Protein Alignment okr and pqn-15

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001367558.1
• Gene: pqn-15 / 180705
• WormBaseID: WBGene00004106
• Length: 2171
• Species: Caenorhabditis elegans
• Alignment Length: 839
• Identity: 224/839 - (26%)
• Similarity: 361/839 - (43%)
• Gaps: 167/839 - (19%)

  Fly    18 RHSFTPPLLKKNKRSCQQELERE----QEL---DRRRLGALRDASNTSELPLPIRFTAN------ 69
            |.|....:..:|||..::|::.|    |:|   |.....|:.|......|...:..|.:
 Worm  1052 RKSMQQYITNENKRIAREEMKNEKNRIQKLIQEDEEGYRAMLDEKKDQRLVYLLEQTDDYIKSLC 1116

  Fly    70 ---SEYELAIAKVLARKFKVPMDNYV-PDYGGKRVLGVRRCISRRPLHDPMACNALVLFHPPAYT 130
               .:.:.|.|..||.|      :|: .:|.|.......:.|..:..:|           ...|.
 Worm  1117 DLLKQQQNATAGSLATK------SYIRKEYDGVAEEDKVKSILDKARND-----------DDEYE 1164

  Fly   131 EHERMGMDPTKVLVHVVVD-------------PLLSNILRPHQREGVRFMYECVEGKRGNFNGCI 182
            ...:|.::......|.|.:             |.|.  |:|:|.:|:.:|   |.....|.|| |
 Worm  1165 NKTKMNIEDYYTTAHGVREEIKEQHFMMGGGNPSLK--LKPYQIKGLEWM---VSLFNNNLNG-I 1223

  Fly   183 MADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLVKNWEKEFTKW---LHGRLLCLP 244
            :|||||||||:|.:..:..|:    |.|.|....:|:.|.|.|.||:.||.||   :|     |.
 Worm  1224 LADEMGLGKTIQTIAFITYLM----EIKKTSGPFLVIVPLSTVPNWQNEFDKWAANVH-----LI 1279

  Fly   245 MEGGTKENTIRALEQFSMTSARLGTPVLLISYETFRIYAEILCKYEVGMVICDEGHRLKNSD-NL 308
            ...|.|| |.:..|.. :.|.:..  |||.::|.......:|.|.....:|.||||||||.. .|
 Worm  1280 AYKGPKE-TRKVFEPI-IKSGKFN--VLLTTFEYVIREKALLGKLRWKYMIIDEGHRLKNQHCKL 1340

  Fly   309 TYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAI-LRGQNTDSTE 372
            |.......:.:||:|::|||:||.|.|.::|:||:.|.:..:.:.|::.|.:.. ..|:..:.|:
 Worm  1341 TEMLNTRFQCQRRLLITGTPLQNKLPELWALLNFLLPSIFSSCSTFEQWFNAPFATTGEKVELTQ 1405

  Fly   373 QERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNFLKSDQVRRS 437
            :|....|.:..:::   ...::||..:.:...||.|.|.|:...::|:|..||.:..|.     .
 Worm  1406 EETMLIIRRLHKVL---RPFLLRRLKKEVESELPDKMEFVVRCDMSALQKVLYKHMQKG-----L 1462

  Fly   438 LADCNEKASLTALAD-ITTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNP----EL 497
            |.|........:|.: :..|:|:|:||.|           |||.:....:.:..:.::.    .:
 Worm  1463 LLDGKTNTGSKSLRNTMIHLRKLCNHPFL-----------FENVEESCRNFWDARFISAVDLYRV 1516

  Fly   498 SGKFMLLDFMLAAIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMSIKKRSKVVDRF 562
            |||..||..:|..::|.|: :|::....|..:.:.|.........::||||:....:|..::|:|
 Worm  1517 SGKLELLSRILPKLQATGH-RVLMFFQMTSMMTIVEDFLAGGTIQYLRLDGSTKPDERGALLDKF 1580

  Fly   563 NDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVAS 627
            |.|.|:.||||||::|||.||||..|:.:.:||.||||..|.||..|..|.|||....::||:.:
 Worm  1581 NAPNSEYFLFMLSTRAGGLGLNLQTADTVIIFDSDWNPHQDMQAQDRAHRIGQKAEVRVFRLITA 1645

  Fly   628 GSIEEKILQRQTHKKSLSSTII-----DN------------------NESAEKHFTRDDLKDLFT 669
            .|:|||||....:|.::...:|     ||                  |||.|.....:| :|:
 Worm  1646 NSVEEKILAAARYKLNVDEKVIQAGKFDNRSTGAERREILENIIKTENESEEDEEVPND-EDI-- 1707

  Fly   670 FDANILSDTHD------KLKCKRCVQNIQMKPPP----EDTDCTSHLSQWYHCSNNRGLPDNILA 724
              .:|||.:.:      |:..:|.......|..|    ||.                 :|.:||.
 Worm  1708 --NDILSRSEEEFELFQKMDQERFENEQAQKAKPRLVGEDE-----------------IPRDILR 1753

  Fly   725 QAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEEKPESR--KRSSTPASDDSADEDF 781
            .|              .:...|..:.||......|..|.||  :|....::|..:|:.|
 Worm  1754 AA--------------DETDYIEKAKEEGRVPYLEVMPGSRRTRREVDYSADTMSDDKF 1798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	9/50 (18%)
		HepA	<156..650	CDD:440319	162/508 (32%)
		DEXHc_RAD54A	156..396	CDD:350825	79/244 (32%)
pqn-15	NP_001367558.1	Med15	<1..>288	CDD:312941
		Med15	<372..>592	CDD:312941
		HSA	1011..1083	CDD:214727	9/30 (30%)
		PLN03142	1062..>1726	CDD:215601	202/724 (28%)
		SnAC	1727..1799	CDD:464219	20/103 (19%)