Protein Alignment okr and F54E12.2

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_502137.1
• Gene: F54E12.2 / 178054
• WormBaseID: WBGene00010061
• Length: 1091
• Species: Caenorhabditis elegans
• Alignment Length: 850
• Identity: 197/850 - (23%)
• Similarity: 328/850 - (38%)
• Gaps: 232/850 - (27%)

  Fly     4 SLAPSQRGPLRPES-------RHSFTPPLLKKNK----------------RSCQQELEREQELDR 45
            |..|..:.|..|.|       :.|:...|.||||                |..:|..|.:.|::|
 Worm   284 SRPPEPQRPRLPTSPINSEYAKLSYKELLAKKNKVMGLISLSLDLPDGGRRVIKQFQELDDEVER 348

  Fly    46 RRLGALRDASNTSELPLPIRFTANSEYELAIAKVLARKFKVPMDNYV-PDYGGKRVLGVRRCISR 109
            |:           |:.|......:.|.:    ::...:...|....| |.:....|:.....:.:
 Worm   349 RK-----------EMGLAEEIVDDDEDD----EIFVIEDDEPSHRQVAPKFPSGSVMTQNGLLPK 398

  Fly   110 RPLHDPMAC------------NALVLFHPPAYTEHERMGMDPTKVL------VHVVVDPL-LSNI 155
            |.:.||:..            |..::.......:::|:.:...:|:      .|.:.|.. |::.
 Worm   399 RHIVDPLKAPQPDFNAMLEKDNKKMMSGKMTDEKYKRIQLVSDRVVRQLAEATHTIPDETELTDT 463

  Fly   156 -------LRPHQREGVRFM-YECVEGKRGNFNGCIMADEMGLGKTLQCVTLV------------- 199
                   |.|||:.|:.:| :...:.:.|.    |:||:|||||||..::|:
 Worm   464 PKGFKLELMPHQKAGLTWMRWRETQPQPGG----ILADDMGLGKTLSMISLIAHQKAARRARRED 524

  Fly   200 ----------WTLLRQG--PECKPTINKAIVVSPSSLVKNWEKEFTKWLHGRLLCLPMEGGTKEN 252
                      ..:..||  |.     |..::|:|:||:..|:.|..:.|...:|...|..|||
 Worm   525 GNDDKDKEKRKVVKEQGLIPS-----NGTLIVAPASLIHQWDAEIDRRLDDSVLSTYMFHGTK-- 582

  Fly   253 TIRALEQFSMTSARLGTPVLLISYETFRIYA---------------------------------- 283
                 :|..:.:.||....::|:  ||.:.|
 Worm   583 -----KQRDIDARRLARYDVVIT--TFNLIANELIEKIRTKSKADDSSDGESDSNHTGIRRAVGK 640

  Fly   284 --EILCKYEVGMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPE 346
              .:|.:.....||.||.|.:||..:|..:|:..|....|..||||||.|:|.:.||||.|:...
 Worm   641 DDSVLAQICWSRVILDEAHTIKNRQSLASKAVCRLSAFSRWCLSGTPIHNNLWDLYSLVRFLRIR 705

  Fly   347 MLGTAAVFKRNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQ-CIIRRTNQILTKYLPVKFE 410
            .......:|.:.       ........:|...:.|...|....|| |.:  |||.|.: ||.|..
 Worm   706 PFSDDKYWKESI-------MPMKPIMADRVNLLTKNLLLRRTKDQTCAV--TNQKLVQ-LPPKNV 760

  Fly   411 MVICAKLTAIQLELYTNFLKSDQ--VRRSLADCN------------------------------- 442
            .|...:|...:.:.|...:::.:  |::.|.|.|
 Worm   761 EVHELELDGDEAQAYEIMMEAAKKFVKKLLQDSNDMKNHGFIPRRNRRAGKEGEVQNPFNFGPRD 825

  Fly   443 -------EKASLTALADITTLKKICSHPDLIYEKLTAREKGFENSQNVLPSNYKPKDLNPELSGK 500
                   ||.|...:. :..|::.|.|.::....:...........|...:|.  .||| ||..|
 Worm   826 LAAGSNFEKMSCVLML-LLRLRQACVHFNITKTGVDMDAFSLIGGDNAEEANV--DDLN-ELLEK 886

  Fly   501 FMLL----------------------DFMLAAIR---------AEGNDKVVLISNYTQTLDLFEQ 534
            .|.:                      |::...|:         .|..:|||::|.:|..|:|.|.
 Worm   887 TMNMTLGNGDNEERDKPRATTRIFDPDYLSCKIKNTLEIVENIMEKKEKVVIVSQWTSVLNLIEI 951

  Fly   535 LARKRKYGFVRLDGTMSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWN 599
            ..:...:.:..:.|.:.:|.|.:.||.||..:..:.:.:||..|||.||||.|.|.|.|.|..||
 Worm   952 HIKSSGFKYTSITGQVLVKDRQERVDSFNREKGGARVMLLSLAAGGVGLNLTGGNHLVMVDLHWN 1016

  Fly   600 PANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEKH-FTRDD 663
            ||.::||..|::|.||||..:|:|||..|:||::::..|..|.:|:|:::|.|.:.:.: .|..|
 Worm  1017 PALEQQAFDRIYRMGQKKDVFIHRLVTKGTIEQRVVMLQKDKVALASSVLDGNATRKMNKLTTAD 1081

  Fly   664 LKDLF 668
            :|.||
 Worm  1082 IKMLF 1086

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	8/62 (13%)
		HepA	<156..650	CDD:440319	157/627 (25%)
		DEXHc_RAD54A	156..396	CDD:350825	73/302 (24%)
F54E12.2	NP_502137.1	HepA	<458..1067	CDD:440319	158/640 (25%)