DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment okr and rad54b

DIOPT Version :9

Sequence 1:	NP_476661.1	Gene:	okr / 33507	FlyBaseID:	FBgn0002989	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_001121509.1	Gene:	rad54b / 100158622	XenbaseID:	XB-GENE-5839240	Length:	897	Species:	Xenopus tropicalis

Alignment Length:	676	Identity:	275/676 - (40%)
Similarity:	393/676 - (58%)	Gaps:	54/676 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   110 RPLHDPMACNALVLFHPPAYTEHERMGMDPTKV-LVHVVVDPLLSNILRPHQREGVRFMYECVEG 173
            :|.|||.|.||.|:   |..|:|.:...:.|.: :|.|||||.|:..|||||:||:.|:||||.|
Frog   237 KPRHDPCAPNAFVM---PKPTQHHQWAYNKTGLPIVDVVVDPYLAVHLRPHQKEGILFLYECVMG 298

  Fly   174 KRGNFN-GCIMADEMGLGKTLQCVTLVWTLLRQGP-ECKPTINKAIVVSPSSLVKNWEKEFTKWL 236
            .|.|.. |.|:||||||||||||::|:|||:|||| ..||.|.||::|:|.||||||.|||.|||
Frog   299 MRVNERFGAILADEMGLGKTLQCISLIWTLIRQGPYGGKPVIKKALIVTPGSLVKNWRKEFQKWL 363

  Fly   237 HGRLLCLPMEGGTKENTIRALEQFSMTSARLGTP---VLLISYETFRIYAEILCKYEVGMVICDE 298
                       ||:...:.|::|.......:.:|   ||:||||......|.:...:..:|||||
Frog   364 -----------GTERIRVFAVDQDHKVEEFMKSPLYSVLIISYEMLLRCLEQIQSLDFDVVICDE 417

  Fly   299 GHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFVNPEMLGTAAVFKRNFESAIL 363
            ||||||:...|..||..|...:|::|||||:||||.|:::|:.||||..||:.:.:::.||..|:
Frog   418 GHRLKNTSIKTTSALASLTCSKRIILSGTPVQNDLQEFFALIEFVNPAALGSLSTYRKIFEEPII 482

  Fly   364 RGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTNQILTKYLPVKFEMVICAKLTAIQLELYTNF 428
            |.:...:|.:|:....|:..||..|....|:|||.:::.|:||.|.|.::..:.:..||:||...
Frog   483 RSREPTATTEEKNLGEERAAELARLTGLFILRRTQEVINKFLPPKIESIVFCRPSQFQLDLYRKL 547

  Fly   429 LKSDQVRRSLADCNEKASLTALADITTLKKICSHPDLIYEKLTAREKG--------FENSQNVLP 485
            |.|..|:..|....|  |...|..|..|||:|:||.|::..:..:...        :|:...|.|
Frog   548 LNSRTVKSCLLGSGE--SSPHLVCIGALKKLCNHPFLLFRTIQGKSTNPDQDEHNLYESVAEVFP 610

  Fly   486 SNYKPKDLNPELSGKFMLLDFMLAAIR-AEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGT 549
            .:|....::...|||.::|..:|:.|| ...:::|||:|||||||::.:.|..:..|...||||.
Frog   611 QDYDGAKISESESGKLLVLSNLLSRIRELSPSERVVLVSNYTQTLNILQDLCNQHGYSCTRLDGQ 675

  Fly   550 MSIKKRSKVVDRFNDPESDSFLFMLSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDG 614
            ..:.:|..:||.||...|..|:|:|||||||.|||||||:.|.::|.|||||||.||||||||||
Frog   676 TPVTQRQHIVDGFNSKYSTDFIFLLSSKAGGVGLNLIGASHLILYDLDWNPANDIQAMARVWRDG 740

  Fly   615 QKKPCYIYRLVASGSIEEKILQRQTHKKSLSSTIIDNNESAEK-HFTRDDLKDLFTFDANILSDT 678
            |:...:||||:.:||:||||.|||..|:.||..::|..:.:|. .|:.|:|::|||...:....|
Frog   741 QRHTVHIYRLLTTGSLEEKIYQRQISKQGLSGAVVDLTKKSEHIRFSLDELRNLFTLHEDTDCVT 805

  Fly   679 HDKLKCKRCVQNIQMKPPPE----DTDC--------------TSHLSQWYHCSNNRGLPDNILAQ 725
            ||.|:|...:.|......|:    ...|              .|.|.||.|.|..:...|..|.
Frog   806 HDLLQCDCTITNCHSDGSPQKPLIHRSCQLGLHQDQLNKNFSMSELMQWKHFSGQQNTEDPFLQ- 869

  Fly   726 AWMDCKCVSFVFHHRSQAQEIVPSAE 751
              |..:.:||||.:.:.:| :.|::|
Frog   870 --MGKEHISFVFQNTTNSQ-VNPTSE 892

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	SNF2_N	159..466	CDD:278600	135/311 (43%)
		DEXDc	179..328	CDD:238005	72/153 (47%)
		HELICc	493..622	CDD:238034	65/129 (50%)
rad54b	NP_001121509.1	SNF2_N	284..583	CDD:278600	135/311 (43%)
		DEXDc	306..447	CDD:238005	72/151 (48%)
		Helicase_C	623..740	CDD:278689	62/116 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D93727at2759
OrthoFinder	1	1.000	-	-		FOG0001533
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920