Protein Alignment okr and ercc6l

DIOPT Version :10

• Sequence 1: NP_476661.1
• Gene: okr / 33507
• FlyBaseID: FBgn0002989
• Length: 784
• Species: Drosophila melanogaster
• Sequence 2: NP_001093563.2
• Gene: ercc6l / 100005291
• ZFINID: ZDB-GENE-060531-56
• Length: 1444
• Species: Danio rerio
• Alignment Length: 772
• Identity: 209/772 - (27%)
• Similarity: 361/772 - (46%)
• Gaps: 132/772 - (17%)

  Fly    36 ELEREQELDR-RRLGALRDASNTSELPLPIRFTANSEYELAIAKVLARKFKVPMDNYVPDYGGKR 99
            :.|:..:.|| |:.|  ::|:...|||..:..     ::||.....:.|.|            ||
Zfish    20 DTEKMGKYDRYRQKG--KEAALNGELPHALEL-----FQLAYQLQPSEKLK------------KR 65

  Fly   100 VLGVRRCISRRPLHDPMACNALVLFHPPAYTEHERMGMDPTKVLVHVVVDPLLSNILRPHQREGV 164
            :..::..|.|....|..        ....:......|:...|.|...:.|         ||:|||
Zfish    66 IQAIQDLIQREDEEDEE--------EEEEFVNVNNSGLKLYKGLYDKLYD---------HQKEGV 113

  Fly   165 RFMYECV-EGKRGNFNGCIMADEMGLGKTLQCVTLVWTLLRQGPECKPTINKAIVVSPSSLVKNW 228
            .|:|... :|::|.    |:||:||||||:|.::.:     .|.......|..::|.|:||:|||
Zfish   114 AFLYSLYRDGRKGG----ILADDMGLGKTIQVISFL-----SGMYDAELANHTLLVMPTSLIKNW 169

  Fly   229 EKEFTKWLHGRLLCLPMEGGTKENTIRALEQFSMTSARLGT--PVLLISYETFRIYAEILCKYEV 291
            .:||.||..| :......|.:|....|.||:.......:.|  .:|:.:||..........|::
Zfish   170 VREFAKWTPG-MRVKEFHGSSKTERNRNLERIQRKGGVIITTYQMLINNYEQLGSNGHREFKWD- 232

  Fly   292 GMVICDEGHRLKNSDNLTYQALMGLKTKRRVLLSGTPIQNDLTEYYSLVNFV-NPEMLGTAAVFK 355
             .||.||.|::|.|...|.::...:..|.||||:|||:||:|.|.::|.:|. ...:|||:..||
Zfish   233 -YVILDEAHKIKTSSTKTAKSAHAIPAKNRVLLTGTPVQNNLREMWALFDFACQGSLLGTSKTFK 296

  Fly   356 RNFESAILRGQNTDSTEQERQRAIEKTQELIGLVDQCIIRRTN-QILTKYLPV------------ 407
            ..:|:.|.|.:..|:|..|:...:..:|.|..::....:|||. .:..|.|.:
Zfish   297 TEYENPITRAREKDATPGEKALGLRISQNLTDIIKPYFLRRTKADVQQKKLKLEEGFEEEEDQEN 361

  Fly   408 ----------------KFEMVICAKLTAIQLELYTNFLKSDQVRRSLADCNEKASLTALADITTL 456
                            |.::::...|:::|.::|..|:..||::..|.     .:.:.||::|.|
Zfish   362 KCPNAREGVEMPSLTRKNDLIVWTYLSSVQEDIYNKFISLDQIKELLT-----TTRSPLAELTVL 421

  Fly   457 KKICSHPDLIYEKLTAR---EKGFEN-------SQNVLP--SNYKPKDLNPELSGKFMLLDFMLA 509
            ||:|.||.|:.::...:   |:|.::       |::.:.  .|.....|..| |||...:..::.
Zfish   422 KKLCDHPRLLSQRAVIQLGLERGSDSELVHSDESESAVSQIDNISDHTLIEE-SGKLQFVVSLME 485

  Fly   510 AIRAEGNDKVVLISNYTQTLDLFEQLARKRKYGFVRLDGTMS-IKKRSKVVDRFNDPESDSFLFM 573
            .:|.||: :.::.|...:.||:.|::.|.|.:..:|||||:: :.:|.|.:..|...:..: :|:
Zfish   486 CLREEGH-RTLIFSQSRKMLDIMERVLRNRNFRLLRLDGTVTQLAEREKRISLFQTDKRYT-IFL 548

  Fly   574 LSSKAGGCGLNLIGANRLFMFDPDWNPANDEQAMARVWRDGQKKPCYIYRLVASGSIEEKILQRQ 638
            |:::.||.|:.|.||||:.:|||.||||.|.||:.|.:|.||.:...||||:..|::||||.:||
Zfish   549 LTTQVGGVGITLTGANRVVIFDPSWNPATDAQAVDRAYRIGQTENVIIYRLITCGTVEEKIYRRQ 613

  Fly   639 THKKSLSSTIIDNNESAEKHFTRDDLKDLFTFDANILSDTHDKLKCKRCVQNIQMKPPPEDTDCT 703
            ..|.||......:.::..::|::.:|::||..:....|.|..:|      |.:..:....||...
Zfish   614 VFKDSLIRQTTGDKKNPFRYFSKQELRELFKLEDTRSSSTQQQL------QAMHAQSRRSDTSLD 672

  Fly   704 SHLSQWYHCSNNRGLPDNILAQAWMDCKCVSFVFHHRSQAQEIVPSAEEEATDQPEE 760
            .|::: .|.....|:.|                 |.....:|  |:|:|   |.||:
Zfish   673 HHIAR-LHSMEMFGISD-----------------HDLMFTKE--PAADE---DDPED 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
okr	NP_476661.1	Rad54_N	<76..>126	CDD:430137	7/49 (14%)
		HepA	<156..650	CDD:440319	165/539 (31%)
		DEXHc_RAD54A	156..396	CDD:350825	78/243 (32%)
ercc6l	NP_001093563.2	TPR 1	27..60		10/39 (26%)
		DEAH box	237..240		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	647..669		4/27 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	778..804
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	928..999
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1028..1047
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1056..1076
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1089..1133
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1175..1336
		TPR 2	1395..1428