Protein Alignment Chd1 and chd6

DIOPT Version :9

• Sequence 1: NP_001245851.1
• Gene: Chd1 / 33505
• FlyBaseID: FBgn0250786
• Length: 1900
• Species: Drosophila melanogaster
• Sequence 2: XP_699360.5
• Gene: chd6 / 570753
• ZFINID: ZDB-GENE-130530-559
• Length: 2953
• Species: Danio rerio
• Alignment Length: 1635
• Identity: 459/1635 - (28%)
• Similarity: 717/1635 - (43%)
• Gaps: 375/1635 - (22%)

  Fly    77 EPEDKSLS---VAGFPPTAAAAQADSKTNGFTDDQEDSSSDGSSGSDSDSDAEGPSDQ---RNQS 135
            :.:||.:|   |....|:|||:.|..:      :.:.:...|..|.:......||.:.   ..:.
Zfish    22 QKKDKQMSASYVLKHTPSAAASNASDQ------NAQTTFPIGHLGKEQLRIIGGPPNHCMAHPKH 80

  Fly   136 INNANTSSSL-PKPEQNEEED--NETEAGQQQPASDASADE-SSDSSANVSPTSSSSSSEEEEED 196
            ...|.:|.|| |....|||:|  ..|:..:::...|....| ..|..:|..|   ....::|.::
Zfish    81 SGPAVSSHSLRPSMINNEEDDGGGGTKVKKKRRKKDKKESEWHEDGQSNAKP---KRREQKEGKE 142

  Fly   197 YRPKRTRQARKPPTAAEKSKKAPAPKNKKKTWDSDESDESEDSDDEVSTAQKRKPAATTSRSKLA 261
            ..|::|:.|::...  .|.:.|.|.|..||.        .:..|.:|.|..|.: .||.:.||..
Zfish   143 ILPRKTKTAKEQKD--HKKRDAKAQKEVKKV--------KKGQDVKVKTLAKNQ-CATHTPSKRG 196

  Fly   262 QQQQRRRVKP--------------FSSEDSDDDDASKRCAT-------------RRKGAAVSYKE 299
            ::.:.:...|              ....:|||..:....||             ||.|..|..::
Zfish   197 RKPKEQGAMPPEKKKKGKRKSDAVLEMVESDDTASLSTLATGGEESTDPMDNTKRRSGRQVKRRK 261

  Fly   300 ASEDEATDSEDLLEFEY--DESQ--------------AATTAATAEE--EEKCETIERILAQRAG 346
            .:||        |:|:.  |:.:              ::|.|..|||  |::...||:||:.|.
Zfish   262 YNED--------LDFKVVDDDGETIAVLGSGRIAAMSSSTLAWQAEEPPEDEANIIEKILSVRT- 317

  Fly   347 KRGCTGNQTTIYAIEENGFDPHAGFDEKQTPDAETE--AQFLIKWKGWSYIHNTWESEATLRDMK 409
                                    .:::..||...|  .:|.:|::.:||:|..|   |||.:::
Zfish   318 ------------------------VNKEMAPDEPPEEMEEFYVKYRNFSYLHCKW---ATLEELE 355

  Fly   410 AKGMKKLDNFIKK-EKEQAYWRRYAGPEDIDYFECQLELQHELLKSYNNVDRIIAKGSKPDDGTE 473
            ..  .::...||: ..:||..:......|.|.|.          ..|..|||::......|..|.
Zfish   356 KD--PRIHQKIKRFRNKQAQMKHIFTEPDEDLFN----------PDYIEVDRVLEIAITTDTETG 408

  Fly   474 E----YLCKWQSLPYAESTWE-----DAALVLRKWQRCAEQFNDRESSKCTPSRHCRVIKYRP-- 527
            |    ||.||.||.|.|||||     |...:        ::|  .|..|....:|..    ||
Zfish   409 EEVTHYLVKWCSLSYEESTWELQEDVDPVKI--------KEF--EELKKVPEMKHVE----RPLP 459

  Fly   528 -KFSRIKNQPEFLSSGLTLRDYQMDGLNWLLHSWCKENSVILADEMGLGKTIQTICFLYSLFKIH 591
             ::.:::...:: .:|..||:||::|:||||.:|....:.|||||||||||||:|.|||.:| :.
Zfish   460 EQWQKLEKSRDY-RNGNQLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLYEIF-LM 522

  Fly   592 HLYGPFLCVVPLSTMTAWQREFDLWAPDMNVVTYLGDIKSRELIQQYEWQFES------SKRLKF 650
            .|.||||.:.||||:|.|:|||..|. :|||:.|.|...||::|.|||.....      |...||
Zfish   523 GLRGPFLIIAPLSTITNWEREFRTWT-EMNVIVYHGSQISRQMILQYEMYHRDEQGNIMSGEFKF 586

  Fly   651 NCILTTYEIVLKDKQFLGTLQWAALLVDEAHRLKNDDSLLYKSLKEFDTNHRLLITGTPLQNSLK 715
            ..::||:|:::.|...|..:.|..:::||||||||.:..|.:.||..:..|::|:||||||||::
Zfish   587 QGVITTFEMIMADCPELKKINWRCVVIDEAHRLKNRNCKLLEGLKLMNLEHKVLLTGTPLQNSVE 651

  Fly   716 ELWALLHFIMPDKFDTWENFEVQHGNAE-DKGYTRLHQQLEPYILRRVKKDVEKSLPAKVEQILR 779
            ||::||:|:.|.:|.:...|..:.|:.: ::...:|...|:|.:|||:|.||||:|..|.|.|:.
Zfish   652 ELFSLLNFLEPSQFPSETTFLEEFGDLKTEEQVKKLQAILKPMMLRRLKDDVEKNLAPKEETIIE 716

  Fly   780 VEMTSLQKQYYKWILTKNFDALRKG-KRGSTSTFLNIVIELKKCCNHAALIRPSEFELM-----G 838
            ||:|::||:||:.||.|||..|.|| .:.:....:|.::||:|||||..||..:|.:::     .
Zfish   717 VELTNIQKKYYRAILEKNFAFLAKGANQHNMPNLINTMMELRKCCNHPYLITGAEEKILESFRKT 781

  Fly   839 LQQDEA---LQTLLKGSGKLVLLDKLLCRLKETGHRVLIFSQMVRMLDVLADYLQKRHFPFQRLD 900
            ...|.|   ||.:::.:|||||:||||.:|...||:||:||||||.||:|.|||.:|.:.::|:|
Zfish   782 YSSDAADFQLQAMIQAAGKLVLIDKLLPKLLAGGHKVLVFSQMVRCLDILEDYLIQRRYTYERID 846

  Fly   901 GSIKGEMRRQALDHFNAEGSQDFCFLLSTRAGGLGINLATADTVIIFDSDWNPQNDLQAQARAHR 965
            |.::|.:|:.|:|.|:...|..|.|||.||||||||||..|||.||||||||||||||||||.||
Zfish   847 GRVRGNLRQAAIDRFSKVDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHR 911

  Fly   966 IGQKNQVNIYRLVTARSVEEQIVERAKQKMVLDHLVIQRMDTTGRTVLDKSGNGHSSNSNPFNKD 1030
            |||...|.:|||:|..|.|.::.::|..|:.||..|:|.::..|      |.||    ....:|.
Zfish   912 IGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKG------SLNG----VQQLSKM 966

  Fly  1031 DLSAILKFGAEELFKDEQEHDDDLVC--DIDEILRRAETRNEDPEMPADDLLSAFKVASIAAFEE 1093
            ::..:|:.||.....|| |.:....|  |||:||:|   |.:...:.::...|.|..||..:...
Zfish   967 EVEDLLRKGAYGALMDE-EDEGSKFCEEDIDQILQR---RTQTITIQSEGKGSTFAKASFVSSGN 1027

  Fly  1094 EPSDSVSKQDQNAAGEEDDSKDWDDIIPEGFRKAID---DQERAKEMEDLYLPPRRKTAANQNEG 1155
            ....|:           ||...|     :.:.|..:   |.:..||...:..|..||...:.|..
Zfish  1028 RTDISL-----------DDPNFW-----QKWAKIAELEIDSKAEKESLVIDTPRVRKQTRHYNSF 1076

  Fly  1156 KRGAGKGGKGKQQADDSGGDSDYELGSDGSGDDGRPRKRGRPTMKEKITGFTDAELRRFIRSYKK 1220
            :             ||...:.. ||.||   .:.||.:..|.:.:.          ||::|:
Zfish  1077 E-------------DDELMEFS-ELDSD---SEERPCRTRRLSDRN----------RRYLRA--- 1111

  Fly  1221 FPAPLHRMEAIACDAEL------QEKPLAELKRLGEMLHDRCVQFL----------HEHKEEESK 1269
                    |....:..|      :.|.:....|....|.:|.::.|          |...:::.|
Zfish  1112 --------ECFRVEKNLLIFGWGRWKDILNHGRFKWHLAERDMEVLCRALLVYCVRHYKGDDKIK 1168

  Fly  1270 TAATD-ETP---------------------GAKQRRARATFS---VKLGGVSFNAKKLLACEQEL 1309
            :...| .||                     |.|.::.:...|   :|      ||..|..|..|:
Zfish  1169 SFIWDLITPTEDGHNQALQNHSGLSAPVPRGRKGKKLKNQLSPPELK------NADWLAHCNPEV 1227

  Fly  1310 ------------QPLN--------------EIMPSMPEERQQWSFNIKTRAPVFDVD-------- 1340
                        |..|              |::.....:..:...:.|....:.|:|
Zfish  1228 VLQDDSYKKHLKQHCNKVLLRVRMLYYLKVEVLGDAATQALEGIPSSKLEVTLPDIDYIEIPTIW 1292

  Fly  1341 WGIEEDTKLLCGIYQYGIGSWEQMKLDPTLKLTDKILLNDTRKPQAKQLQTRAEYLLKIIKKNVE 1405
            |..|.|..||.|::::|...:..|:.||.|...:::.:.|......:|
Zfish  1293 WDAEADKSLLIGVHKHGYERYNAMRADPALCFLERVGMPDVTALTVEQ----------------- 1340

  Fly  1406 LTKGGQRRQRRPRA-SRANDAKAASQSASSTIDAKPHDGEDAAGDARTVAESSNSQVD---PSTA 1466
              .|.:.....|.. |::::.|..:...|..::.|....|:...|  ..|::.|....   .|.|
Zfish  1341 --SGAETPSDAPDGISKSDEIKEENHVKSEELEEKVEIKEEPMSD--ETAKNDNMVTGCFVASLA 1401

  Fly  1467 SPHNAPATEQHGD---PAKKAKKSKARSKKTSASDNNGNKPM---------------------HF 1507
            ....|...|| |.   ||..|..::.|...|:.......:|:                     |.
Zfish  1402 GDLTAELMEQ-GRIQWPAGSALTARLRRLITAYQRYTRREPLRHDFLLHEGIAPVAWQIGEFRHC 1465

  Fly  1508 TANNEPRALE 1517
            |...:|..||
Zfish  1466 TTEPDPLFLE 1475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd1	NP_001245851.1	CHROMO	374..422	CDD:237991	13/49 (27%)
		Chromo	458..509	CDD:278797	20/59 (34%)
		SNF2_N	548..829	CDD:278600	129/288 (45%)
		DEXDc	564..709	CDD:238005	68/150 (45%)
		Helicase_C	852..967	CDD:278689	73/114 (64%)
		DUF4208	1521..1610	CDD:290618
		DUF3824	1795..>1894	CDD:289625
chd6	XP_699360.5	CHROMO	309..370	CDD:237991	19/90 (21%)
		Chromo	392..445	CDD:278797	20/62 (32%)
		SNF2_N	480..767	CDD:278600	129/288 (45%)
		DEXDc	496..645	CDD:238005	68/150 (45%)
		Helicase_C	799..913	CDD:278689	73/113 (65%)
		BRK	2562..2606	CDD:197800

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0384
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810