Protein Alignment Chd1 and rad-54.B

DIOPT Version :10

• Sequence 1: NP_001245851.1
• Gene: Chd1 / 33505
• FlyBaseID: FBgn0250786
• Length: 1900
• Species: Drosophila melanogaster
• Sequence 2: NP_001255913.1
• Gene: rad-54.B / 190999
• WormBaseID: WBGene00013792
• Length: 833
• Species: Caenorhabditis elegans
• Alignment Length: 842
• Identity: 221/842 - (26%)
• Similarity: 355/842 - (42%)
• Gaps: 179/842 - (21%)

  Fly   366 DPHAGFDEKQTPDAETEAQFLIKW-KGWSYIHNTWESEATL--------------RDM--KAKGM 413
            |.:.|.|   ||.||. |:|::.: |..:..|..||.:..|              ||:  ::..:
 Worm     9 DSYEGND---TPSAEI-ARFVVLYGKASTRKHKIWEGDGLLVCFTDSCLLKSEDERDVICRSSAL 69

  Fly   414 KKLDNF-------IKKEKEQAYWRRYAGPEDIDYFECQLELQHELL-----KSYNNVDRIIAKGS 466
            |.||..       |.....:...|...||........:.|:|..:.     .|.|..:|.....|
 Worm    70 KGLDQLEDGRIINIGSWSVEIQERIATGPPQKPISAQKPEIQSPMPPMTPGNSENVENRKRGGFS 134

  Fly   467 KPDDGTEEYLCKWQSLPYAESTWEDAALVLRKWQRCAEQFNDRESSKCTPSRHCRVIKYRPKFSR 531
            .|..|.|        ||...|. ..|..|        ......|||....|....:.:..|.|
 Worm   135 SPFLGIE--------LPKPLSK-RSATFV--------PPLIGSESSSSGGSSSSTIQEKIPPF-- 180

  Fly   532 IKNQPEFL----SSGLT--------LRDYQMDGLNWL---LHSWCKEN----SVILADEMGLGKT 577
            |.|:.:.|    :|.:|        ||.:|..|:.::   |.....:|    ..||||:|||||:
 Worm   181 ILNEQDILDRKTTSAVTVDTRFARHLRPHQKSGIQFIFDRLRRGSGKNGGGGGAILADDMGLGKS 245

  Fly   578 IQTICFLYSLFK----IHHLYGPFLCVVPLSTMTAWQREFDLWAPDM-----------NVVTYLG 627
            :||:...::|.|    ...|....|.:||.|.:..|:.|||.|...|           ::.||..
 Worm   246 LQTMAATWALLKGSKTAQQLANSCLIIVPSSLVNNWKAEFDKWWRLMRFPAVIALTANDITTYQS 310

  Fly   628 DIKSRELIQQYEWQFESSKRLKFNCILTTYEIVLKDKQFLGTLQWAALLVDEAHRLKNDDSLLYK 692
            .||    :..|              ::.:|::..:..:.|..:::..::.||.|:|||.|..|.|
 Worm   311 TIK----LMPY--------------LVISYDLAQRHVEKLKIIRFDVMVCDEGHKLKNLDGKLRK 357

  Fly   693 SLKEFDTNHRLLITGTPLQNSLKELWALLHFIMPDKFDTWENFEVQHGNAEDKGYTRLHQQLEPY 757
            :|...:...||::||||:||..:|.::||.|:.|..|.:...|.....:..:    :|::.::..
 Worm   358 TLLSLEIPRRLILTGTPMQNDFEEFYSLLDFVRPSVFGSIVEFRKMCSDRPE----QLNELIDEC 418

  Fly   758 ILRRVKKDVE-KSLPAKVEQILRVEMTSLQKQYYKWILTKNFDALRKGKRGSTSTFLNIVIELKK 821
            :|||...||: |.||.|.|.||....:.:||..:..|.    |.:       |...|:::...::
 Worm   419 MLRRTAADVDLKHLPEKHEYILFCAASPIQKHVHSEIC----DYM-------TGDALSLIFFARQ 472

  Fly   822 CCNHAALIRPSEFELMGLQQDEALQTLL-------------KGSGKL-VLLDKLLC-RLKETGHR 871
            ..||..|:..:..|.....:......||             |.|||| .|:|.:.| ||.:  ..
 Worm   473 LANHPKLLLDNLREKTEKSKAHKHSPLLLAFDGAHMPRGGVKESGKLTALVDMIKCFRLLQ--EC 535

  Fly   872 VLIFSQMVRMLDVLADYLQKRHFPFQRLDGSIKGEMRRQALDHFNAEGSQDFCFLLSTRAGGLGI 936
            .:|.|..:..||::....:..:|...||||..:...|::.:..||........|||||:|||:|:
 Worm   536 TVIVSNYIETLDMIQQLCEYLNFKVLRLDGKTQVPDRQKLVRTFNDHRDPSNIFLLSTKAGGVGL 600

  Fly   937 NLATADTVIIFDSDWNPQNDLQAQARAHRIGQKNQVNIYRLVTARSVEEQIVERAKQKMVLDHLV 1001
            ||..|..:::|||||||.||.||.||..|.||....:||||:|..::||::::|..:|..|..::
 Worm   601 NLIGASRLVLFDSDWNPANDQQAMARIWRDGQVRPCHIYRLITTGTIEEKMLQRQIKKTGLGCVI 665

  Fly  1002 --IQRMDTTG-------RTVLDKSGNGHSSNSNPF----------------NKDDLSAILKFGAE 1041
              |:..||..       :.:...:|:....|::..                .:||...:::..||
 Worm   666 DAIEVGDTIATFTDEDLKDIFTFTGSATECNTHDLCECPCDGCGMLENEMDEEDDGDDVVENDAE 730

  Fly  1042 ELFK-----------DEQEHDDDLVCDI-DEILRRAETRNEDPE--MPADDLLSAFKVASIA 1089
            ::.|           ||:..|::|..|: ||::   |...|.||  .||........:||:|
 Worm   731 KIDKSGKIDKIDSDDDEEADDEELEADVTDEVV---EDSQEPPEATKPAVAAAGLRTIASLA 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chd1	NP_001245851.1	CD1_tandem_CHD1-2_like	339..421	CDD:349313	19/78 (24%)
		CD2_tandem	454..508	CDD:349306	12/53 (23%)
		PLN03142	531..>1066	CDD:215601	169/621 (27%)
		CDH1_2_SANT_HL1	1205..1298	CDD:465731
		DUF4208	1521..1610	CDD:464035
rad-54.B	NP_001255913.1	HepA	<206..661	CDD:440319	146/489 (30%)